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Full-Text Articles in Medicine and Health Sciences

Risk Factors For Persistent Mrsa Colonization In Children With Multiple Intensive Care Unit Admissions, Victor Popoola, Pranita Tamma, Nicholas Reich, Trish Perl, Aaron Milstone Jul 2013

Risk Factors For Persistent Mrsa Colonization In Children With Multiple Intensive Care Unit Admissions, Victor Popoola, Pranita Tamma, Nicholas Reich, Trish Perl, Aaron Milstone

Nicholas G Reich

We studied methicillin-resistant Staphylococcus aureus (MRSA)-colonized children with multiple intensive care unit (ICU) admissions to assess the persistence of MRSA colonization. Our data found that children with more than 1 year between ICU admissions had a higher prevalence of MRSA colonization than the overall ICU population, which supports empirical contact precautions for children with previous MRSA colonization.


Addressing Economic Devastation And Built Environment Degradation To Prevent Violence: A Photovoice Project Of Detroit Youth Passages, Louis Graham, Armando Reyes, William Lopez, Alana Gracey, Rachel Snow, Mark Padilla Jan 2013

Addressing Economic Devastation And Built Environment Degradation To Prevent Violence: A Photovoice Project Of Detroit Youth Passages, Louis Graham, Armando Reyes, William Lopez, Alana Gracey, Rachel Snow, Mark Padilla

Louis Graham

This project increased awareness about issues of violence to youth, their communities, and policy makers through the technique of photovoice and its translation into photo exhibitions and other community events. Youth participants learned photography skills, engaged in critical communal discussions about important issues affecting their health, wrote reflective stories about their photos, and engaged in policy change efforts. Their photos depict the need to address economic devastation and built environment degradation to prevent violence in their communities. Youth presented policy makers and community leaders with an “insider’s perspective” of the issues facing their communities, with the hope of promoting policy …


Better Learning In Schools To Improve Attitudes Toward Abstinence And Intentions For Safer Sex Among Adolescents In Urban Nepal, Rachana Manandhar Shrestha, Keiko Otsuka, Krishna C. Poudel, Junko Yasuoka, Medin Lamichhane, Masamine Jimba Jan 2013

Better Learning In Schools To Improve Attitudes Toward Abstinence And Intentions For Safer Sex Among Adolescents In Urban Nepal, Rachana Manandhar Shrestha, Keiko Otsuka, Krishna C. Poudel, Junko Yasuoka, Medin Lamichhane, Masamine Jimba

Krishna C. Poudel

Background: School-based sex education is an effective medium to convey health information and skills about preventing sexually transmitted infections (STIs) and unwanted pregnancies among adolescents. However, research on school-based sex education is limited in many developing countries, including Nepal. This study thus had two main objectives: (1) to assess students’ evaluation of school-based sex education, and (2) to examine the associations between students’ evaluations of school-based sex education and their (a) attitudes toward abstinence and (b) intentions for safer sex. Methods: This cross-sectional study was conducted among 634 students from six schools in the Kathmandu Valley during May–June 2010. We …


Interactions Between Serotypes Of Dengue Highlight Epidemiological Impact Of Cross-Immunity, Nicholas Reich, Sourya Shrestha, Aaron King, Pejman Rohani, Justin Lessler, Siripen Kalayanarooj, In-Kyu Yoon, Robert Gibbons, Donald Burke, Derek Cummings Jan 2013

Interactions Between Serotypes Of Dengue Highlight Epidemiological Impact Of Cross-Immunity, Nicholas Reich, Sourya Shrestha, Aaron King, Pejman Rohani, Justin Lessler, Siripen Kalayanarooj, In-Kyu Yoon, Robert Gibbons, Donald Burke, Derek Cummings

Nicholas G Reich

Dengue, a mosquito-borne virus of humans, infects over 50 million people annually. Infection with any of the four dengue serotypes induces protective immunity to that serotype, but does not confer long-term protection against infection by other serotypes. The immunological interactions between sero- types are of central importance in understanding epidemiological dynamics and anticipating the impact of dengue vaccines. We analysed a 38-year time series with 12 197 serotyped dengue infections from a hospital in Bangkok, Thailand. Using novel mechanistic models to represent different hypothesized immune interactions between serotypes, we found strong evidence that infec- tion with dengue provides substantial short-term …


Improved Quality Of Life After Surgery For Pelvic Organ Prolapse In Nepalese Women, Rolina Dhital, Keiko Otsuka, Krishna C. Poudel, Junko Yasuoka, Ganesh Dangal, Masamine Jimba Jan 2013

Improved Quality Of Life After Surgery For Pelvic Organ Prolapse In Nepalese Women, Rolina Dhital, Keiko Otsuka, Krishna C. Poudel, Junko Yasuoka, Ganesh Dangal, Masamine Jimba

Krishna C. Poudel

Background: Pelvic organ prolapse (POP) is a common gynecological condition that can affect quality of life (QOL) in women. In Nepal, the prevalence of POP is high, but many affected women are still deprived of treatment. Vaginal hysterectomy with pelvic floor repair is one of the common treatment options for advanced POP. However, QOL outcomes after surgery have not been reported in low-income countries. Thus, we aimed to examine changes in QOL among Nepalese women with POP after such surgery. Methods: This longitudinal study was conducted in the selected central and peripheral hospitals in Nepal where vaginal hysterectomy was being …


Serum 25-Hydroxyvitamin D Levels And C-Reactive Protein In Persons With Human Immunodeficiency Virus Infection, Kalpana Poudel-Tandukar, Krishna C. Poudel, Masamine Jimba, Jun Kobayashi, C. Anderson Johnson, Paula H. Palmer Jan 2013

Serum 25-Hydroxyvitamin D Levels And C-Reactive Protein In Persons With Human Immunodeficiency Virus Infection, Kalpana Poudel-Tandukar, Krishna C. Poudel, Masamine Jimba, Jun Kobayashi, C. Anderson Johnson, Paula H. Palmer

Krishna C. Poudel

Human immunodeficiency virus (HIV) infection has frequently been associated with vitamin D deficiency as well as chronic inflammatory response. We tested the hypothesis of an independent relationship between serum concentrations of 25-hydroxyvitamin D [25(OH)D] and high-sensitivity C-reactive protein (CRP) in a cohort of HIV-positive people. A cross-sectional survey was conducted among 316 HIV-positive people (181 men and 135 women) aged 16 to 60 years residing in the Kathmandu Valley, Nepal. Serum high-sensitivity CRP concentrations and serum 25(OH)D levels were measured by the latex agglutination nephelometry method and the competitive protein-binding assay, respectively. The relationship between serum CRP concentrations and 25(OH)D …