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Medicine and Health Sciences Commons

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Zucker School of Medicine at Hofstra/Northwell

Research & Experimental

Medical Sciences

Publication Year

Articles 1 - 8 of 8

Full-Text Articles in Medicine and Health Sciences

Metabolic And Microstructural Alterations In The Sle Brain Correlate With Cognitive Impairment, M. Mackay, A. Vo, C. C. Tang, W. Anderson, N. J. Ploran, C. Aranow, P. Watson, B. T. Volpe, B. Diamond, D. Eidelberg, +5 Additional Authors Jan 2019

Metabolic And Microstructural Alterations In The Sle Brain Correlate With Cognitive Impairment, M. Mackay, A. Vo, C. C. Tang, W. Anderson, N. J. Ploran, C. Aranow, P. Watson, B. T. Volpe, B. Diamond, D. Eidelberg, +5 Additional Authors

Journal Articles

No abstract provided.


Patterns Of Ana(+) B Cells For Sle Patient Stratification, J. Suurmond, Y. Atisha-Fregoso, A. N. Barlev, S. A. Calderon, C. Mackay, Z. Aranow, B. Diamond Jan 2019

Patterns Of Ana(+) B Cells For Sle Patient Stratification, J. Suurmond, Y. Atisha-Fregoso, A. N. Barlev, S. A. Calderon, C. Mackay, Z. Aranow, B. Diamond

Journal Articles

No abstract provided.


Erythropoiesis: Insights Into Pathophysiology And Treatments In 2017, A. Zivot, J. M. Lipton, A. Narla, L. Blanc Jan 2018

Erythropoiesis: Insights Into Pathophysiology And Treatments In 2017, A. Zivot, J. M. Lipton, A. Narla, L. Blanc

Journal Articles

No abstract provided.


Analysis Of Menstrual Effluent: Diagnostic Potential For Endometriosis, L. A. Warren, A. Shih, S. M. Renteira, T. Seckin, B. Blau, K. Simpfendorfer, C. N. Metz, P. K. Gregersen Jan 2018

Analysis Of Menstrual Effluent: Diagnostic Potential For Endometriosis, L. A. Warren, A. Shih, S. M. Renteira, T. Seckin, B. Blau, K. Simpfendorfer, C. N. Metz, P. K. Gregersen

Journal Articles

No abstract provided.


Nicotinic Acetylcholine Receptor-Mediated Protection Of The Rat Heart Exposed To Ischemia Reperfusion, S. A. Mavropoulos, N. S. Khan, A. C. J. Levy, B. T. Faliks, C. P. Sison, V. A. Pavlov, Y. Zhang, K. Ojamaa Jan 2017

Nicotinic Acetylcholine Receptor-Mediated Protection Of The Rat Heart Exposed To Ischemia Reperfusion, S. A. Mavropoulos, N. S. Khan, A. C. J. Levy, B. T. Faliks, C. P. Sison, V. A. Pavlov, Y. Zhang, K. Ojamaa

Journal Articles

No abstract provided.


Early Efficacy Trial Of Anakinra In Corticosteroid-Resistant Autoimmune Inner Ear Disease, A. Vambutas, M. Lesser, V. Mullooly, S. Pathak, G. Zahtz, L. M. Rosen, E. Goldofsky Jan 2014

Early Efficacy Trial Of Anakinra In Corticosteroid-Resistant Autoimmune Inner Ear Disease, A. Vambutas, M. Lesser, V. Mullooly, S. Pathak, G. Zahtz, L. M. Rosen, E. Goldofsky

Journal Articles

BACKGROUND. Autoimmune inner ear disease (AIED) is a rare disease that results in progressive sensorineural hearing loss. Patients with AIED initially respond to corticosteroids; however, many patients become unresponsive to this treatment over time, and there is no effective alternative therapy for these individuals. METHODS. We performed a phase I/II open-label, single-arm clinical trial of the IL-1 receptor antagonist anakinra in corticosteroid-resistant AIED patients. Given that the etiology of corticosteroid resistance is likely heterogeneous, we used a Simon 2-stage design to distinguish between an unacceptable (= 30%) response rate to anakinra therapy. Subjects received 100 mg anakinra by subcutaneous injection …


Early Specific Cognitive-Behavioural Psychotherapy In Subjects At High Risk For Bipolar Disorders: Study Protocol For A Randomised Controlled Trial, A. Pfennig, K. Leopold, A. Bechdolf, C. U. Correll, M. Holtmann, M. Lambert, C. Marx, T. D. Meyer, G. Juckel, M. Bauer, +5 Additional Authors Jan 2014

Early Specific Cognitive-Behavioural Psychotherapy In Subjects At High Risk For Bipolar Disorders: Study Protocol For A Randomised Controlled Trial, A. Pfennig, K. Leopold, A. Bechdolf, C. U. Correll, M. Holtmann, M. Lambert, C. Marx, T. D. Meyer, G. Juckel, M. Bauer, +5 Additional Authors

Journal Articles

Background: Bipolar disorders (BD) are among the most severe mental disorders with first clinical signs and symptoms frequently appearing in adolescence and early adulthood. The long latency in clinical diagnosis (and subsequent adequate treatment) adversely affects the course of disease, effectiveness of interventions and health-related quality of life, and increases the economic burden of BD. Despite uncertainties about risk constellations and symptomatology in the early stages of potentially developing BD, many adolescents and young adults seek help, and most of them suffer substantially from symptoms already leading to impairments in psychosocial functioning in school, training, at work and in their …


Radiation Absorbed Dose To The Basal Ganglia From Dopamine Transporter Radioligand F-18-Fpcit, W. Robeson, V. Dhawan, Y. L. Ma, D. Bjelke, C. Margouleff, T. Chaly, D. Eidelberg Jan 2014

Radiation Absorbed Dose To The Basal Ganglia From Dopamine Transporter Radioligand F-18-Fpcit, W. Robeson, V. Dhawan, Y. L. Ma, D. Bjelke, C. Margouleff, T. Chaly, D. Eidelberg

Journal Articles

Our previous dosimetry studies have demonstrated that for dopaminergic radiotracers, F-18-FDOPA and F-18-FPCIT, the urinary bladder is the critical organ. As these tracers accumulate in the basal ganglia (BG) with high affinity and long residence times, radiation dose to the BG may become significant, especially in normal control subjects. We have performed dynamic PET measurements using F-18-FPCIT in 16 normal adult subjects to determine if in fact the BG, although not a whole organ, but a well-defined substructure, receives the highest dose. Regions of interest were drawn over left and right BG structures. Resultant time-activity curves were generated and used …