Medicine and Health Sciences Commons^™

Protein Expression Of G-Protein Inwardly Rectifying Potassium Channels (Girk) In Breast Cancer Cells, Madhu S. Dhar, Howard K. Plummer

Faculty Publications and Other Works -- Large Animal Clinical Sciences

Background

Previous data from our laboratory has indicated that a functional link exists between the G-protein-coupled inwardly rectifying potassium (GIRK) channel and the beta-adrenergic receptor pathway in breast cancer cell lines, and these pathways were involved in growth regulation of these cells. Alcohol is an established risk factor for breast cancer and has been found to open GIRK. In order to further investigate GIRK channels in breast cancer and possible alteration by ethanol, we identified GIRK channel protein expression in breast cancer cells.

Results

Cell pellets were collected and membrane protein was isolated to determine GIRK protein expression. GIRK protein …

Counteracting Muscle Wasting In Hiv-Infected Individuals, Kenneth D. Phillips

Faculty Publications and Other Works -- Nursing

No abstract provided.

Spiritual Well-Being, Sleep Disturbance And Mental And Physical Health Status In Hiv-Infected Individuals, Kenneth D. Phillips

Faculty Publications and Other Works -- Nursing

No abstract provided.

Alcohol And Other Drug Disorders, Comorbidity And Violence In Rural African American Women, Kenneth D. Phillips

Faculty Publications and Other Works -- Nursing

No abstract provided.

Inflammatory And Immune System Correlates Of Rape, M.W. Groer, Sandra Thomas, G.W. Evans, S. Helton

Faculty Publications and Other Works -- Nursing

The purpose of this study was to evaluate the feasibility of measuring stress hormones and immunity following rape. The long-term goal is to evaluate the predictive value of stress-immune-inflammatory responses to later health outcomes. Fifteen women reporting rape were compared with 16 control participants. Serum stress hormones, proinflammatory cytokines, acute phase proteins, functional assays, and lymphocyte subsets were measured in blood samples. Women reporting rape had higher cytotoxic cells, lower B lymphocyte counts, higher proinflammatory biomarkers, and decreased lymphocyte proliferation compared to the control group. This finding suggests that rape produces activation of the innate immunity and suppression of some …

Nurses' Narratives Of Unforgettable Patient Care Events, M.E. Gunther, Sandra Thomas

Faculty Publications and Other Works -- Nursing

Purpose: To explore the experience of registered nurses (RNs) caring for patients in contemporary hospitals. Design: The descriptive phenomenological study was based in the philosophical perspectives of Husserl and Merleau-Ponty. Methods: A purposive sample of 46 RNs employed in acute care hospitals in the southeastern United States (US) were recruited by network sampling. Data from unstructured interviews were analyzed in an interpretive group and themes were identified. Findings: Four themes were identified: (a) extraordinary caregiving events, (b) incomprehensibility, (c) questioning whether anything else could have been done, and (d) “alone or together,” indicating the isolation nurses often experience while giving …

Predictors Of Quality Of Life In Hiv-Infected Rural Women: Psychometric Test Of The Chronic Illness Quality Of Life Ladder, C. Murdaugh, L. Moneyham, K. Jackson, Kenneth D. Phillips, A. Tavakoli

Faculty Publications and Other Works -- Nursing

The Chronic Illness Quality of Life Ladder (CIQOLL) underwent psychometric testing in a sample of 278 women with HIV disease. The CIQOLL, a self-anchoring striving scale based on Cantril’s Ladder, measures seven domains (physical , emotional, financial, family and friends, spiritual well-being, peace of mind, and overall life satisfaction) across four time periods (present, past, future, life without a diagnosis of HIV). The domains were derived from focus groups with persons with HIV disease. Women with a diagnosis of HIV Infection, age 18 or older, residing in rural areas in the southeastern United States, completed questionnaires that measured physical functioning, …

Talking It Over With The Gals: An Analysis Of Editorials By Phyllis Stern, Sandra Thomas

Faculty Publications and Other Works -- Nursing

Editorials written by a journal editor proved a glimpse of that individual's philosophy and opinions about topical events. The purpose of the present project was to analyze the editorials of Phyllis Noerager Stern during the years that she served as editor-in-chief of Health Care for Women International (1983-2001). Using ethnographic content analysis, 65 editorials were examined to ascertain: (1) what event triggered the editorial; (2) what aim or objective could be identified; and (3) what rhetorical devices the editor employed. Personal narratives and editorials about the abuse/exploitation of women made up the largest categories. Stern's grounded theory orientation, fascination with …

Frontiers (Anniversary Edition 2006) - Celebrating 50 Years, University Of Tennessee Medical Center, University Of Tennessee Graduate School Of Medicine

Frontiers Magazine

No abstract provided.

Frontiers (1st Quarter 2006) - Books For Children; Becoming A Doctor; Surviving A Heart Attack, University Of Tennessee Medical Center, University Of Tennessee Graduate School Of Medicine

Frontiers Magazine

No abstract provided.

Frontiers (4th Quarter 2006) - A Focus On Women's Healthcare: It's Not Just Delivering Babies Anymore, University Of Tennessee Medical Center, University Of Tennessee Graduate School Of Medicine

Frontiers Magazine

No abstract provided.

Frontiers (2nd Quarter 2006) - Trauma, There Are No Accidents; Fellowships; Lifestar, University Of Tennessee Medical Center, University Of Tennessee Graduate School Of Medicine

Frontiers Magazine

No abstract provided.

Volume 4, Number 1 (2006), Ut Institute Of Agriculture

Tennessee Land, Life and Science Magazine

Issue Highlights:

• A focus on agriculture and natural resources programs at the University of Tennessee Institute of Agriculture

Volume 4, Number 2 (2006), Ut Institute Of Agriculture

Tennessee Land, Life and Science Magazine

Issue Highlights:

• From Grow to Go for a New Bioeconomy