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New Ways Of Predicting Efficacy Of Antidepressants, Kayla Ternes Jan 2018

New Ways Of Predicting Efficacy Of Antidepressants, Kayla Ternes

Physician Assistant Scholarly Project Papers

Major depressive disorder (MDD) is a neuropsychiatric condition that is becoming increasingly prevalent in our country. According to Cai, Huang, and Hao (2015), MDD is “common and devastating” (p. 61) and has a very complex pathophysiology. Until recently, a definitive etiology had not been found, however, new evidence has suggested that Brain-derived neurotrophic factor (BDNF) and cognitive-emotional biomarkers may be a key into the mechanism of this disorder.

My literature review of articles found in PubMed, CINAHL, Cochrane Library, and PsychINFO within the last ten years focused on the hypotheses of the pathophysiology of MDD, cognitive-emotional biomarkers, and BDNF. The …


New Ways Of Predicting Efficacy Of Antidepressants, Kayla Ternes Jan 2018

New Ways Of Predicting Efficacy Of Antidepressants, Kayla Ternes

Physician Assistant Scholarly Project Posters

Major depressive disorder (MDD) is a neuropsychiatric condition that is becoming increasingly prevalent in our country. According to Cai, Huang, and Hao (2015), MDD is “common and devastating” (p. 61) and has a very complex pathophysiology. Until recently, a definitive etiology had not been found, however, new evidence has suggested that Brain-derived neurotrophic factor (BDNF) and cognitive-emotional biomarkers may be a key into the mechanism of this disorder.

A literature review of articles found in PubMed, CINAHL, Cochrane Library, and PsychINFO within the last ten years focused on the hypotheses of the pathophysiology of MDD, cognitive-emotional biomarkers, and BDNF. The …