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Wright State University

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Anatomy

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The Effect Of Soleus Fatigue During Sidestep Cutting Maneuvers: Implications For The Acl, Michael William Ciesa Jan 2018

The Effect Of Soleus Fatigue During Sidestep Cutting Maneuvers: Implications For The Acl, Michael William Ciesa

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The soleus muscle is a monoarticular plantarflexor composed slow-twitch fatigue-resistant muscle fibers. Through its attachment to the proximal tibia, contraction of the soleus muscle in a closed kinetic chain (when the foot is planted) produces a posterior pulling force on the posterior proximal tibia. The anterior cruciate ligament (ACL) is responsible for preventing anterior displacement of the tibia relative to the femur. Through the production of a posterior pulling force on the tibia, soleus muscle contraction in a closed kinetic chain could help reduce strain on the ACL. Fatigue is a neuromuscular phenomenon that can alter biomechanical strategies during athletics …


Is Polyvinylidene Diflouride (Pvdf) Film Biocompatible In The Murine Cochlea?, Robert Maxwell Jaggers Jan 2015

Is Polyvinylidene Diflouride (Pvdf) Film Biocompatible In The Murine Cochlea?, Robert Maxwell Jaggers

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Polyvinylidene fluoride (PVDF) film, a biomaterial that is an integral part of a Totally Implantable Sustainable Hearing Aide (TISHA) device, was examined to determine its biocompatibility within the murine cochlea. The biofilm was implanted in the ear using a round window cochleostomy in 7-9 week old male C57BL/6 mice. Three test groups containing seven mice each were implanted with PVDF film. Each mouse received a sham surgery on the non-implanted cochlea. Three test groups were examined at 48 hours, 3 weeks, and 3 months. At the end of this time the mouse was euthanized, the tissue containing the cochlea was …


Maturation Of The Carotid Body Oxygen-Sensor During Rat Development, Julia Paulet Jan 2012

Maturation Of The Carotid Body Oxygen-Sensor During Rat Development, Julia Paulet

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Carotid bodies (CB) are paired, oxygen-sensing organs located in the bifurcation of the carotid artery that act as peripheral chemoreceptors in the detection of hypoxic, hypercapnic and acidotic levels in the arterial blood. CBs respond to these fluctuations in blood gases by initiating firing of the carotid sinus nerve. This ultimately results in the appropriate ventilatory change to restore blood gases to their physiological levels. Studies have shown that the hypoxic response of the carotid body in juvenile mammals is low, but as maturation occurs this response is strengthened and clearly exhibited in adults. One theory suggests mitochondria play a …


Electrical Brain Stimulation And Depressive-Like Behavior In Guinea Pigs, Nadia Kardegar Jan 2012

Electrical Brain Stimulation And Depressive-Like Behavior In Guinea Pigs, Nadia Kardegar

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Maternal separation in guinea pigs produces a biphasic response consisting of an active behavior phase (vocalizations and locomotor activity) followed by a phase of passive depressive-like behavior (crouched stance, piloerection, and eye closure). The mechanism for the transition from the active to the passive phase is unknown. One suggestion is that continual activity of neural circuitry producing active behavior eventually leads to the expression of passive behaviors. The purpose of this study was to test this possibility. Guinea pigs were assigned to experimental and control groups. The experimental group received daily stimulation of the bed nucleus stria terminalis (BNST) to …