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Full-Text Articles in Medicine and Health Sciences
Maternal And Neonatal Vitamin D Binding Protein Polymorphisms And 25-Hydroxyvitamin D Cutoffs As Determinants Of Neonatal Birth Anthropometry, Spyridon N. Karras, Erdinç Dursun, Merve Alaylıoğlu, Duygu Gezen-Ak, Stefan Pilz, Cedric Annweiler, Fatme Al Anouti
Maternal And Neonatal Vitamin D Binding Protein Polymorphisms And 25-Hydroxyvitamin D Cutoffs As Determinants Of Neonatal Birth Anthropometry, Spyridon N. Karras, Erdinç Dursun, Merve Alaylıoğlu, Duygu Gezen-Ak, Stefan Pilz, Cedric Annweiler, Fatme Al Anouti
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BACKGROUND: Vitamin D-binding protein (VDBP) is a vital regulator of optimal vitamin D homeostasis and bioavailability. Apart from its well-documented role as a key component in vitamin D dynamic transfer and circulation, it has a myriad of immunoregulatory functions related to innate immunity, which becomes particularly critical in states of increased immunological tolerance including pregnancy. In this regard, VDBP dyshomeostasis is considered to contribute to the development of several fetal, maternal, and neonatal adverse outcomes. However, precise physiological pathways, including the contribution of specific VDBP polymorphisms behind such phenomena, are yet to be fully deciphered. Our aim was to assess …
Pre-Pregnancy Excess Weight Association With Maternal Sociodemographic, Anthropometric And Lifestyle Factors And Maternal Perinatal Outcomes, Dimitrios Papandreou, Maria Mantzorou, Stefanos Tyrovolas, Eleni Pavlidou, Georgios Antasouras, Evmorfia Psara, Efthymios Poulios, Georgios K. Vasios, Constantinos Giaginis
Pre-Pregnancy Excess Weight Association With Maternal Sociodemographic, Anthropometric And Lifestyle Factors And Maternal Perinatal Outcomes, Dimitrios Papandreou, Maria Mantzorou, Stefanos Tyrovolas, Eleni Pavlidou, Georgios Antasouras, Evmorfia Psara, Efthymios Poulios, Georgios K. Vasios, Constantinos Giaginis
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BACKGROUND: Pre-pregnancy excess weight is an important factor for adverse maternal perinatal outcomes; however, data for Greek women remain limited. Therefore, the aim of the present work was to evaluate the relation between pre-pregnant weight status and sociodemographic, anthropometric and lifestyle factors and maternal perinatal outcomes. METHODS: In the present cross-sectional study, 5133 healthy women were enrolled from nine different Greek regions after applying specific inclusion and exclusion criteria. Validated questionnaires were used to assess the sociodemographic characteristics and certain lifestyle factors of the study population. Anthropometric and clinical data were retrieved from medical history files of the women, including …
Upregulation Of Irisin And Vitamin D-Binding Protein Concentrations By Increasing Maternal 25-Hydrovitamin D Concentrations In Combination With Specific Genotypes Of Vitamin D-Binding Protein Polymorphisms, Spyridon N. Karras, Erdinç Dursun, Merve Alaylıoglu, Duygu Gezen-Ak, Fatme Al Anouti, Stefan Pilz, Pawel Pludowski, Edward Jude, Kalliopi Kotsa
Upregulation Of Irisin And Vitamin D-Binding Protein Concentrations By Increasing Maternal 25-Hydrovitamin D Concentrations In Combination With Specific Genotypes Of Vitamin D-Binding Protein Polymorphisms, Spyridon N. Karras, Erdinç Dursun, Merve Alaylıoglu, Duygu Gezen-Ak, Fatme Al Anouti, Stefan Pilz, Pawel Pludowski, Edward Jude, Kalliopi Kotsa
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Dyshomeostasis of vitamin D-binding protein (VDBP) has been implicated in the patho-genesis of various pregnancy complications, including preeclampsia, preterm birth, gestational di-abetes, and adverse metabolic profiles in the offspring. VDBP polymorphisms have been consistently reported to contribute to this intriguing interplay. Until recently, the effects of VDBP poly-morphism heterogeneity on maternal and neonatal adipomyokine profiles have not been investi-gated, specifically after incorporating the different maternal and neonatal 25-hydroxyvitamin D concentration cut-offs at birth. We aimed to investigate the potential effects of maternal and neonatal VDBP polymorphisms on adiponectin, irisin, and VDBP concentrations at birth, according to different cut-offs of vitamin …
Machine Learning Techniques For Predicting Depression And Anxiety In Pregnant And Postpartum Women During The Covid-19 Pandemic: A Cross-Sectional Regional Study, Radwan Qasrawi, Malak Amro, Stephanny Vicunapolo, Diala Abu Al-Halawa, Hazem Agha, Rania Abu Seir, Maha Hoteit, Reem Hoteit, Sabika Allehdan, Nouf Behzad, Khlood Bookari, Majid Alkhalaf, Haleama Al-Sabbah, Eman Badran, Reema Tayyem
Machine Learning Techniques For Predicting Depression And Anxiety In Pregnant And Postpartum Women During The Covid-19 Pandemic: A Cross-Sectional Regional Study, Radwan Qasrawi, Malak Amro, Stephanny Vicunapolo, Diala Abu Al-Halawa, Hazem Agha, Rania Abu Seir, Maha Hoteit, Reem Hoteit, Sabika Allehdan, Nouf Behzad, Khlood Bookari, Majid Alkhalaf, Haleama Al-Sabbah, Eman Badran, Reema Tayyem
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Background: Maternal depression and anxiety are significant public health concerns that play an important role in the health and well-being of mothers and children. The COVID-19 pandemic, the consequential lockdowns and related safety restrictions worldwide negatively affected the mental health of pregnant and postpartum women. Methods: This regional study aimed to develop a machine learning (ML) model for the prediction of maternal depression and anxiety. The study used a dataset collected from five Arab countries during the COVID-19 pandemic between July to December 2020. The population sample included 3569 women (1939 pregnant and 1630 postpartum) from five countries (Jordan, Palestine, …