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University of Nebraska - Lincoln

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Immunology and Infectious Disease

School of Biological Sciences: Dissertations, Theses, and Student Research

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Full-Text Articles in Medicine and Health Sciences

Placental Hpv Infection In Hiv Positive And Hiv Negative Zambian Women, Chrispin Chisanga Apr 2014

Placental Hpv Infection In Hiv Positive And Hiv Negative Zambian Women, Chrispin Chisanga

School of Biological Sciences: Dissertations, Theses, and Student Research

Human papillomaviruses (HPVs) have been reported to infect epithelial trophoblastic cells of the placenta, induce cell death and even cause placental malfunction associated with spontaneous preterm delivery. To date, no study has been conducted to determine the role of HIV on HPV genotype distribution and pathogenesis in the placental compartment. This is despite the evidence that the human immunodeficiency virus (HIV) can decrease the cellular immune response and increase the incidence of malignant cancers in HPV patients. Therefore, in this study, we analyzed 200 genomic DNA (gDNA) samples extracted from paraffin embedded placental tissues of HIV positive and HIV negative …


Some Monogenetic Trematodes From The Galapagos Islands And The Neighboring Pacific, Frank Grose Meserve Aug 1935

Some Monogenetic Trematodes From The Galapagos Islands And The Neighboring Pacific, Frank Grose Meserve

School of Biological Sciences: Dissertations, Theses, and Student Research

Introduction

Trematodes are parasitic, unsegmented, flattened (rarely cylindrical) worms. They have ventral, anterior, posterior or median attachment organs. The sense organs are poorly developed. The mouth is terminal or ventral and subterminal. The intestine is usually forked with or without lateral branches. The animals, with few exceptions, are hermaphroditic. The ovary is usually single. They have one, two, or more testes. The development is direct with only one host in the ectoparasitic Monogenea and indirect in the Digenea which have two or more hosts. The digenetic trematodes usually parasitize vertebrates which serve as their primary hosts and invertebrates (Mollusca) which …