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Identifying Predictors For Inflammation-Induced Preterm Birth: A Murine Study, Tzu Ning Liu Bs, Jose Galaz Md, Nardhy Gomez-Lopez Phd Jun 2022

Identifying Predictors For Inflammation-Induced Preterm Birth: A Murine Study, Tzu Ning Liu Bs, Jose Galaz Md, Nardhy Gomez-Lopez Phd

Medical Student Research Symposium

Introduction: Preterm birth is the leading cause of neonatal morbidity and mortality worldwide. A large proportion of preterm deliveries is affected by intra-amniotic inflammation, which can occur in the presence (intra-amniotic infection) or absence (sterile intra-amniotic inflammation) of microbes. Studies have shown an association between intra-amniotic inflammation, cervical shortening, and changes in the cervicovaginal microbiome. However, their causal relationships are unknown. This study aims to determine the causality of intra-amniotic inflammation, cervical shortening, and cervicovaginal microbiome alterations.

Methods: Pregnant C57BL/6 dams received an ultrasound-guided intra-amniotic injection of an endotoxin lipopolysaccharide (LPS) or the alarmin interleukin-1 alpha (IL-1 alpha) on 16.5 …


Ultrasound Education Curriculum Increases First Year Student Visualization Ability Three-Fold, Joseph Files, Majd Faraj, Jared Hudson, Anna Kang, David Melville, Charles S. Day Jun 2022

Ultrasound Education Curriculum Increases First Year Student Visualization Ability Three-Fold, Joseph Files, Majd Faraj, Jared Hudson, Anna Kang, David Melville, Charles S. Day

Medical Student Research Symposium

Introduction: Ultrasound usage in identifying a subsheath within the first dorsal extensor compartment may be useful in determining cortisone shot effectiveness in alleviating pain for DeQuervain’s Tenosynovitis(1,2). However, no ultrasound educational curriculum has been established for non-radiologists(3-5). We hypothesize that an ultrasound training protocol will show marked improvement of anatomical knowledge and technical knowledge of how to utilize an ultrasound probe to visualize the first extensor compartment and any possible septation.

Materials & Methods: First-year medical students were polled for participation from a single medical school at a tertiary care academic medical center in the Midwest. Evaluations were developed and …