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2021

Apolipoprotein E or APOE; Alzheimer’s disease; Hispanic; Cognitive impairment

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Apolipoprotein E And Development Of Alzheimer’S Disease In Hispanic Populations: A Scoping Review, Amy Nguyen, Stacey Moeller Apr 2021

Apolipoprotein E And Development Of Alzheimer’S Disease In Hispanic Populations: A Scoping Review, Amy Nguyen, Stacey Moeller

Undergraduate Research Symposium Posters

Alzheimer’s disease (AD) disproportionately affects Hispanic individuals, who face about 1.5- fold more risk for AD than non-Hispanic whites (NHW). Few studies examine AD biomarkers by ethnoracial group, even for the well-established susceptibility locus of apolipoprotein E (APOE). This study reviews current literature on the association between APOE and incidence of AD in Hispanic populations. A scoping review was conducted to identify publications with Hispanic study samples that examined prevalence of APOE’s three alleles (e2, e3, e4) and the risk of disease conferred by each. Two researchers combined search results from PubMed, Scopus, and APA PsycInfo databases, deleted duplicates, and …