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University of Nebraska Medical Center

Theses & Dissertations

Theses/Dissertations

2016

Alcohol

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Aldehyde Adducts And Lung Injury, Muna Sapkota Aug 2016

Aldehyde Adducts And Lung Injury, Muna Sapkota

Theses & Dissertations

From the time of discovery, people have used both alcohol and tobacco in various forms all around the world. Alcohol abuse and cigarette smoking causes thousands of preventable deaths in the US each year. Several lung diseases such as COPD, asthma, respiratory infections, pneumonia, acute respiratory distress syndrome, cancer of neck, throat, mouth and lung are associated with smoking and drinking. Even though some studies have examined the role of alcohol and cigarette smoke in lung diseases, only a few studies have focused on the role of reactive aldehydes generated in the lungs of those who abuse alcohol and smoke …