Medicine and Health Sciences Commons^™

A Music-Therapy Robotic Platform For Children With Autism: A Pilot Study, Huanghao Feng, Mohammad H. Mahoor, Francesca Dino

Electrical and Computer Engineering: Faculty Scholarship

Children with Autism Spectrum Disorder (ASD) experience deficits in verbal and nonverbal communication skills including motor control, turn-taking, and emotion recognition. Innovative technology, such as socially assistive robots, has shown to be a viable method for Autism therapy. This paper presents a novel robot-based music-therapy platform for modeling and improving the social responses and behaviors of children with ASD. Our autonomous social interactive system consists of three modules. Module one provides an autonomous initiative positioning system for the robot, NAO, to properly localize and play the instrument (Xylophone) using the robot’s arms. Module two allows NAO to play customized songs …

Mechanisms Of Sensory Adaptation In The Primate Visual System, Boris Isaac Peñaloza Rojas

Electronic Theses and Dissertations

Under ecological conditions, the luminance impinging on the retina varies within a dynamic range of 220 dB. Stimulus contrast can also vary drastically within a scene, and eye movements leave little time for sampling luminance. In addition, the amount of information reaching our visual system far exceeds the brain’s information processing capacity. Given the limited dynamic range of its neurons and its limited capacity in processing visual information in real-time, the brain deploys both structural and functional solutions that work in tandem to adapt to the surroundings. In this work, employing visual psychophysics and computational neuroscience, we study the mechanisms …

Studying Facial Expression Recognition And Imitation Ability Of Children With Autism Spectrum Disorder In Interaction With A Social Robot, Farzaneh Askari

Electronic Theses and Dissertations

Children with Autism Spectrum Disorder (ASD) experience limited abilities in recognizing non-verbal elements of social interactions such as facial expressions [1]. They also show deficiencies in imitating facial expressions in social situations. In this Master thesis, we focus on studying the ability of children with ASD in recognizing facial expressions and imitating the expressions using a rear-projected expressive humanoid robot, called Ryan. Recent studies show that social robots such as Ryan have great potential for autism therapy. We designed and developed three studies, first to evaluate the ability of children with ASD in recognizing facial expressions that are presented to …

Patient-Specific Quantification Of The Relationship Between The Left Atrium Pressure And The Ostial Diameter Of The Left Atrial Appendage, Sky Tianqi Gao

Electronic Theses and Dissertations

The left atrial appendage has been a historically understudied region of the heart until fairly recently with the new understanding of its role in the stroke pathway of patients with atrial fibrillation. The goal of this study is to take a look at the biomechanical behavior of the left atrium and left atrial appendage under normal physiological loading conditions using material properties taken from biaxial stretch tests. Several different options for material properties models were tested and biaxial stretch test data of cadaveric human tissue samples for the left atrium and appendage were fit to a Fung-type strain-energy function for …

Modeling Hrtf For Sound Localization In Normal Listeners And Bilateral Cochlear Implant Users, Douglas A. Miller

Electronic Theses and Dissertations

Mathematical models can be very useful for understanding complicated systems and for testing algorithms through simulation that would be difficult or expensive to implement. This dissertation presents a model that attempts to simulate the sound localization performance of persons using bilateral cochlear implants. The expectation is that this model could prove to be a useful tool in developing new signal processing algorithms for neural encoding strategies.

The head related transfer function (HRTF) is a critical component of this model, and in the ideal case, provides the base characteristics of head shadow, torso and pinna effects. This defines the temporal, intensity …

Protein Aggregation Through Acoustic Cavitation, John A. Giarratano

Electronic Theses and Dissertations

Therapeutic proteins represent an essential piece of a health management plan for diseases such as diabetes, cancer, hemophilia, Crohn's Disease, and myocardial infarction. These proteins, however, must be maintained in their correct, biologically active conformation throughout processing, transportation, and delivery. This requirement poses serious engineering challenges because of a protein's susceptibility to thermodynamic instabilities resulting from the weak bonds driving the tertiary structure of the molecule. A particularly problematic type of protein degradation is aggregation. Administration of aggregated proteins, a particularly problematic degradation form, can have dire consequences, including blocking a patient's responsiveness to therapy, inducing immunogenicity, and even anaphylactic …

A Model For Electrical Communication Between Cochlear Implants And The Brain, Douglas A. Miller

Electronic Theses and Dissertations

In the last thirty years, cochlear implants have become an invaluable instrument in the treatment of severe-to-profound hearing impairment. An important aspect of research in the continued development of cochlear implants is the in vivo assessment of signal processing algorithms intended to improve perception of speech and other auditory signals. In trying to determine how closely cochlear implant recipients process sound relative to the processing done by a normal auditory system, various assessment techniques have been applied. The most common technique has been measurement of auditory evoked potentials (AEPs), which involves the recording of neural responses to auditory stimulation. Depending …

Image Processing Of Oct Glaucoma Images And Information Theory Analysis, Shuting Wang

Electronic Theses and Dissertations

Glaucoma is a group of optic nerve disease with progressive structural changes leading to loss of visual function. A careful examination and detection of changes in the optic nerve is the key to early diagnosis of glaucoma. Optical Coherence Tomography (OCT) is one of the known techniques of diagnosis of glaucoma. The patients' eyes are scanned and sub-surface images are captured from optical nerves. Captured OCT images usually suffer from noise and therefore image enhancement techniques can help doctors in better analysis of OCT images and diagnosis of glaucoma. In this thesis, we propose three successful algorithms for enhancing the …