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Breast Conserving Therapy Vs Mastectomy In Treatment Of Early Breast Cancer Patients. Does Brca1/Brca2 Status Change Treatment Recommendations?, Kylie Engebretson

Physician Assistant Scholarly Project Papers

In the United States, breast cancer is the second most common cancer, represents 30% of total cancer cases and 14% of deaths in the United States in 2019. BRCA1 and BRCA2 are genetic mutations that increase the likelihood of developing breast cancer by 57% and 49%, respectfully. Several surgical options are available for those with newly diagnosed early-stage breast cancer. The purpose of this systemic literature review is to evaluation the safety and efficacy of breast conserving therapy versus mastectomy for surgical intervention of early-stage breast cancer patients and evaluate if possessing a BRCA positive mutation changes the recommendation for …