Medicine and Health Sciences Commons^™

Reduction Of Oxidative Stress And Storage Lesions (Rcsl) In Red Blood Cells - Analysis Of Ascorbic Acid (Aa), N-Acetylcysteine Amide (Ad4), And Serotonin (5-Ht), Shanmuka Gadiraju

Undergraduate Research Posters

Oxidative stress is a common occurrence in red blood cell (RBC) storage in blood banks throughout the world. Typically RBC units stored under routine standard protocol (stored in SAGM-CPD additive solution) can only be kept up to 42 days for transfusion usage before being discarded. I am studying the effects of Ascorbic Acid (AA), N-acetylcysteine amide (AD4), and Serotonin (5-HT) as additives in blood bank storage because I want to find out if these additives can reduce storage-induced oxidative stress on red blood cells (RBCs), in order to help my reader understand how potential blood storage additives can affect the …

Subjective Measures Of Mz And Dz Twins During Anxiety-Provoking Tasks, Sravya Uppalapati

Undergraduate Research Posters

Temporary anxiety is a healthy response to stress; however, continuous anxiety can threaten an individual’s day-to-day living by eliciting negative responses. In the study, monozygotic 84 (MZ) and 153 dizygotic (DZ) adolescent twins pairs, ages 15 to 20 years, participated in anxiety-provoking tasks and subjective experiences of anxiety were measured using subjective units of distress (SUDS). The twin participants were recruited through the Mid-Atlantic Twin Registry (MATR) at Virginia Commonwealth University. The twins participated in a carbon dioxide (CO₂) breathing task and a trier social stress task (TSST). The study aims were to evaluate the relationship between anxiety-provoking …

Umls::Association - Measuring The Association Between Biomedical Terms, Keith B. Herbert

Undergraduate Research Posters

UMLS::Association - A Semantic Association Framework for Biomedical Texts

Keith Herbert

Natural Language Processing Lab, Department of Computer Science

Introduction

We present UMLS::Association, a software package to explore the semantic association of biomedical terms with applications for literature-based discovery. Literature-based discovery is an endeavour to ”connect the dots” for scientists between the topics of their research and those of unexpected relevance. However, many approaches rely on the exact wording for the ideas in the research papers being analyzed. The Unified Medical Language System (UMLS) provides a way to map natural language phrases in these papers to sequences of abstract yet …

Incorporation Of Interprofessional Education And Special Care Dentistry Into Standard Dental School Curriculum, Marshall D. Adzima

Undergraduate Research Posters

According to dentistry, special needs is defined as individuals whose medical, physical, psychological, or social situations may make it necessary to modify normal dental routines in order to provide dental treatment for that individual. The population of special needs patients is increasing. The lack of educated professionals in special care dentistry is leading to severe and untreated systemic and oral health problems in the special needs population. The implementation of interprofessional treatment for special needs individuals has proven to be the most effective method of treatment within the special needs population. This study examines the current application of special care …

Examining The Psychological Adjustments Of Neurotypical Siblings Of Individuals With Autism Spectrum Disorder (Asd) And Determining The Efficiency Of Support Groups, Swathi Deo Sambatha

Undergraduate Research Posters

Neurotypical siblings of individuals with behavioral disorders are reported to have complex, complicated psychological adjustments that vary significantly due to a multitude of sociodemographic factors. In addition, these children are at risk of mental health disorders and negative psychological symptoms. Support groups or extensive social support are known to increase intra-communication and create better sibling dynamics between the neurotypical and autistic siblings. This paper investigates such complications to the psychological adjustment of neurotypical siblings of individuals with autism spectrum disorder (ASD) and determines the implications of the utilization of support groups/social support. The analyzed trends and reportings of multiple studies …

Can A Metallated Cyclen Species Be Used To Prepare New Odorants?, Jalynn Taylor-Farmer

Undergraduate Research Posters

Scientists in the fragrance industry are constantly searching for new odors to create as well as new, more efficient processes to create them. Scientists mainly look for new ways to synthesize fragrances that will reduce the impact on the environment, produce them at lower costs, produce higher yields, and sometimes to produce a more potent odor [4]. In this research, we investigated the use of metallic macrocycles and/or metal-dioxygen chemistry to prepare new fragrances.

Cyclen (1,4,7,10-tetraazacyclododecane) has significant uses in many pharmaceutical and medicinal research developments such as advances in targeted cancer and Alzheimer’s agents. Macrocyclic amines like cyclen are …

Depression Intervention Programs In Low-Income High Schools, Gopika Hari

Undergraduate Research Posters

It is estimated that 2.6 million adolescents suffer from major depressive episodes each year. Research has noted that symptoms in youth have become indicators of mental health complications later in life. Studies reveal that low income is a risk factor for depression and that socioeconomically-disadvantaged teenagers are more than twice as likely to develop mental illnesses. Only roughly 25% of children with mental illnesses receive adequate help and 80% of these resources come from schools. This study focuses on establishing the importance of depression intervention programs in low-income high schools and on designing novel guidelines for effective protocols. A compilation …

Stall Seat Journal As A Social Norms Intervention For Risky Drinking Among College Students, Zackaria I. Niazi, Mariam Alshagra, Rhianna G. Ericson, Jinni Su Ph.D., Linda C. Hancock Ph.D.

