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Full-Text Articles in Medicine and Health Sciences
Can Genetic Factors Compromise The Success Of Dental Implants? A Systematic Review And Meta-Analysis, Joel Ferreira Santiago Junior, Cláudia Cristina Biguetti, Mariza Akemi Matsumoto, Guilherme Abu Halawa Kudo, Raquel Barroso Parra Da Silva, Patrícia Pinto Saraiva, Walid D. Fakhouri
Can Genetic Factors Compromise The Success Of Dental Implants? A Systematic Review And Meta-Analysis, Joel Ferreira Santiago Junior, Cláudia Cristina Biguetti, Mariza Akemi Matsumoto, Guilherme Abu Halawa Kudo, Raquel Barroso Parra Da Silva, Patrícia Pinto Saraiva, Walid D. Fakhouri
School of Podiatric Medicine Publications and Presentations
Dental implants provide a predictable treatment option for partial and complete edentulism via the placement of a fixed permanent artificial root to support prosthetic dental crowns. Despite the high survival rates, long-term dental implant failures are still reported, leading to implant removals and additional financial and health burdens. While extrinsic factors that improve the success rate of implants have been well explored, the impact of genetic factors on this matter is poorly understood. A systematic review and meta-analysis study was conducted to determine whether genetic factors contribute to an increased risk of dental implant failures. A comprehensive search for peer-reviewed …
Oral Implant Osseointegration Model In C57bl/6 Mice: Microtomographic, Histological, Histomorphometric And Molecular Characterization, Cláudia Cristina Biguetti, Franco Cavalla, Elcia Varize Silveira, Angélica Cristina Fonseca, Andreia Espindola Vieira, Andre Petenucci Tabanez, Danieli C. Rodrigues, Ana Paula Favaro Trombone, Gustavo P. Garlet
Oral Implant Osseointegration Model In C57bl/6 Mice: Microtomographic, Histological, Histomorphometric And Molecular Characterization, Cláudia Cristina Biguetti, Franco Cavalla, Elcia Varize Silveira, Angélica Cristina Fonseca, Andreia Espindola Vieira, Andre Petenucci Tabanez, Danieli C. Rodrigues, Ana Paula Favaro Trombone, Gustavo P. Garlet
School of Podiatric Medicine Publications and Presentations
Introduction: Despite the successful clinical application of titanium (Ti) as a biomaterial, the exact cellular and molecular mechanisms responsible for Ti osseointegration remains unclear, especially because of the limited methodological tools available in this field.
Objective: In this study, we present a microscopic and molecular characterization of an oral implant osseointegration model using C57Bl/6 mice.
Material and methods: Forty-eight male wild-type mice received a Ti implant on the edentulous alveolar crest and the peri-implant sites were evaluated through microscopic (μCT, histological and birefringence) and molecular (RealTimePCRarray) analysis in different points in time after surgery (3, 7, 14 and 21 days). …