Medicine and Health Sciences Commons^™

The Impact Of High-Intensity Interval Training On Vascular Function In Adults: A Systematic Review And Meta-Analysis, Mousa Khalafi, Mohammad Hossein Sakhaei, Fatemeh Kazeminasab, Michael E. Symonds, Sara K. Rosenkranz

Kinesiology and Nutrition Sciences Faculty Publications

Aim: We performed a systematic review and meta-analysis to investigate the effects of high-intensity interval training (HIIT) compared with moderateintensity continuous training (MICT) or with no exercise (CON) on vascular function in adults who were free of cardiometabolic diseases and those with cardiometabolic diseases.

Methods: A search across three electronic databases including Scopus, PubMed, and Web of Science was conducted through February 2022 to identify the randomized trials evaluating HIIT vs. MICT and/or CON on vascular function as measured using brachial artery flow-mediated dilation (FMD) in adults. Separate analyses were conducted for HIIT vs. MICT and/or CON to calculate weighted …

Chronotype And Social Jetlag Influence Performance And Injury During Reserve Officers’ Training Corps Physical Training, Graham Mcginnis, Shani T. Thompson, Charli D. Aguilar, Michael B. Dial, Richard Tandy, Kara N. Radzak

Kinesiology and Nutrition Sciences Faculty Publications

Sleep and circadian rhythms are critically important for optimal physical performance and maintaining health during training. Chronotype and altered sleep may modulate the response to exercise training, especially when performed at specific times/days, which may contribute to musculoskeletal injury. The purpose of this study was to determine if cadet characteristics (chronotype, sleep duration, and social jetlag) were associated with injury incidence and inflammation during physical training. Reserve Officers’ Training Corps (ROTC) cadets (n = 42) completed the Morningness/Eveningness Questionnaire to determine chronotype, and 1-week sleep logs to determine sleep duration and social jetlag. Salivary IL-6 was measured before and after …

The Effect Of Exercise Modality On Age-Related Changes Observed During Running, Brianne Borgia, Janet S. Dufek, Kara N. Radzak, Julia Freedman Silvernail

Kinesiology and Nutrition Sciences Faculty Publications

Introduction: With the increase in participation by older adults in endurance events, research is needed to evaluate how exercising throughout the lifespan can afect the aging process regarding gait and mobility. The purpose of this study was to determine how the type of exercise modality one participates in will affect age-related declines observed during running.

Methods: Fifty-six individuals between the ages of 18–65 who considered running, resistance training or cycling/ swimming as their primary form of activity participated in this study. Kinematics were captured using a 10-camera motion capture system while participants ran at a controlled pace of 3.5 m/s …

Age And Not The Preferred Limb Influences The Kinematic Structure Of Pointing Movements, Kurt W. Kornatz, Brach Poston, George E. Stelmach

Kinesiology and Nutrition Sciences Faculty Publications

In goal-directed movements, effective open-loop control reduces the need for feedback-based corrective submovements. The purpose of this study was to determine the influence of hand preference and aging on submovements during single-and two-joint pointing movements. A total of 12 young and 12 older right-handed participants performed pointing movements that involved either elbow extension or a combination of elbow extension and horizontal shoulder flexion with their right and left arms to a target. Kinematics were used to separate the movements into their primary and secondary submovements. The older adults exhibited slower movements, used secondary submovements more often, and produced relatively shorter …

Dietary Strawberries Improve Biomarkers Of Antioxidant Status And Endothelial Function In Adults With Cardiometabolic Risks In A Randomized Controlled Crossover Trial, Arpita Basu, Kenneth Izuora, Nancy M. Betts, Jeffrey L. Ebersole, Robert Hal Scofield

Kinesiology and Nutrition Sciences Faculty Publications

Strawberries, a popularly consumed berry fruit, are rich in bioactive compounds with antioxidant effects. In this study, we examined the effects of two dietary achievable doses of strawberries on the antioxidant status and biomarkers of endothelial function in adults with features of metabolic syndrome and a confirmed low baseline of fruit and vegetable intake. In a 14-week randomized controlled crossover study, participants were assigned to one of three groups for four weeks separated by a one-week washout period: control powder, one serving (low dose: 13 g strawberry powder/day), or 2.5 servings (high dose: 32 g strawberry powder/day). Blood samples and …

A Protocol And Novel Tool For Systematically Reviewing The Effects Of Mindful Walking On Mental And Cardiovascular Health, Dustin W. Davis, Bryson Carrier, Brenna Barrios, Kyle Cruz, James W. Navalta

