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Full-Text Articles in Medicine and Health Sciences
Tgf-Β Signaling Pathways In The Development Of Diabetic Retinopathy, Andrew Callan, Sonal V. Jha, Laura Garcia, Lois F. Baldado, Andrew Tsin
Tgf-Β Signaling Pathways In The Development Of Diabetic Retinopathy, Andrew Callan, Sonal V. Jha, Laura Garcia, Lois F. Baldado, Andrew Tsin
School of Medicine Publications and Presentations
Diabetic retinopathy (DR), a prevalent complication of diabetes mellitus affecting a significant portion of the global population, has long been viewed primarily as a microvascular disorder. However, emerging evidence suggests that it should be redefined as a neurovascular disease with multifaceted pathogenesis rooted in oxidative stress and advanced glycation end products. The transforming growth factor-β (TGF-β) signaling family has emerged as a major contributor to DR pathogenesis due to its pivotal role in retinal vascular homeostasis, endothelial cell barrier function, and pericyte differentiation. However, the precise roles of TGF-β signaling in DR remain incompletely understood, with conflicting reports on its …
Improving Inpatient Hyperglycaemia In Non-Critically Ill Adults In Resident Wards Through Audit And Feedback, Chelsea H. Chang, Alcibiades Fleires, Alfarooq Alshaikhli, Hector Arredondo, Diana Gavilanes, Francisco J. Cabral-Amador, Jonathon Cantu, Daniela Bazan, Kathryn Oliveira Oliveira, Rene Verduzco, Lina Pedraza Sanchez
Improving Inpatient Hyperglycaemia In Non-Critically Ill Adults In Resident Wards Through Audit And Feedback, Chelsea H. Chang, Alcibiades Fleires, Alfarooq Alshaikhli, Hector Arredondo, Diana Gavilanes, Francisco J. Cabral-Amador, Jonathon Cantu, Daniela Bazan, Kathryn Oliveira Oliveira, Rene Verduzco, Lina Pedraza Sanchez
School of Medicine Publications and Presentations
Inpatient hyperglycaemia is associated with an increase in morbidity and mortality, number of rehospitalisations and length of hospitalisation. Although the advantages of proper glycaemic control in hospitalised patients with diabetes are well established, a variety of barriers limit accomplishment of blood glucose targets. Our primary aim was to decrease the number of glucose values above 180 mg/dL in non-critical care hospitalised patients using an audit and feedback intervention with pharmacy and internal medicine residents. A resident-led multidisciplinary team implemented the quality improvement (QI) project including conception, literature review, educating residents, iterative development of audit and feedback tools and data analysis. …