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University of Louisville

The Cardinal Edge

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Articles 1 - 13 of 13

Full-Text Articles in Medicine and Health Sciences

The Social Determinants Of Health And Reentry: An Exploratory Study, Makayla Lewis, Brian Schaefer, Heather Ouellette Sep 2023

The Social Determinants Of Health And Reentry: An Exploratory Study, Makayla Lewis, Brian Schaefer, Heather Ouellette

The Cardinal Edge

Being released from jail affects a person’s ability to secure basic needs such as health, housing, and employment. Compounding these barriers are issues related to returning to impoverished communities, complicated relationships with families and support systems, and minimal reentry opportunities within jails and upon release. This study explores how the Opportunity Network’s reentry workbook is working to address the social determinants of health and improve perceptions of successful reentry outcomes.


Hyaluronan Modulated Expression Of Mmps 2, 9, And 12 In Macrophages, Jeffrey S. Miller, Caitlin Howard, Steven P. Jones Phd Sep 2023

Hyaluronan Modulated Expression Of Mmps 2, 9, And 12 In Macrophages, Jeffrey S. Miller, Caitlin Howard, Steven P. Jones Phd

The Cardinal Edge

Hyaluronan (HA) is a ubiquitously expressed Glycosaminoglycan (GAG) found as a main component of the extracellular matrix (ECM). Matrix metalloproteases (MMPs) are class of enzyme responsible for the degradation of multiple ECM components, including HA. Following a myocardial infarction (MI), ECM remodeling occurs in the infarct tissue and involves an accumulation of HA. Remodeling is facilitated by multiple cell types, including macrophages. During post-MI ECM remodeling, macrophages degrade and ingulf dead cells and ECM components, a process which requires the expression of MMPs. MMPs 2, 9, and 12 are known to be elevated post-MI; MMPs 9 and 12 are known …


A Logistics Approach To Improve Medication Reconciliation In The Outpatient Clinic Setting, Aysha Khan, Demetra Antimisiaris, Madison Perkins, Luz Fernandez Sep 2023

A Logistics Approach To Improve Medication Reconciliation In The Outpatient Clinic Setting, Aysha Khan, Demetra Antimisiaris, Madison Perkins, Luz Fernandez

The Cardinal Edge

Medication reconciliation (MR) is the process of determining the most accurate account of medication the patient is taking. Although MR seems simple, research has shown that 25% of medical errors are related to lack of medication reconciliation [1]. In the community clinic setting, the task of medication reconciliation falls on the Medical Assistants (MAs). A preliminary study of MR accuracy in an outpatient clinic found an average of 5.8 discrepancies in the chart medication list [2]. The most notable were incomplete directions, wrong directions, or wrong frequency of dosing. Unoptimized medication use is estimated to result in 275,869 deaths per …


All-Cause And Opioid-Related Mortality Compared Between Traumatic Spinal Cord Injury And The Us General Population, Jaden Whitehead, Beatrice Ugiliweneza Sep 2023

All-Cause And Opioid-Related Mortality Compared Between Traumatic Spinal Cord Injury And The Us General Population, Jaden Whitehead, Beatrice Ugiliweneza

The Cardinal Edge

Individuals with spinal cord injury (SCI) are susceptible to the misuse of opioids due to the introduction of these substances for pain management. There are very few studies examining the relationship between unintentional deaths caused by opioid usage following spinal cord injury. The objective of this study was to evaluate the trend of opioid-related mortality of individuals with spinal cord injury (SCI) over the years and compare these findings to the mortality rates due to opioid misuse in the general population. In this study, we used data provided by the National Spinal Cord Injury Model Systems (NSCIMS) for SCI 1999-2016 …


Self Determination Theory And Health Behavior Interventions, Anna T. Simpson Sep 2023

Self Determination Theory And Health Behavior Interventions, Anna T. Simpson

The Cardinal Edge

Physical and mental health contribute to a person’s overall sense of well-being. People generally want to live happy and healthy lives, so they make decisions that will increase their well-being. Many factors contribute to our health, but health behavior is something we can modify. Health behavior interventions aim to promote healthy choices and a sense of well-being in patients. Interventions have a theoretical basis that influences the design of the intervention. Public health interventions have used self-determination theory (SDT) and its components to guide interventions that promote health behavior change in various populations. This paper will seek to understand the …


From Awareness To Action: Understanding And Addressing Health Disparities, Aamira Shah Sep 2023

From Awareness To Action: Understanding And Addressing Health Disparities, Aamira Shah

The Cardinal Edge

In the United States, marginalized groups consistently face barriers to healthcare services necessary for maintaining quality of life and achieving positive health outcomes. Health disparities can be defined as “preventable differences in the burden of disease, injury, violence, or opportunities to achieve optimal health that are experienced by populations that have been disadvantaged by their social or economic status, geographic location, or environment” (CDC, 2008). With input from insightful interviews, this article seeks to investigate specific challenges faced by marginalized groups in the healthcare setting and provide potential solutions to reduce health disparities.


