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Full-Text Articles in Medicine and Health Sciences
Serotypes And Virulence Gene Profiles Of Shiga Toxin-Producing Escherichia Coli Strains Isolated From Feces Of Pasture-Fed And Lot-Fed Sheep, Steven Djordjevic, Vidiya Ramachandran, Karl A Bettelheim, Barbara A. Vanselow, Peter Holst, Graham Bailey, Michael A. Hornitsky
Serotypes And Virulence Gene Profiles Of Shiga Toxin-Producing Escherichia Coli Strains Isolated From Feces Of Pasture-Fed And Lot-Fed Sheep, Steven Djordjevic, Vidiya Ramachandran, Karl A Bettelheim, Barbara A. Vanselow, Peter Holst, Graham Bailey, Michael A. Hornitsky
Faculty of Science, Medicine and Health - Papers: part A
Shiga toxin-producing Escherichia coli (STEC) strains possessing genes for enterohemolysin (ehxA) and/or intimin (eae), referred to here as complex STEC (cSTEC), are more commonly recovered from the feces of humans with hemolytic uremic syndrome and hemorrhagic colitis than STEC strains that do not possess these accessory virulence genes. Ruminants, particularly cattle and sheep, are recognized reservoirs of STEC populations that may contaminate foods destined for human consumption. We isolated cSTEC strains from the feces of longitudinally sampled pasture-fed sheep, lot-fed sheep maintained on diets comprising various combinations of silage and grain, and sheep simultaneously grazing pastures …
A Mixed-Model Approach For The Analysis Of Cdna Microarray Gene Expression Data From Extreme-Performing Pigs After Infection With Actinobacillus Pleuropneumoniae, R J. Moser, A Reverter, Caroline A. Kerr, K J. Beh
A Mixed-Model Approach For The Analysis Of Cdna Microarray Gene Expression Data From Extreme-Performing Pigs After Infection With Actinobacillus Pleuropneumoniae, R J. Moser, A Reverter, Caroline A. Kerr, K J. Beh
Graduate School of Medicine - Papers (Archive)
We proposed a novel statistical approach for the analysis of cDNA experiments based on mixed-model methodology combined with mixtures of distributions. Our objective was to detect genes that may be involved in conferring heritable differences in susceptibility to common infections in intensive pig production. We employed a microarray expression profiling strategy and a mixed-model approach to the analysis of the expression data. A cDNA microarray of pig with 6,420 probes from immune tissues and cells was used to compare gene expression in peripheral blood leukocytes of two pigs showing extreme performance in their response to infection with Actinobacillus pleuropneumoniae. Principal …