Kinesiology and Nutrition Sciences Faculty Publications

To our knowledge, no published systematic review has described the effects of mindful walking on mental and cardiovascular health. We have aimed to fill this gap by first establishing our systematic review protocol. Our protocol was adapted from the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and is registered in PROSPERO (Registration Number: CRD42021241180). The protocol is described step-by-step in this paper, which we wrote to achieve three objectives: to adhere to the best practices stated in the PRISMA guidelines, to ensure procedural transparency, and to enable readers to co-opt our protocol for future systematic reviews on mindful …

Dietary Blueberry And Soluble Fiber Improve Serum Antioxidant And Adipokine Biomarkers And Lipid Peroxidation In Pregnant Women With Obesity And At Risk For Gestational Diabetes, Arpita Basu, Jeannette Crew, Jeffrey L. Ebersole, Jefferson W. Kinney, Arnold M. Salazar, Petar Planinic, James M. Alexander

Kinesiology and Nutrition Sciences Faculty Publications

Pregnancies affected by obesity are at high risk for developing metabolic complications with oxidative stress and adipocyte dysfunction contributing to the underlying pathologies. Few studies have examined the role of dietary interventions, especially those involving antioxidants including polyphenolic flavonoids found in fruits and vegetables on these pathologies in high-risk pregnant women. We conducted an 18 gestation-week randomized controlled trial to examine the effects of a dietary intervention comprising of whole blueberries and soluble fiber vs. control (standard prenatal care) on biomarkers of oxidative stress/antioxidant status and adipocyte and hormonal functions in pregnant women with obesity (n = 34). Serum samples …

Serum Urate And Cardiovascular Events In The Dcct/Edic Study, Alicia J. Jenkins, Barbara H. Braffett, Arpita Basu, Ionut Bebu, Samuel Dagogo-Jack, Trevor J. Orchard, Amisha Wallia, Maria F. Lopes-Virella, W. Timothy Garvey, John M. Lachin, Timothy J. Lyons

Kinesiology and Nutrition Sciences Faculty Publications

In type 2 diabetes, hyperuricemia is associated with cardiovascular disease (CVD) and the metabolic syndrome (MetS), but associations in type 1 diabetes (T1D) have not been well-defined. This study examined the relationships between serum urate (SU) concentrations, clinical and biochemical factors, and subsequent cardiovascular events in a well-characterized cohort of adults with T1D. In 973 participants with T1D in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study (DCCT/EDIC), associations were defined between SU, measured once in blood collected 1997-2000, and (a) concurrent MetS and (b) incident 'any CVD' and major adverse cardiovascular events (MACE) through 2013. …

Impact Of Nutrition-Based Interventions On Athletic Performance During Menstrual Cycle Phases: A Review, Macy M. Helm, Graham R. Mcginnis, Arpita Basu

Kinesiology and Nutrition Sciences Faculty Publications

Despite the steady increase in female participation in sport over the last two decades, comprehensive research on interventions attenuating the influence of female menstrual physiology on performance remains scarce. Studies involving eumenorrheic women often only test in one menstrual phase to limit sex hormone variance, which may restrict the application of these findings to the rest of the menstrual cycle. The impacts of nutrition-based interventions on athletic performance throughout the menstrual cycle have not been fully elucidated. We addressed this gap by conducting a focused critical review of clinical studies that reported athletic outcomes as well as menstrual status for …

Dietary Strawberries Improve Cardiometabolic Risks In Adults With Obesity And Elevated Serum Ldl Cholesterol In A Randomized Controlled Crossover Trial, Arpita Basu, Kenneth Izuora, Nancy M. Betts, Jefferson W. Kinney, Arnold M. Salazar, Jeffrey L. Ebersole, R. Hal Scofield

Kinesiology and Nutrition Sciences Faculty Publications

Background and aims: Dietary berries, such as strawberries, are rich in bioactive compounds and have been shown to lower cardiometabolic risk. We examined the effects of two dietary achievable doses of strawberries on glycemic control and lipid profiles in obese adults with elevated serum LDL cholesterol (LDL-C). Methods: In this 14-week randomized controlled crossover study, participants were assigned to one of the three arms for four weeks separated by a one-week washout period: control powder, one serving (low dose: 13 g strawberry powder/day), or two-and-a-half servings (high dose: 32 g strawberry powder/day). Participants were instructed to follow their usual diet …

Quantification And Verification Of Cardiorespiratory Fitness In Adults With Prehypertension, Dharini M. Bhammar, Lung-Chang Chien

