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Full-Text Articles in Medicine and Health Sciences

An Investigation Of In Vitro Percutaneous Penetration Enhancement Of Benzocaine By Azone, Dimethylsulfoxide, And 2-Pyrrolidone, Amal Y. Benkorah Jan 1986

An Investigation Of In Vitro Percutaneous Penetration Enhancement Of Benzocaine By Azone, Dimethylsulfoxide, And 2-Pyrrolidone, Amal Y. Benkorah

University of the Pacific Theses and Dissertations

This research utilizing full thickness human abdominal skin was designed to assess the in vitro percutaneous penetration of benzocaine by 1-dodecylazacycloheptan-2-one (Azone) , dimethylsulfoxide (DMSO) and 2-pyrrolidone (2-P) under conditions of constant thermodynamic activity in the vehicle. The solubilities of benzocaine in Azone and 80/20, 60/40 and 40/60 V/V DMSO/water systems were found to be 254.17, 533.00, 68.60 and 2.51 mg/ml respectively. All three adjuvants demonstrated a significant but concentration- dependent enhancement of benzocaine penetration. On the basis of comparative analysis of the steady-state fluxes, Azone was most effective at the level of 5% V/V when drug concentration was twice …


Care During Death, Grief And Loss: The Effects Of A Workshop And Clinical Experience On Student Nurses' Attitudes And Actions, Lynda Armstrong Wilson Jan 1986

Care During Death, Grief And Loss: The Effects Of A Workshop And Clinical Experience On Student Nurses' Attitudes And Actions, Lynda Armstrong Wilson

University of the Pacific Theses and Dissertations

Problem. Nurses, members of a society which tends to avoid and deny death, grief, and loss, are frequently in situations where they must interact with persons experiencing grief from death or loss. Often educational experiences have done little to prepare student nurses to cope in positive and supportive ways. Student nurses need to develop self-awareness of their attitudes and anxieties toward death, loss, and grief; modify negative attitudes; and develop a repertoire of interpersonal skills to support persons experiencing grief. Purpose. The purpose of this study was to determine if academic, and experiential learning could influence the clinical performance of …


Factors Associated With The Clinical Outcome And Nephrotoxicity In Patients Treated With Gentamicin, Wen-Hwei Chen Jan 1986

Factors Associated With The Clinical Outcome And Nephrotoxicity In Patients Treated With Gentamicin, Wen-Hwei Chen

University of the Pacific Theses and Dissertations

This study is designed to investigate via discriminant analysis the factors that are associated with the clinical outcome and nephrotoxicity in patients receiving gentamicin.


The Effects Of Health Related Feedback On A Smoking Cessation Maintenance Program, Janice A. Blalock Jan 1986

The Effects Of Health Related Feedback On A Smoking Cessation Maintenance Program, Janice A. Blalock

University of the Pacific Theses and Dissertations

The present study investigated the effectiveness of health related feedback as a positive reinforcer of abstinence from smoking during the 11 week period following cessation. Fifty-three subjects were randomly assigned to one of three groups: (a) maintenance program plus health related feedback (MF), (b) maintenance program only (M) and, (c) discussion control (D). All groups received an aversive treatment for smoking after which the MP group received coping skills raining and several forms of health related feedback, the M group received coping skills training only, and the D group received discussion. Groups did not differ significantly in abstinence at each …


The Partial Purification And Characterization Of A Soluble Activator For The Sodium Adenosinetriphosphatase From Rat Cerebral Cortex And The Effect Of Cholinergic Agents, Thibaldo Javier Manrique Blanco Jan 1986

The Partial Purification And Characterization Of A Soluble Activator For The Sodium Adenosinetriphosphatase From Rat Cerebral Cortex And The Effect Of Cholinergic Agents, Thibaldo Javier Manrique Blanco

University of the Pacific Theses and Dissertations

In order for organisms to co-exist with nonliving matter, envelop to protect their delicate internal functions must be present. There are other reasons for this boundary to exist, e.g. to limit the volume occupied by the organism and to compartmentalize the contents of the organism so that certain critical concentrations may be easily maintained. Such envelopes are, of course, the cellular membranes. Membranes differ greatly between species, as well as within species. Given the complexity to which organisms have evolved, membranes have developed with a myriad of functions and components. It is easy to see differences between plant cellular membranes …


A Comparative Study Of Positive Versus Negative Polarity In The Treatment Of Acute Ankle Sprains Utilizing High Voltage Electrogalvanic Stimulation, Lauren Michelle Wells Jan 1986

A Comparative Study Of Positive Versus Negative Polarity In The Treatment Of Acute Ankle Sprains Utilizing High Voltage Electrogalvanic Stimulation, Lauren Michelle Wells

University of the Pacific Theses and Dissertations

Electrical stimulation has long been used in the treatment of a variety of ailments. Its current uses range from muscle re-education and orthotic substitute to scoliosis management and edema control. I chose to study the effect of electrode polarity in high voltage electrogalvanic stimulation in the treatment of edema for several reasons. I had access to subjects because I was the only physical therapist at the Stockton Orthopedic Medical Group. High voltage electrogalvanic stimulation is a commonly used modality in treating edema (Brown, 1981). High voltage generators have a polarity switch, and the direction manual which accompanies the Electro-Med generator …


Reduction Of Stuttering In Adult Males Using Relaxed Breathing And Emg Biofeedback : A Masters Thesis ..., Victor F. Corsiglia Jan 1986

Reduction Of Stuttering In Adult Males Using Relaxed Breathing And Emg Biofeedback : A Masters Thesis ..., Victor F. Corsiglia

University of the Pacific Theses and Dissertations

The present study trained three adult male stutterers to increase speech fluency using relaxed breathing and a-x; biofeedback. A one group time-series design with 2 treatments was used. After an initial baseline phase (A) all 3 subjects received a relaxed breathing procedure (B), followed by a combined procedure featuring relaxed breathing and EMG biofeedback (BC). Results indicated that after 8 sessions stuttering was reduced by 19.1% from baseline levels across the 3 subjects. Despite these promising results , however, methodological questions in the baseline phase make conclusions regarding a clear relationship between the variables tentative.