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Detection Of The Dietary Xenoglycan N-Glycolylneuraminic Acid (Neu5gc) And Anti-Neu5gc Antibodies Within Reproductive Tracts Of Male And Female Infertility Subjects, Julie M. Sroga, Diana H. Wu, Fang Ma, Eilllen Tecle, Ilana B. Ressler, Rose Maxwell, Rachael Ferrari, Leah Whigham, Pascal Gagneux, Steven Lindheim
Detection Of The Dietary Xenoglycan N-Glycolylneuraminic Acid (Neu5gc) And Anti-Neu5gc Antibodies Within Reproductive Tracts Of Male And Female Infertility Subjects, Julie M. Sroga, Diana H. Wu, Fang Ma, Eilllen Tecle, Ilana B. Ressler, Rose Maxwell, Rachael Ferrari, Leah Whigham, Pascal Gagneux, Steven Lindheim
Obstetrics and Gynecology Faculty Publications
Objective
To assess the frequency of dietary xenoglycanNeu5Gc and antibodies in males and females and its impact on fertility.
Design
Prospective study of semen, uterine lavage, and follicular fluid from subjects undergoing infertility evaluation or in vitro fertilization (IVF) and fertile controls.
Setting
University based infertility program.
Participants
Males (n=23) and females (n=27) undergoing semen analysis and saline infusion sonography as part of their diagnostic evaluation and 37 women undergoing IVF were compared to fertile male (n=15) and female (n=14) controls.
Intervention
Neu5Gc was measured by affinity purified antibody staining on Western blots, flow cytometry, and by high performance liquid …