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Full-Text Articles in Medicine and Health Sciences
The Management Of Tricyclic Antidepressant Poisoning: The Role Of Gut Decontamination, Extracorporeal Procedures And Fab Antibody Fragments, Paul I. Dargan, Mark G. Colbridge, Alison Jones
The Management Of Tricyclic Antidepressant Poisoning: The Role Of Gut Decontamination, Extracorporeal Procedures And Fab Antibody Fragments, Paul I. Dargan, Mark G. Colbridge, Alison Jones
Graduate School of Medicine - Papers (Archive)
Although there have been descriptive, uncontrolled clinical reports of removal of tablet debris by gastric lavage, there have been no clinical studies that have demonstrated that this has any impact on outcome in patients with tricyclic antidepressant (TCA) poisoning. There is also the possibility that lavage may increase drug absorption by pushing tablets into the small intestine. Furthermore, gastric lavage in patients with TCA poisoning may induce hypoxia and a tachycardia potentially increasing the risk of severe complications such as arrhythmias and convulsions. In view of the paucity of evidence that gastric lavage removes a significant amount of drug and …
Asthma And Depression: A Pragmatic Review Of The Literature And Recommendations For Future Research, Melissa Opolski, Ian Wilson
Asthma And Depression: A Pragmatic Review Of The Literature And Recommendations For Future Research, Melissa Opolski, Ian Wilson
Graduate School of Medicine - Papers (Archive)
Background: Although the association between asthma and psychosocial factors has long been recognised, it is only in the last decade that the impact of coexisting asthma and depression has become the focus of considerable research interest. However, the findings so far have been confusing and often contradictory. This paper sets out a methodical review and appraisal of the literature to date, including suggestions for future research. Method: PubMed and PsycINFO databases were used to search for English-language articles relating to asthma and depression research. The resulting articles were then reviewed and summarised, creating a report that was used to develop …