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Journal Club: Glymphatic System In Neurodegenerative Diseases, Ronald G. Lott Iii, Xavier Zonna, Samuel Wlasowicz

Advances in Clinical Medical Research and Healthcare Delivery

Neurodegenerative diseases such as Alzheimer's Disease impact a multitude of individuals worldwide. The neural Glymphatic system is a relatively newly discovered cellular transport pathway within the brain that has been implicated in neurodegenerative diseases. This article serves to provide a journal club review of current literature on the Glymphatic system to raise awareness of this system and its potential for future treatment and prevention of neurodegenerative conditions.

The Management Of Newly Diagnosed Probable Creutzfeldt-Jakob Disease In Acute Rehabilitation Setting: A Case Report, Royce Copeland, Shefali Amin, Anthony Donato

Advances in Clinical Medical Research and Healthcare Delivery

Abstract

Creutzfeldt-Jakob disease is a rare and fatal neurodegenerative disease. The purpose of this report is to demonstrate the role of inpatient rehabilitation for a patient recently diagnosed with probable Creutzfeldt-Jakob disease. A 62-year-old male was readmitted to an acute care hospital after a recent mechanical fall. For several weeks, he had a constellation of symptoms, including cognitive impairment and progressive memory loss, gait and postural instability, 20 pounds of unintentional weight loss, visual hallucinations, myoclonus, and hypophonia. After an extensive workup, a diagnosis of probable Creutzfeldt-Jakob disease was made, and he was transferred to an acute inpatient rehabilitation hospital. …