Kinesiology and Nutrition Sciences Faculty Publications

Background: Low cardiorespiratory fitness is associated with increased risk of hypertension and atherosclerosis in adults with prehypertension. The purpose of this study was to quantify cardiorespiratory fitness and to examine the utility of supramaximal constant-load verification testing for validating maximal oxygen uptake (VO2max) attainment in adults with prehypertension. Methods: Eleven adults (four women) with prehypertension (22.5 +/- 2.9 y; body mass index (BMI): 24.6 +/- 3.2 kg center dot m(2)) underwent an incremental exercise test followed 15 min later by a verification test at 105% of maximal work rate on a cycle ergometer. Results: There was no statistical difference in …

Effects Of Resistance Training On Muscle Quality Index, Muscle Strength, Functional Capacity, And Serum Immunoglobulin Levels Between Obese And Non-Obese Older Women, Paulo Roberto Silva Junior, Dahan Da Cunha Nascimento, Ivo Vieira De Sousa Neto, Silvana Schwerz Funghetto, Ramires Alsamir Tibana, James W. Navalta, Fabiani Lage Rodrigues Beal, Jonato Prestes

Kinesiology and Nutrition Sciences Faculty Publications

International Journal of Exercise Science 14(7): 707-726, 2021. Considering the negative impact of obesity on neuromuscular and immune systems, we sought to compare the effects of a 10-week resistance training (RT) program on muscle quality index (MQI), muscle strength, functional capacity, and immunoglobulins in older women with and without obesity. Thirty-nine older women participated in the present study (age: 69.02 ± 6.16, fat (%): 38.80% ± 6.28) and underwent a linear RT program performed on two non-consecutive days of the week. Body composition, functional tests, immunoglobulins, muscle quality of upper and lower limbs and absolute muscular strength of the upper …

Validity And Reliability Of Physiological Data In Applied Settings Measured By Wearable Technology: A Rapid Systematic Review, Bryson Carrier, Brenna Barrios, Brayden D. Jolley, James W. Navalta

Kinesiology and Nutrition Sciences Faculty Publications

The purpose of this review was to evaluate the current state of the literature and to identify the types of study designs, wearable devices, statistical tests, and exercise modes used in validation and reliability studies conducted in applied settings/outdoor environments. This was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. We identified nine articles that fit our inclusion criteria, eight of which tested for validity and one tested for reliability. The studies tested 28 different devices with exercise modalities of running, walking, cycling, and hiking. While there were no universally common analytical techniques used …

Evaluation Of Repetitive Jumping Intensity On The Digi-Jump Machine, T. Scott Lyons, James W. Navalta, Whitley J. Stone, Scott W. Arnett, Mark A. Schafer, Laura Igaune

Kinesiology and Nutrition Sciences Faculty Publications

Cardiorespiratory endurance is an important element of aerobic fitness, particularly in weight management and reducing risk for cardiovascular disease. While there are numerous options for aerobic exercise, rope jumping is often overlooked. In addition to regular exercise and a healthy diet, the American Heart Association strongly recommends rope jumping. The first purpose of this study was to determine the steady state metabolic cost of repetitive jumping on the Digi-Jump machine to evaluate whether exercise on this device is more or less strenuous than similar exercise with a jump rope, as demonstrated in previous literature. A second purpose was to determine …

High Supervised Resistance Training In Elderly Women: The Role Of Supervision Ratio, Denis Cesar Leite Vieira, Dahan Da Cunha Nascimento, Vitor Tajra, Tatiane Gomes Teixeira, Darlan Lopes De Farias, Ramires Tibana, Alessandro Oliveira Silva, Thiago Santos Rosa, Milton Rocha Moraes, Fabrício Azevedo Voltarelli, James W. Navalta, Jonato Prestes

Kinesiology and Nutrition Sciences Faculty Publications

The objective of this study was to compare the effects of very high supervision (VHS-RT) versus high supervision (HS-RT) ratio resistance training (RT) on irisin, brain-derived neurotrophic factor (BNDF), muscle strength, functional capacity, and body composition in elderly women. Participants performed daily undulating periodized RT over 16 weeks with two different supervision ratios: VHS-RT at 1:2 (supervisor/subject) or HS-RT at 1:5. Serum was used to analyze brain derived neurotropic factor (BDNF) and irisin by enzyme-linked immunosorbent assay (ELISA). Body composition was evaluated by dual-energy X-ray absorptiometry, while functional capacity was evaluated using the Six-minute walk test, and Timed Up and …

In Vitro And In Vivo Effects Of Flavonoids On Peripheral Neuropathic Pain, Paramita Basu, Arpita Basu

