Medicine and Health Sciences Commons^™

A Dna Computer For Glioblastoma Multiforme Diagnosis And Drug Delivery, Sumaiya F. Hashmi

CMC Senior Theses

Glioblastoma multiforme (GBM) is a debilitating malignant brain tumor with expected patient survival of less than a year and limited responsiveness to most treatments, often requiring biopsy for diagnosis and invasive surgery for treatment. We propose a DNA computer system, consisting of input, computation, and output components, for diagnosis and treatment. The input component will detect the presence of three GBM biomarkers: vascular endothelial growth factor (VEGF), caveolin-1α (CAV), and B2 receptors. The computation component will include indicator segments for each of these genes, and ensure that output is only released if all the biomarkers are present. The output component …

A Machine Learning Approach To Diagnosis Of Parkinson’S Disease, Sumaiya F. Hashmi

CMC Senior Theses

I will investigate applications of machine learning algorithms to medical data, adaptations of differences in data collection, and the use of ensemble techniques.

Focusing on the binary classification problem of Parkinson’s Disease (PD) diagnosis, I will apply machine learning algorithms to a primary dataset consisting of voice recordings from healthy and PD subjects. Specifically, I will use Artificial Neural Networks, Support Vector Machines, and an Ensemble Learning algorithm to reproduce results from [MS12] and [GM09].

Next, I will adapt a secondary regression dataset of PD recordings and combine it with the primary binary classification dataset, testing various techniques to consolidate …

The Silhouettes Of Autism, Chloe J. Dobbert

CMC Senior Theses

My passion as a student at the Claremont Colleges is to help children with Autism Spectrum Disorder grow and learn as normal children and to help prepare them for life outside the Autism Center at Claremont McKenna College. In my thesis project, I am exploring the concept of silhouettes through photography and my perceptions of the stories told to me by the children I teach. Esthetically, I am inspired by Kara Walker’s installation of large cutout silhouettes but I am using different mediums to accomplish my project: Artistically, I am inspired by the detailed descriptions of the obsessive stories and …

Heart Attack Experiences Described In Weblogs: An Analysis Of Sex Differences, Stephanie R. Morley

CMC Senior Theses

Heart disease is the leading cause of death for both men and women (Kochanek, Xu, Murphy, Miniño & Kung, 2011). Every year in the United States, more than 600,000 people die from heart disease, which amounts to roughly a quarter of all deaths (Kochanek et al., 2011). Heart attacks account for a large portion of the deaths attributed to heart disease, and include sudden cardiac arrest or chronic cases of heart trouble that develop into heart attack after an extended period of time. Heart attacks affect approximately 935,000 Americans each year, with roughly two-thirds of people experiencing them for a …