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Full-Text Articles in Medicine and Health Sciences
Pesticide Exposures And Other Agricultural Risk Factors For Leukemia Among Men In Iowa And Minnesota, Linda Morris Brown, Aaron Blair, Robert Gibson, George D. Everett, Kenneth P. Cantor, Leonard M. Schuman, Leon F. Burmeister, Stephanie F. Van Lier, Fred Dick
Pesticide Exposures And Other Agricultural Risk Factors For Leukemia Among Men In Iowa And Minnesota, Linda Morris Brown, Aaron Blair, Robert Gibson, George D. Everett, Kenneth P. Cantor, Leonard M. Schuman, Leon F. Burmeister, Stephanie F. Van Lier, Fred Dick
Public Health Resources
Mortality surveys and death certificate studies have suggested an association between leukemia and farming. To investigate whether exposure to carcinogens in an agricultural setting is related to risk of leukemia, the authors conducted a population-based case-control inter view study of 578 white men with leukemia and 1245 controls living in Iowa and Minnesota. Consistent with recent mortality studies, there were slight, but significant, elevations in risk for all leukemia (odds ratio (OR) 1.2) and chronic lymphocytic leukemia (OR 1.4) for farmers compared to nonfarmers. There were no significant associations with leukemia for exposure to specific fungicides, herbicides (including 2.4-1) and …
Detection Of Shigella In Feces Using Dna Amplification, Gad Frankel, Lee Riley, Jorge A. Giron, Janice Valmassoi, Adam Friedmann, Nancy Strockbine, Stanley Falkow, Gary K. Schoolnik
Detection Of Shigella In Feces Using Dna Amplification, Gad Frankel, Lee Riley, Jorge A. Giron, Janice Valmassoi, Adam Friedmann, Nancy Strockbine, Stanley Falkow, Gary K. Schoolnik
Public Health Resources
A rapid diagnostic method employing a polymerase chain reaction procedure (PCR) was used to identify Shigella and enteroinvasive Escherichia Coli. This procedure amplified a region of the invasive-associated locus (ial) from a crude DNA extract of feces. A synthetic 21-base oligonucleotide corresponding to the ial gene sequence was shown to specifically hybridize only with enteroinvasive E. Coli (EIEC) strains and Shigella species. Upon PCR amplification, a 320-base pair fragment was generated in DNA extracted from feces reconstituted with EIEC or Shigella flexneri but not in DNA from 70 normal stools lacking these organisms and could be readily …