Kinesiology and Nutrition Sciences Faculty Publications

Neuropathic pain is a common symptom and is associated with an impaired quality of life. It is caused by the lesion or disease of the somatosensory system. Neuropathic pain syndromes can be subdivided into two categories: central and peripheral neuropathic pain. The present review highlights the peripheral neuropathic models, including spared nerve injury, spinal nerve ligation, partial sciatic nerve injury, diabetes-induced neuropathy, chemotherapy-induced neuropathy, chronic constriction injury, and related conditions. The drugs which are currently used to attenuate peripheral neuropathy, such as antidepressants, anticonvulsants, baclofen, and clonidine, are associated with adverse side effects. These negative side effects necessitate the investigation …

New Author Guidelines In Statistical Reporting: Embracing An Era Beyond P < .05, Samantha Johnson, Whitley J. Stone, Jennifer Bunn, Scott Lyons, James W. Navalta

Kinesiology and Nutrition Sciences Faculty Publications

Statistical reporting of quantitative research data has been plagued by potential bias and reporting suppression due to a single numerical output: the p-value. While there is great importance in its merit, creating a pass-fail system (set at point of .05) has created a culture of researchers submitting their project’s data to a filing cabinet if it does not yield “statistical significance” based on this value. The editors of the International Journal of Exercise Science are following the American Statistical Association’s call for statistical reform by adjusting our reporting guidelines to the following requirements: [1.] make an intentional effort to move …

International Society Of Sports Nutrition Position Stand: Nutritional Considerations For Single-Stage Ultra-Marathon Training And Racing, Nicholas B. Tiller, Justin D. Roberts, Liam Beasley, Shaun Chapman, Jorge M. Pinto, Lee Smith, Melanie Wiffin, Mark Russel, S. Andy Sparks, Lauren Duckworth, John O'Hara, Louise Sutton, Jose Antonio, Darryn S. Willoughby, Michael D. Tarpey, Abbie E. Smith-Ryan, Michael J. Ormsbee, Todd A. Astorino, Richard B. Kreider, Graham R. Mcginnis, Jeffrey R, Stout, Johneric W. Smith, Shawn M. Arent, Bill I. Campbell, Laurent Bannock

Kinesiology and Nutrition Sciences Faculty Publications

In this Position Statement, the International Society of Sports Nutrition (ISSN) provides an objective and critical review of the literature pertinent to nutritional considerations for training and racing in single-stage ultra-marathon. Recommendations for Training. i) Ultra-marathon runners should aim to meet the caloric demands of training by following an individualized and periodized strategy, comprising a varied, food-first approach; ii) Athletes should plan and implement their nutrition strategy with sufficient time to permit adaptations that enhance fat oxidative capacity; iii) The evidence overwhelmingly supports the inclusion of a moderate-to-high carbohydrate diet (i.e., ~ 60% of energy intake, 5–8 g·kg− 1·d− 1) …

Dietary Fiber Intake And Glycemic Control: Coronary Artery Calcification In Type 1 Diabetes (Cacti) Study, Arpita Basu, Amy C. Alman, Janet K. Snell-Bergeon

Kinesiology and Nutrition Sciences Faculty Publications

Background: Dietary fiber has been recommended for glucose control, and typically low intakes are observed in the general population. The role of fiber in glycemic control in reported literature is inconsistent and few reports are available in populations with type 1 diabetes (T1D). Methods: Using data from the Coronary Artery Calcification in Type 1 Diabetes (CACTI) study [n = 1257; T1D: n = 568; non-diabetic controls: n = 689] collected between March 2000 and April 2002, we examined cross-sectional (baseline) and longitudinal (six-year follow-up in 2006–2008) associations of dietary fiber and HbA1c. Participants completed a validated food frequency questionnaire, and …

Differential Tissue Response To Growth Hormone In Mice, Ryan Berry, Graham R. Mcginnis, Ronadip R. Banerjee, Martin E. Young, Stuart J. Frank

Kinesiology and Nutrition Sciences Faculty Publications

Growth hormone (GH) has been shown to act directly on multiple tissues throughout the body. Historically, it was believed that GH acted directly in the liver and only indirectly in other tissues via insulin‐like growth hormone 1 (IGF‐1). Despite extensive work to describe GH action in individual tissues, a comparative analysis of acute GH signaling in key metabolic tissues has not been performed. Herein, we address this knowledge gap. Acute tissue response to human recombinant GH was assessed in mice by measuring signaling via phospho‐STAT5 immunoblotting. STAT5 activation is an easily and reliably detected early marker of GH receptor engagement. …

