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Full-Text Articles in Medicine and Health Sciences
Early Integration Of The Individual Student In Academic Activities: A Novel Classroom Concept For Graduate Education In Molecular Biophysics And Structural Biology, Sanford H. Leuba, Sean M. Carney, Elizabeth M. Dahlburg, Rebecca J. Eells, Harshad Ghodke, Naveena Yanamala, Grant Schauer, Judith Klein-Seetharaman
Early Integration Of The Individual Student In Academic Activities: A Novel Classroom Concept For Graduate Education In Molecular Biophysics And Structural Biology, Sanford H. Leuba, Sean M. Carney, Elizabeth M. Dahlburg, Rebecca J. Eells, Harshad Ghodke, Naveena Yanamala, Grant Schauer, Judith Klein-Seetharaman
Faculty of Science, Medicine and Health - Papers: part A
Background: A key challenge in interdisciplinary research is choosing the best approach from a large number of techniques derived from different disciplines and their interfaces.
Results: To address this challenge in the area of Biophysics and Structural Biology, we have designed a graduate level course to teach students insightful use of experimental biophysical approaches in relationship to addressing biological questions related to biomolecular interactions and dynamics. A weekly seminar and data and literature club are used to compliment the training in class. The course contains wet-laboratory experimental demonstration and real-data analysis as well as lectures, grant proposal preparation and assessment, …
Using Biophysics And Dynamic Energy Budget Theory To Investigate How A Large Mammal Responds To Varying Environmental Conditions, J A. Roberts, Salm Kooijman, G C. Coulson, A J. Munn, M R. Kearney
Using Biophysics And Dynamic Energy Budget Theory To Investigate How A Large Mammal Responds To Varying Environmental Conditions, J A. Roberts, Salm Kooijman, G C. Coulson, A J. Munn, M R. Kearney
Faculty of Science, Medicine and Health - Papers: part A
Abstract of paper that presented at SICB 2013 Annual Meeting.
Method For Measurement Of Viral Fusion Kinetics At The Single Particle Level, Daniel L. Floyd, Stephen C. Harrison, Antoine M. Van Oijen
Method For Measurement Of Viral Fusion Kinetics At The Single Particle Level, Daniel L. Floyd, Stephen C. Harrison, Antoine M. Van Oijen
Faculty of Science, Medicine and Health - Papers: part A
Membrane fusion is an essential step during entry of enveloped viruses into cells. Conventional fusion assays typically report on a large number of fusion events, making it difficult to quantitatively analyze the sequence of the molecular steps involved. We have developed an in vitro, two-color fluorescence assay to monitor kinetics of single virus particles fusing with a target bilayer on an essentially fluid support. Influenza viral particles are incubated with a green lipophilic fluorophore to stain the membrane and a red hydrophilic fluorophore to stain the viral interior. We deposit a ganglioside-containing lipid bilayer on the dextran-functionilized glass surface of …