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Utah State University

Autoimmune diseases

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Nutritional Perspective Of Systemic Lupus Erythematosus, Jessianna Rose May 2006

Nutritional Perspective Of Systemic Lupus Erythematosus, Jessianna Rose

Undergraduate Honors Capstone Projects

Systemic Lupus Erythematosus (SLE) is a chronic, incurable, autoimmune disease that affects as many as two million persons in the United States. Current nutritional guidelines are very basic and revolve around specifics of the treatment of symptoms as seen with drug-nutrient interactions. Although current opinion does not directly see the onset of this disease linked to dietary factors, recent research may indicate that there is a link to a possible deficiency of pantothenic acid. This is not a widely accepted theory, but has some very unique observations which shed a new and interesting light on possible interventions through nutrition.


Single Nucleotide Polymorphism (Snp) Analysis Of Tumor Necrosis Factor (Tnf)-Α In Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections (Pandas) Subjects, Corinna Wilhelmina Vonniederhausern May 2003

Single Nucleotide Polymorphism (Snp) Analysis Of Tumor Necrosis Factor (Tnf)-Α In Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections (Pandas) Subjects, Corinna Wilhelmina Vonniederhausern

Undergraduate Honors Capstone Projects

In an ongoing research project, the Center for Persons with Disabilities at Utah State University, in collaboration with Dr. Susan E. Swedo at the National Institute of Mental Health, is evaluating genetic factors affecting the development of PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections). PANDAS is manifested in a group of prepubertal children who develop obsessive-compulsive disorder (OCD) following infection with Group A beta-hemolytic Streptococcal (GABHS) bacteria. We are assessing single nucleotide polymorphisms (SNPs) in the promoter region of tumor necrosis factor (TNF)-α and other cytokines known to be important in autoimmune diseases.