Running Economy While Running In Extreme Cushioning And Normal Cushioning Running Shoes, Miles A. Mercer, Tori M. Stone, John C. Young, John Mercer

Kinesiology and Nutrition Sciences Faculty Publications

The purpose of the study was to determine if running economy was influenced by wearing maximal cushioning shoes vs. control (neutral cushioning) shoes. (Please see Abstract in text)

Physiological And Pharmacokinetic Effects Of Oral 1,3-Dimethylamylamine Administration In Men, Brian Schilling, Kelley Hammond, Richard Bloomer, Chaela Presley, Charles Yates

Kinesiology and Nutrition Sciences Faculty Publications

No abstract provided.

Impact Of A Dietary Supplement Containing 1,3-Dimethylamylamine On Blood Pressure And Bloodborne Markers Of Health: A 10-Week Intervention Study, Paul Whitehead, Brian Schilling, Tyler Farney, Richard Bloomer

Kinesiology and Nutrition Sciences Faculty Publications

No abstract provided.

Comparison Of Pre Workout Nitric Oxide Stimulating Dietary Supplements On Skeletal Muscle Oxygen Saturation, Blood Nitrate/Nitrite, Lipid Peroxidation, And Upper Body Exercise Performance In Resistance Trained Men, Richard Bloomer, Tyler Farney, John Trepanowski, Cameron Mccarthy, Robert Canale, Brian Schilling

Kinesiology and Nutrition Sciences Faculty Publications

No abstract provided.

Effects Of Moderate Volume, High Load Lower Body Resistance Training On Strength And Function In Persons With Parkinson’S Disease: A Pilot Study, Brian Schilling, Ronald Pfeiffer, Mark Ledoux, Robyn Karlage, Richard Bloomer, Michael Falvo

Kinesiology and Nutrition Sciences Faculty Publications

No abstract provided.

Effect Of Eicosapentaenoic And Docosahexaenoic Acid On Resting And Exercise Induced Inflammatory And Oxidative Stress Biomarkers: A Randomized, Placebo Controlled, Cross­Over Study, Richard Bloomer, Douglas Larson, Kelsey Fisher-Wellman, Andrew Galpin, Brian Schilling

Kinesiology and Nutrition Sciences Faculty Publications

No abstract provided.

Effect Of The Dietary Supplement Meltdown On Catecholamine Secretion, Markers Of Lipolysis, And Metabolic Rate In Men And Women: A Randomized, Placebo Controlled, Cross­Over Study, Richard Bloomer, Robert Canale, Megan Blankenship, Kelley Hammond, Kelsey Fisher-Wellman, Brian Schilling

Kinesiology and Nutrition Sciences Faculty Publications

No abstract provided.

Dietary Supplement Increases Plasma Norepinephrine, Lipolysis, And Metabolic Rate In Resistance Trained Men, Richard Bloomer, Kelley Fisher-Wellman, Kelley Hammond, Brian Schilling, Adrianna Weber, Bradford Cole

Kinesiology and Nutrition Sciences Faculty Publications

Correction to Richard J Bloomer, Kelsey H Fisher-Wellman, Kelley G Hammond, Brian K Schilling, Adrianna A Weber and Bradford J Cole: Dietary supplement increases plasma norepinephrine, lipolysis, and metabolic rate in resistance trained men. Journal of the International Society of Sports Nutrition 2009, 6: 4

Dietary Supplement Increases Plasma Norepinephrine, Lipolysis, And Metabolic Rate In Resistance Trained Men, Richard Bloomer, Kelley Fisher-Wellman, Kelley Hammond, Brian K. Schilling, Adrianna Weber, Bradford Cole

Kinesiology and Nutrition Sciences Faculty Publications

Background

Dietary supplements targeting fat loss and increased thermogenesis are prevalent within the sport nutrition/weight loss market. While some isolated ingredients have been reported to be efficacious when used at high dosages, in particular in animal models and/or via intravenous delivery, little objective evidence is available pertaining to the efficacy of a finished product taken by human subjects in oral form. Moreover, many ingredients function as stimulants, leading to increased hemodynamic responses. The purpose of this investigation was to determine the effects of a finished dietary supplement on plasma catecholamine concentration, markers of lipolysis, metabolic rate, and hemodynamics.

Methods

Ten …

Prior Exercise And Antioxidant Supplementation: Effect On Oxidative Stress And Muscle Injury, Richard Bloomer, Michael Falvo, Brian Schilling, Webb Smith

Kinesiology and Nutrition Sciences Faculty Publications

No abstract provided.