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Full-Text Articles in Medicine and Health Sciences
Patterns Of Fecal Progestagens, Estrogens, And Androgens Associated With Reproduction In Blue-Throated Piping Guans (Pipile Cumanensis), Leslie Ann Sterling, Helen Clawitter, Corinne P. Kozlowski, Michael Macek, Anne Tieber
Patterns Of Fecal Progestagens, Estrogens, And Androgens Associated With Reproduction In Blue-Throated Piping Guans (Pipile Cumanensis), Leslie Ann Sterling, Helen Clawitter, Corinne P. Kozlowski, Michael Macek, Anne Tieber
Undergraduate Research Symposium Posters
While fecal hormone analyses are routinely employed to monitor reproduction in mammals, few studies have used these techniques for monitoring reproductive events in birds. This study describes the endocrine patterns associated with reproduction in the blue-throated piping guan (Pipile cumanensis), a less threatened relative of the critically endangered Trinidad piping guan (P. pipile). Fecal samples were collected approximately once a week for 3 years from seven female guans and six male guans at the Saint Louis Zoo. Concentrations of fecal progestagens, estrogens, and androgens were quantified using commercially available enzyme immunoassays. Baseline progestagen concentrations for females …
The Role Of Notch Signaling On Heart Rate And Atrial Conduction, Somya Bhatnagar
The Role Of Notch Signaling On Heart Rate And Atrial Conduction, Somya Bhatnagar
Undergraduate Research Symposium Posters
Heart disease is the leading cause of death worldwide and can result in arrhythmias, or dysregulation in the electrical activation of the heart. Sick Sinus Syndrome (SSS) is characterized by sinus bradycardia (slowed heart rate, HR), slowed conduction through atrial myocardium, and can predispose to the development of atrial fibrillation. A developmental signaling pathway, Notch, regulates cellular identity through differentiation of cardiomyocytes (CMs) into cardiac conduction system-like cells. Previous data show that Notch electrically remodels the right atrium, causing slowed conduction velocity (CV) and hallmarks of SSS including sinus pauses, sinus bradycardia and a predisposition to atrial fibrillation. However, the …
Mu Opioid Receptor Desensitization In Inflammatory Pain, Matthew Bredder
Mu Opioid Receptor Desensitization In Inflammatory Pain, Matthew Bredder
Undergraduate Research Symposium Posters
Due to the epidemic level of opioid overdose deaths in the United States, improving the treatment of chronic pain has become a pressing concern. Opioid treatments such as fentanyl and morphine activate mu opioid receptors (MORs), causing an increase in dopamine release. Long term use of opioids, even as prescribed by a physician, can desensitize the MORs and lead to the appearance of withdrawal symptoms when the receptors are no longer stimulated. Since pain increases endogenous opioid release, we hypothesized that this increase may cause MOR desensitization and the appearance of withdrawal syndrome upon blockade of MORs, as seen in …