Undergraduate Research Posters

Alcohol use is prevalent among college students and many participate in risky drinking behaviors over the course of their college careers, leading to negative consequences. The social norms theory posits that individuals behave based on their perceptions of peer behavior. Overestimation of peers’ problem behavior is associated with increase in their own problem behavior. The Stall Seat Journal (SSJ), developed by the Wellness Resource Center, is used in part to help correct common misperceptions, including those related to peer alcohol use. Our study aimed to see if Stall Seat Journal readership was associated with perception of peer alcohol use among …

Potential For Aerobic Exercise To Release Growth Factors To Induce Cognitive Changes In Children With Autism Spectrum Disorder, Maya Harrington

Undergraduate Research Posters

Autism Spectrum Disorder (ASD) is becoming increasingly prevalent among adolescents, and while the number of individuals diagnosed with the disorder grows, there continues to be no cure or even a clear treatment path for ASD. This study analyzes the biological stimulations that create cognitive changes—which are induced by intensive aerobic exercise—within the brains of individuals ages 8-18 diagnosed with autism. I studied journal articles on the current treatments available for ASD, the increasing prevalence of the disease, the cognitive alterations of the autistic brain relative to the brains of individuals without the disease, the release of growth factors due to …

The Impact Of Urbanization On Mosquito-Borne Viruses, Nikhita Puthuveetil

Undergraduate Research Posters

Mosquito-borne diseases such as yellow fever, dengue, and West Nile are rapidly emerging across the globe. Their emergence is often aided by the growth of their vector population, or the organisms that transmit the virus to the host. Urbanization and land use often destroys the habitat of the virus and its vector. However, the virus and its vector often survive despite the changes to its environment. The goal of this paper is to find out exactly how urbanization and changes in land use affect mosquito-borne viruses and how these viruses survive despite the destruction of their habitats. To understand how …

The Relationship Between Exercise And Depression And Anxiety In College Students, Joshua Frank, Dr. Amy Adkins, Nathan Thomas, Dr. Danielle Dick

Undergraduate Research Posters

The literature shows an inverse association between exercise and mental disorders. The aim of this study is to further elaborate on this association with regards to exercise and its relationship with anxiety and depression in a college sample. The subject group focused on seniors in the Spit for Science data set which incorporated a total of 821 students. Physical activity was assessed using the International Physical Activity Questionnaire (IPAQ) to estimate the overall metabolic equivalents (MET’s) each student spent in walking, moderate, or vigorous activity levels in the previous week. Sum scores were used to measure depression and anxiety. Overall,the …

Healthcare Access In Women’S Prisons: An Intersectional Perspective, Megan R. Bray

Undergraduate Research Posters

This project will be identifying the key factors that contribute to the significant lack of health care in prisons in the U.S., specifically in women’s correctional facilities. I will be lending my focus to disparities in mental health, HIV/AIDs care, reproductive health, trans health, and physical health issues among women who are either currently incarcerated or those who have completed their sentences and are at higher risk for re-entry after attempting re-integration. There is a lack of care, access, and proper treatment for women inmates in U.S. prisons and reform is needed. I foresee the best possible way to accomplish …

Socioeconomic Factors Associated With Cataract-Related Blindness Treatment In Women In Rural Regions Of Andhra Pradesh, Kiranpreet Kaur 4198353

Undergraduate Research Posters

Despite efforts of Vision 2020 in India, the Andhra Pradesh Eye Disease Study (APEDS) extrapolated, in 2000, approximately 18.7 million blind people in India and also, projected an increase to 31.6 million blind people by 2020. Within the state Andhra Pradesh itself, preventable corneal blindness increased to 1.84% from 1.5% in the late 1980s.

Numerous public health studies have been conducted to outline factors that cause and preclude treatment of avoidable corneal blindness in the India. Conclusively, the escalation of corneal blindness can be largely attributed to personal, social, and economic barriers in utilizing available eye-care services. However, due to …

Perceptions Of Harm And Addiction Among Dual Users Of Cigarettes And E-Cigarettes, Julia S. Rozman

Undergraduate Research Posters

Background: Tobacco harm perceptions are important factors in why individuals may initiate, substitute, and/or engage in dual or poly-tobacco use patterns. Identifying correlates of these perceptions is important for understanding why these cognitions may exist and help provide intervention targets. The purpose of the current study was to examine perceptions of harm and addiction among a sample of cigarette and electronic cigarette (e-cigarette) users and examine whether these perceptions differ by demographics, other substance use, and tobacco use history.

Methods: The current sample consisted of 29 individuals who consented to participate in a clinical laboratory study of dual cigarette and …

An Investigation Of The Influence Of Current Public Health Policies In The United States On The Prevalence Of Rural Health Professional Shortage Areas, Hayne Noh

Undergraduate Research Posters

The healthcare professional shortage or maldistribution severely limits access to sufficient health care, affecting many Americans, particularly in rural areas. There is a range studies that agree that the health professional shortage is a pressing issue, but none that specifically evaluate the overall effectiveness and improvements to be made to government funded programs, such as Loan repayment and scholarship programs aimed at attracting primary care physicians to these rural underserved areas. This study analyzes both quantitative and qualitative data from 21 peer-reviewed journals about rural primary Health Professional Shortage Areas, Title-VII funded schools, and rural primary health care. Although effective …

Effects Of Hiv And Drugs Of Abuse On The Blood-Brain Barrier, Gopika Hari

Undergraduate Research Posters

Despite effective systemic therapy, HIV-1 infection within the brain results in neuronal degradation and neurocognitive dysfunction. This neurocognitive dysfunction is worsened in the setting of opiate abuse. The central nervous system (CNS) is protected by the blood-brain barrier (BBB), a selective barrier regulating the passage of substances from peripheral circulation into the CNS. The BBB is composed of microvascular endothelial cells encased by basal lamina, pericytes, and perivascular astrocyte endfeet. Intracellular junctional complexes comprising of adherens and tight junctions are located between the endothelial cells and form tight barrier, preventing traffic of compounds between cells (paracellular flux). Clinical and in …