Medicine and Health Sciences Commons^™

Non-Nutritive Suck Burst Pattern Stability In Extremely Premature Infants, Alejandra Marquez

College of Education and Human Sciences: Dissertations, Theses, and Student Research

The development of non-nutritive suck (NNS) burst dynamics in preterm infants reflects the integrity of the brain and is used clinically to assess feeding readiness and orofacial motor development (Mizuno and Ueda, 2005). The application of NNS analytics in the present report represents one outcome measurement set that is part of an ongoing clinical trial involving extremely preterm infants (EPI’s,[GA]) randomized to receive either pulsed orocutaneous stimulation therapeutics or a sham (blind pacifier), in conjunction with salivary sampling twice weekly to map gene expression of key proteins involved in neural development and molecular sensing of feeding related pathways in the …

Automatic Feature Discrimination Of Non-Nutritive Suck Dynamics Among Extremely Preterm Infants., Mckenzie Ann Ochoa

College of Education and Human Sciences: Dissertations, Theses, and Student Research

Prematurity is the leading cause of death in the first month of life. Neonates are forced to engage the extrauterine environment with an underdeveloped nervous systems, with limited connectivity between orofacial sensorimotor anatomy, brainstem pattern-generating circuits, and sensory-driven thalamocortical inputs to layer IV of the neocortex. This is correlated with an inability to produce the complex neuromotor behaviors of oral feeding. The NTrainer System is an assessment and treatment tool that promotes ororhythmic motor patterning in preterm infants though pulsed orocutaneous stimulation to improve NNS.

This report represents an interim analysis of NNS development among 42 extremely preterm infants enrolled …