Medicine and Health Sciences Commons^™

Muscle Fiber Size And Composition Differences Between Ames Dwarf Mice And Wild-Type Mice, Jordan Anderson

Physical Therapy Scholarly Projects

Background: Ames dwarf mice demonstrate delayed aging processes in multiple body systems. We compared muscle composition and area between dwarf and wild-type mice to determine if any significant differences exist.

Methods: We resected soleus, gastrocnemius/plantaris, tibialis anterior, and extensor digitorum longus muscles from both dwarf and wild-type mice, then froze, sliced, set on slides, and stained to isolate fast-twitch and slow-twitch fibers. Microscopy images were taken at 10x magnification and fiber composition and cross-sectional area were measured in soleus muscles.

Results: Wild-type mice had an average composition of 52.3% fast-twitch and 47.7% slow-twitch fibers while dwarf mice had 66.3% slow-twitch …

Effectiveness Of Physical Therapy Intervention Following Partial Medial Meniscectomy: A Case Report, Alexa Risan

Physical Therapy Scholarly Projects

Background and Purpose. Partial meniscectomy is a very commonly performed surgical procedure and many cases are uncomplicated and successfully treated with home-based exercise programs. However, some patients experience more significant problems following surgery and require rehabilitation services. Research is limited regarding physical therapy (PT) effectiveness in the post-operative management of such complicated cases. This case report aims to evaluate the effectiveness of PT treatment of a 34-year-old male with significant impairments and functional limitations following partial medial meniscectomy.

Case Description. Examination and evaluation included ROM/flexibility and strength measurements as well as functional assessment. PT included therapeutic exercise which was aimed …

Sarcopenia And Current Research Using Ames Dwarf Mice: A Research Study, Amanda Sodemann

Physical Therapy Scholarly Projects

This research project focused on the differences observed in muscle fiber composition and surface area between wild type mice and Ames dwarf mice as they aged. A mouse model was utilized because the skeletal muscle framework of mice closely resembles that of human muscle; thus, the observations seen within the mice may also be seen within humans as they age. Comparisons between the wild type and dwarf mice include a smaller cross-sectional muscle area in a dwarf mouse and no drastic change in the percentages of fast and slow twitch muscle fibers as the dwarf mouse ages. Furthermore, differences in …

S/P Right Hip Orif, Brian Bartow

Physical Therapy Scholarly Projects

Background and Purpose: Hip fracture is a major medical problem among older adults, leading to impaired balance and gait and loss of functional independence. An open reduction internal fixation (ORIF) is a method of surgically repairing a fractured bone. Generally, this involves either the use of plates and screws or an intramedullary (IM) rod to stabilize the bone.

Case Description: The patient was a 51-year-old female who fractured her right hip while running. She had complained of thigh pain with running for 1 to 2 months prior. She had gamma nail pinning.

Intervention: The focus of treatment was to increase …

Cervical Radiculopathy: A Case Report, Kimberly Dobrovolny

Physical Therapy Scholarly Projects

There is currently little evidence to determine which conservative treatment approach is best for the management of patients with cervical radiculopathy; however, there is evidence these patients benefit from a multi-treatment approach. The purpose of this case is to describe the physical therapy management of a patient with cervical radiculopathy. Physical therapy diagnosis was based on the patient’s physical signs and symptoms as well as meeting three of the four criteria of the clinical prediction rule which is used to identify patients with cervical radiculopathy. Results from the examination and evaluation were consistent with the magnetic resonance imaging findings. Physical …