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Epilepsy Risk Among Survivors Of Intensive Care Unit Hospitalization For Sepsis, Tresah C. Antaya, Britney N. Allen, Lucie Richard, Salimah Z. Shariff, Gustavo Saposnik, Jorge Burneo Jan 2020

Epilepsy Risk Among Survivors Of Intensive Care Unit Hospitalization For Sepsis, Tresah C. Antaya, Britney N. Allen, Lucie Richard, Salimah Z. Shariff, Gustavo Saposnik, Jorge Burneo

Neuroepidemiology Research Unit Project Summaries

Research Summary: Key Findings

  • 407 (0.28%) patients developed epilepsy within 2 years of their ICU discharge, 103 (25.3%) of whom were exposed to sepsis.
  • Sepsis survivors were significantly more likely to develop epilepsy, relative to non-septic ICU survivors.
  • Among sepsis survivors, epilepsy risk increased with age and was higher among those with chronic kidney disease.



Transition From Paediatric To Adult Healthcare: Readiness And Experiences Of Canadian Adolescents And Young Adults Diagnosed With Epilepsy In Childhood, Alison S.B. Dasiewicz Mar 2017

Transition From Paediatric To Adult Healthcare: Readiness And Experiences Of Canadian Adolescents And Young Adults Diagnosed With Epilepsy In Childhood, Alison S.B. Dasiewicz

Electronic Thesis and Dissertation Repository

Documenting the transition from paediatric to adult healthcare is important to guide the delivery of developmentally appropriate healthcare. The objectives of this research were to quantify the transition readiness of adolescents and young adults (AYAs) diagnosed with epilepsy in childhood, explore its association with individual and familial factors, and describe transfer/transition experiences for AYAs and parents. Families and physicians were followed for ten years as part of the Health-Related Quality of Life in Children with Epilepsy Study and provided report using questionnaires.

The distribution of transition readiness indicates much room for improvement. Age was the only factor significantly associated with …


Assessing The Structural Validity Of The Measure Of Processes Of Care (Mpoc-20) In Children With Epilepsy, Kariym Christopher Joachim Dec 2014

Assessing The Structural Validity Of The Measure Of Processes Of Care (Mpoc-20) In Children With Epilepsy, Kariym Christopher Joachim

Electronic Thesis and Dissertation Repository

The goal of this thesis was to determine whether the 20-item Measure of Processes of Care (MPOC-20) questionnaire remains structurally/factorially valid among children with epilepsy, and to propose adaptations if it did not. Establishing the MPOC-20’s structural validity in this population makes it possible to draw conclusions on the potential effects of parent-perceived Family-Centred Care (FCC) on health outcomes within this population. Data came from the Health-related Quality of Life for Children with Epilepsy Study (HERQULES). Confirmatory Factor Analysis (CFA) indicated that the original five factor model fit poorly in children with epilepsy. An exploratory analysis within a CFA framework …


Depressive Symptoms In Mothers Of Children With New-Onset Epilepsy: A Prospective Study, Mark Anthony Ferro Apr 2011

Depressive Symptoms In Mothers Of Children With New-Onset Epilepsy: A Prospective Study, Mark Anthony Ferro

Electronic Thesis and Dissertation Repository

Having a child diagnosed with a chronic illness such as epilepsy is a major source of stress for caregivers. Up to half of mothers of children with epilepsy are at increased risk for clinical depression and symptoms of maternal depression are associated with poorer health outcomes in these children. The purpose of this study was to: 1) estimate the prevalence and course of depressive symptoms over 24 months among mothers of children with new-onset epilepsy; 2) identify subgroups of mothers that share similar trajectories of depressive symptoms; and, 3) assess the family factors involved in the causal pathway between maternal …