An Evaluation Of Covid-19 Vaccination Rates Of The Patients At The Kentucky Racing Health Services Center, Aditya Mehta, Dedra Hayden Sep 2022

An Evaluation Of Covid-19 Vaccination Rates Of The Patients At The Kentucky Racing Health Services Center, Aditya Mehta, Dedra Hayden

The Cardinal Edge

COVID-19 vaccines have been widely available to the U.S. public since early 2021. However, vaccination rates still vary considerably across geographical areas and different populations. The objective of this study was to research overall vaccination rates against COVID-19 for Latinx patients at the Kentucky Racing Health Services Center (KRHSC). Vaccination and booster data was collected from June to December 2021 for all unique patients visiting the center. It was initially hypothesized that these rates of vaccination and booster doses for the KRHSC patients would be lower than the data reported by Kentucky and Jefferson County. After a retrospective review, the …


Evaluation Of Respiratory Function Using Blood Gas Parameters In Yucatan Minipigs Following Spinal Cord Injury, Jackson Gallagher, Monique Morgan, Chase Knibbe, Destiny Gibson, Maxwell Boakye Sep 2022

Evaluation Of Respiratory Function Using Blood Gas Parameters In Yucatan Minipigs Following Spinal Cord Injury, Jackson Gallagher, Monique Morgan, Chase Knibbe, Destiny Gibson, Maxwell Boakye

The Cardinal Edge

There are approximately 17,810 new spinal cord injuries (SCI) in the U.S. each year [1]. Physical damage to the spinal cord has the potential to interfere with normal motor, sensory, and/or autonomic function, such as impairment of the respiratory system. In fact, respiratory insufficiency is the number one cause of mortality and morbidity after SCI. The more rostral the injury, the more likely there will be disruption to normal ventilation (generally rostral to T6) [2]. To conduct relevant preclinical research, it has been shown that large animal models, such as the Yucatan minipig, have a better success rate of translating …


A Literature Review On The Development Of Upper Limbs In Humans, Anh T. Phan Sep 2021

A Literature Review On The Development Of Upper Limbs In Humans, Anh T. Phan

The Cardinal Edge

The development of tetrapod upper limbs shares an evolutionary origin and has been adapted and specialized for different functions for different species, such as flight in birds, swimming and balance in sea mammals, and coordination and grabbing objects in humans. The basis of tetrapod limb development has common developmental patterns, starting with the formation of the limb bud via Sonic hedgehog (Shh) signaling, where later developmental steps are modified for specialized functions. This review covers the basic developmental patterns of mammalian tetrapod development seen in humans, beginning with the formation of the limb bud, to the axis development of the …


Angiogenesis' Effect Overall On Health And Disease, Wendy Tang Sep 2021

Angiogenesis' Effect Overall On Health And Disease, Wendy Tang

The Cardinal Edge

Angiogenesis plays a major role in the development of diseases and cancer. The development of illnesses like metastatic breast cancer, cell carcinomas, tumors and various other illnesses, originate from the activation of endothelial cells. When the vascular endothelial growth factor (VEGF) is released from hypoxic tissues, they bind to vascular endothelial growth factor receptors (VEGFR). The binding of VEGF and VEGFR allows for cellular proliferation, increased migration of lattice networks, and the invasion of endothelial cells, which stimulate the formation of new blood vessels from pre-existing ones. As a result, it can be concluded that the inhibition of VEGFs would …


Microbial Influence On Alzheimer's Disease, Ashley N. Hamby Sep 2021

Microbial Influence On Alzheimer's Disease, Ashley N. Hamby

The Cardinal Edge

No abstract provided.


Sexual Health Misinformation And Potential Interventions Among Youth On Social Media, Jahnavi Sunkara Sep 2021

Sexual Health Misinformation And Potential Interventions Among Youth On Social Media, Jahnavi Sunkara

The Cardinal Edge

With the rise of the internet and social media, many adolescents and young adults have turned to the internet and social media for sexual health information. However, this can be problematic because sexual health misinformation on social media utilizes a variety of techniques to quickly disseminate and retain that misinformation in users. Historically, the spread of sexual health misinformation has specifically negatively impacted adolescents and young adults regarding two sexual health topics: contraceptives and HPV vaccination. Current evidence demonstrates that a combination of corrections and inoculation would be effective against general health misinformation. However, there is a lack of research …


Comparing Medical Student Nonverbal Behavior With Cisgender And Transgender Standardized Patients, Meghan M. Schneider, Emily J. Noonan, Laura Weingartner Sep 2021

Comparing Medical Student Nonverbal Behavior With Cisgender And Transgender Standardized Patients, Meghan M. Schneider, Emily J. Noonan, Laura Weingartner

The Cardinal Edge

It is essential for medical students to effectively communicate with patients of all gender identities. Evaluating nonverbal behavior is one way to assess the quality of patient care – examining providers’ behaviors while working with cisgender and transgender patients can identify potential biases linked to patient identity. To evaluate nonverbal behavior, the authors analyzed video-recorded training sessions with medical students interviewing standardized patients who identified as cisgender or transgender women. All students identified as cisgender men or cisgender women. The authors rated ten nonverbal behaviors from 1-7 and noted whether these behaviors were perceived to detract from the encounter. Average …