Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Anatomy and Physiology (2)
- ASL (1)
- Arterial Spin Labeling (1)
- Biochemistry (1)
- Cardiomyocyte (1)
-
- Cellular Biology (1)
- Cortisol (1)
- DCM (1)
- Developmental Psychology (1)
- Dilated cardiomyopathy (1)
- Glycosylation (1)
- Guinea pig (1)
- Heart failure (1)
- Hypothalamic-pituitary-adrenal (1)
- Infralimbic (1)
- Inter-session reliability (1)
- MRI (1)
- Molecular Biology (1)
- Neurobiology (1)
- PCASL (1)
- PSEUDO-CONTINUOUS (1)
- Perfusion (1)
- Prefrontal cortex (1)
- Prelimbic (1)
- Reliability (1)
- Social buffering (1)
- Social development (1)
Articles 1 - 3 of 3
Full-Text Articles in Medicine and Health Sciences
Assessment Of Pseudo-Continuous Arterial Spin Labeling (Pcasl) Inter-Session Reliability In The Quantification Of Cerebral Perfusion, Mohammad Ahmad Awad
Assessment Of Pseudo-Continuous Arterial Spin Labeling (Pcasl) Inter-Session Reliability In The Quantification Of Cerebral Perfusion, Mohammad Ahmad Awad
Browse all Theses and Dissertations
Arterial spin labeling (ASL) is a magnetic resonance imaging (MRI) technique used for measuring cerebral blood flow (CBF) in a completely non-ionizing and non invasive fashion. ASL is useful in perfusion studies on healthy adult & pediatric subjects, individuals who need multiple follow-ups, and patients with varying cerebrovascular diseases where changes in CBF can be used as an indicator of tissue viability. We used a variation of the ASL technique known as pseudo-continuous ASL (pCASL). This form of ASL is the clinical standard (Alsop et al., 2015). However, it is not well documented the that pCASL is reliable between sessions …
Social Buffering By Unfamiliar Adult Males In Periadolescent Guinea Pigs: The Effects On Hpa Axis Activity And Fos Induction In The Medial Prefrontal Cortex, Alexander Bertke
Social Buffering By Unfamiliar Adult Males In Periadolescent Guinea Pigs: The Effects On Hpa Axis Activity And Fos Induction In The Medial Prefrontal Cortex, Alexander Bertke
Browse all Theses and Dissertations
In the guinea pig, the ability of the mother’s presence to buffer hypothalamic-pituitary- adrenal (HPA) axis activation in her young during exposure to stressful stimuli has been well documented. Under similar testing conditions, other conspecifics (littermates, other adult females) are less effective in doing so. The effect does seem to wane with age but is still present to a significant degree in offspring approaching adolescence. However, we recently observed that an unfamiliar adult male buffered HPA axis activation and increased Fos expression in the prefrontal cortex of preweaning infants exposed to a novel enclosure at both 60 and 120 minutes …
Effect Of Hybrid/Complex N-Glycosylation On Cardiac Voltage-Gated Ion Channel Expression, Austin R. Parrish
Effect Of Hybrid/Complex N-Glycosylation On Cardiac Voltage-Gated Ion Channel Expression, Austin R. Parrish
Browse all Theses and Dissertations
Dilated cardiomyopathy (DCM) is one the most common forms of heart failure, with the majority of cases being idiopathic. Dr. Bennett’s laboratory previously showed that deletion of the Mgat1 gene in cardiomyocytes only (Mgat1KO) is sufficient to cause DCM leading to heart failure and early death. The Mgat1 gene product, GlcNAcT1, is responsible for initiating the formation of hybrid/complex N-glycosylation. These data suggest a link between abnormal glycosylation and heart disease; however, there is a mystery of how the specific changes in glycosylation contribute to heart disease etiology and progression. The proper function and gating of voltage-gated Na+ channels (Nav) …