Medicine and Health Sciences Commons^™

Effects Of Temperature On Emergence And Seasonality Of West Nile Virus In California, David M. Hartley, Christopher M. Barker, Arnaud Le Menach, Tianchan Niu, Holly Gaff, William K. Reisen

Biological Sciences Faculty Publications

Temperature has played a critical role in the spatiotemporal dynamics of West Nile virus transmission throughout California from its introduction in 2003 through establishment by 2009. We compared two novel mechanistic measures of transmission risk, the temperature-dependent ratio of virus extrinsic incubation period to the mosquito gonotrophic period (BT), and the fundamental reproductive ratio (R₀) based on a mathematical model, to analyze spatiotemporal patterns of receptivity to viral amplification. Maps of BT and R₀ were created at 20-km scale and compared throughout California to seroconversions in sentinel chicken flocks at half-month intervals. Overall, estimates of BT and …