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Validating Resonance Raman Spectroscopy: A Non-Invasive Assessment Of Skin Carotenoids As A Biomarker Of Fruit And Vegetable Intake In Children, Sheryl Swain Aguilar
Validating Resonance Raman Spectroscopy: A Non-Invasive Assessment Of Skin Carotenoids As A Biomarker Of Fruit And Vegetable Intake In Children, Sheryl Swain Aguilar
All Graduate Plan B and other Reports, Spring 1920 to Spring 2023
Background: Adult studies have found a strong correlation between serum carotenoids and skin carotenoids measured by resonance Raman spectroscopy (RRS). No published studies have examined correlations between skin and serum carotenoids among children.
Objectives: (1) To validate skin RRS methodology against serum carotenoid measurements by high-performance liquid chromatography and (2) to determine if RRS skin carotenoids can be used as a valid biomarker of total fruit and vegetable (FV) intake among children.
Design: Participants were 45 healthy children age 5-17 who provided 3 blood samples used to assess serum carotenoid concentrations and 3 RRS skin measurements (using a Biophotonic ScannerTM) …