Medicine and Health Sciences Commons^™

Fgdb: Database Of Follicle Stimulating Hormone Glycans, Sushil Kumar Shakyawar, Sanjit Pandey, David J. Harvey, George Bousfield, Chittibabu Guda

Journal Articles: Genetics, Cell Biology & Anatomy

Glycomics, the study of the entire complement of sugars of an organism has received significant attention in the recent past due to the advances made in high throughput mass spectrometry technologies. These analytical advancements have facilitated the characterization of glycans associated with the follicle-stimulating hormones (FSH), which play a central role in the human reproductive system both in males and females utilizing regulating gonadal (testicular and ovarian) functions. The irregularities in FSH activity are also directly linked with osteoporosis. The glycoanalytical studies have been tremendously helpful in understanding the biological roles of FSH. Subsequently, the increasing number of characterized FSH …