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Full-Text Articles in Medicine and Health Sciences
Treg Regulation In Periodontal Disease During Pregnancy., Aislinn Leah Hays
Treg Regulation In Periodontal Disease During Pregnancy., Aislinn Leah Hays
Electronic Theses and Dissertations
Background: Although pregnancy is prone to induce more severe periodontal inflammation and tissue damage, its mechanism remains elusive. Periodontal diseases during pregnancy are associated with adverse pregnancy outcomes including preterm birth or low birth weight. Animal models are ideal for investigating immunological mechanisms in periodontal disease. With a newly modified ligature-induced disease model, we managed to develop periodontal disease in pregnant mice and investigate the immunological mechanism of more severe symptoms during pregnancy. Hypothesis: We hypothesis that P. gingivalis infection during pregnancy will lead to a down-regulation of Treg cells, therefore causing increased inflammation and disease severity. Methods: A ligature-induced …
Cross-Cultural Investigation Of Birth Experience : A Comparison Between Mexico And The United States., Alice J Darling
Cross-Cultural Investigation Of Birth Experience : A Comparison Between Mexico And The United States., Alice J Darling
College of Arts & Sciences Senior Honors Theses
This study investigates the maternal birth experience through a cross-cultural lens. While the field of medical anthropology has researched birth practices of many cultures, few cross-cultural studies have been performed and no recent studies have suggested a transition in birthing. Ethnographic interviews with women and practitioners in Yucatán, Mexico and with women in Kentucky, United States allowed for a better understanding of the respective birthing environments. Grounded theory was then employed to develop a birth transition theory explaining changes occurring when society transitions from traditional birth practitioners to allopathic birth practitioners. The themes of knowledge, expectation and power were isolated …