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Full-Text Articles in Medicine and Health Sciences
Hyperbaric Oxygen Therapy For Alzheimer’S Dementia With Positron Emission Tomography Imaging: A Case Report, Paul G. Harch, Edward F. Fogarty
Hyperbaric Oxygen Therapy For Alzheimer’S Dementia With Positron Emission Tomography Imaging: A Case Report, Paul G. Harch, Edward F. Fogarty
Radiology Faculty Publications
A 58-year-old female was diagnosed with Alzheimer’s dementia (AD) which was rapidly progressive in the 8 months prior to initiation of hyperbaric oxygen therapy (HBOT). 18Fluorodeoxyglucose (18FDG) positron emission tomography (PET) brain imaging demonstrated global and typical metabolic deficits in AD (posterior temporal-parietal watershed and cingulate areas). An 8-week course of HBOT reversed the patient’s symptomatic decline. Repeat PET imaging demonstrated a corresponding 6.5–38% regional and global increase in brain metabolism, including increased metabolism in the typical AD diagnostic areas of the brain. Continued HBOT in conjunction with standard pharmacotherapy maintained the patient’s symptomatic level of function over an ensuing …
Subacute Normobaric Oxygen And Hyperbaric Oxygen Therapy In Drowning, Reversal Of Brain Volume Loss: A Case Report, Paul G. Harch, Edward F. Fogarty
Subacute Normobaric Oxygen And Hyperbaric Oxygen Therapy In Drowning, Reversal Of Brain Volume Loss: A Case Report, Paul G. Harch, Edward F. Fogarty
Radiology Faculty Publications
A 2-year-old girl experienced cardiac arrest after cold water drowning. Magnetic resonance imaging (MRI) showed deep gray matter injury on day 4 and cerebral atrophy with gray and white matter loss on day 32. Patient had no speech, gait, or responsiveness to commands on day 48 at hospital discharge. She received normobaric 100% oxygen treatment (2 L/minute for 45 minutes by nasal cannula, twice/day) since day 56 and then hyperbaric oxygen treatment (HBOT) at 1.3 atmosphere absolute (131.7 kPa) air/45 minutes, 5 days/week for 40 sessions since day 79; visually apparent and/or physical examination-documented neurological improvement occurred upon initiating each …