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Viable Influenza A Virus In Airborne Particles Expelled During Coughs Versus Exhalations, William G. Lindsley, Francoise M. Blachere, Donald H. Beezhold, Robert E. Thewlis, Bahar Noorbakhsh, Sreekumar Othumpangat, William T. Goldsmith, Cynthia M. Mcmillen, Michael E. Andrew, Carmen N. Burrell, John D. Noti
Viable Influenza A Virus In Airborne Particles Expelled During Coughs Versus Exhalations, William G. Lindsley, Francoise M. Blachere, Donald H. Beezhold, Robert E. Thewlis, Bahar Noorbakhsh, Sreekumar Othumpangat, William T. Goldsmith, Cynthia M. Mcmillen, Michael E. Andrew, Carmen N. Burrell, John D. Noti
Faculty & Staff Scholarship
Background To prepare for a possible influenza pandemic, a better understanding of the potential for the airborne transmission of influenza from person to person is needed.
Objectives The objective of this study was to directly compare the generation of aerosol particles containing viable influenza virus during coughs and exhalations.
Methods Sixty-one adult volunteer outpatients with influenza-like symptoms were asked to cough and exhale three times into a spirometer. Aerosol particles produced during coughing and exhalation were collected into liquid media using aerosol samplers.The samples were tested for the presence of viable influenza virus using a viral replication assay (VRA).
Results …