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Full-Text Articles in Medicine and Health Sciences
The Influence Of Age At Menarche And Hamstrings Fatigue On Knee Biomechanics, Stephanie Eileen Field
The Influence Of Age At Menarche And Hamstrings Fatigue On Knee Biomechanics, Stephanie Eileen Field
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Anterior cruciate ligament (ACL) injury is 4-8 times more likely to occur in females than in males and is associated with significant morbidity. The mechanism underlying the gender disparity in non-contact ACL injuries is likely multifactorial, and may be influenced by a variety of risk factors. This study examines the influence of age at menarche and neuromuscular fatigue of the hamstrings muscles on knee biomechanics. Twelve female athletes performed drop vertical jump (DVJ) tasks before and after a fatiguing protocol utilizing a glute-ham bench. Knee kinematics and kinetics were recorded during the contact phase of the DVJ. The results of …
Translocation And Phosphorylation Of Ampa Receptors Following Transcranial Direct Current Stimulation In Vivo, Justin Andrew Stafford
Translocation And Phosphorylation Of Ampa Receptors Following Transcranial Direct Current Stimulation In Vivo, Justin Andrew Stafford
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Transcranial direct current stimulation (tDCS) is the current technique used clinically to attenuate the effects of various neurological related deficits and augment functions such as memory and learning. The cellular and molecular mechanisms behind tDCS remain largely unknown and this study provides some of the first insights into the mechanisms behind tDCS. Direct current stimulation has been used to increase levels of long term potentiation (LTP) ex vivo suggesting that this stimulation has an effect on the LTP mechanisms of action. Subcellular protein extraction and fractionation methods were used to isolate synaptoneurosomes from various brain regions to assess the effects …
The Timing Of Fluoxetine, Simvastatin And Ascorbic Acid Administration In A Post-Ischemic Stroke Environment Affects Infarct Volume And Hemorrhagic Transformation Frequency, Neal R. Verma
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Previous animal experiments have indicated that administration of fluoxetine and simvastatin at 20-26 hours post-stroke decreases the volume of ischemic infarcts. This experiment expanded on previous experiments by adding ascorbic acid to the post-stroke regimen, initiating simvastatin pre-stroke, and adding a third initiation time frame (48-54 hours). Male retired breeder Sprague-Dawley rats were on simvastatin for 7 days prior to stroke induction. Combined medications of 5 milligrams/kilogram of fluoxetine, 1 milligram/kilogram of simvastatin and 20 milligrams/kilogram of ascorbic acid were orally administered at 6-12 hours, 20-26 hours, or 48-54 hours, respectively, following stroke induction. Adult rats that were treated 20-26 …