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Department of Medicine

Gastroenterology

Carcinoma

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Hepatocellular Carcinoma In Pakistan: Where Do We Stand?, Amna Subhan Butt, Z Abbas, Wasim Jafri Oct 2012

Hepatocellular Carcinoma In Pakistan: Where Do We Stand?, Amna Subhan Butt, Z Abbas, Wasim Jafri

Department of Medicine

Evidence Acquisition: The age-standardized rate for HCC is 7.64/100 000 in males and 2.8/100 000 in females. Male to female ratio is 3.6:1. Usual age of presentation is in the fifth and sixth decade. Most patients present with advanced disease, as they are not in a regular surveillance program. This is more so for patients with NBNC chronic liver disease. As many sonologists in Pakistan are practicing without sufficient training to pick up early lesions, alpha-fetoprotein is still recommended to compliment ultrasound in the surveillance of HCC.

Results: Majority of HCC patients present with nonresectable disease. Interventions such as transarterial …