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Admixture Mapping Of Subclinical And Clinical Cardiovascular Disease Among African Americans, Aditi Shendre
Admixture Mapping Of Subclinical And Clinical Cardiovascular Disease Among African Americans, Aditi Shendre
All ETDs from UAB
The purpose of this dissertation is to evaluate the association of local European ancestry (LEA) with subclinical and clinical cardiovascular (CV) disease (CVD) among African Americans in three prospective cohorts from the United States. CVD burden is higher among African Americans compared to other racial/ethnic groups and prevention efforts have led to the evaluation of subclinical measures of CVD such as carotid artery intima-media thickness (CIMT), and risk factors including the underlying genetic component of the disease. Admixed populations such as African Americans may have increased risk of disease as a result of the increased prevalence of a disease among …
Serum Vitamin D And C-Reactive Protein: Predictors Of Glucose Control In African-Americans With Type 2 Diabetes?, Mary Luree Garvin-Surpris
Serum Vitamin D And C-Reactive Protein: Predictors Of Glucose Control In African-Americans With Type 2 Diabetes?, Mary Luree Garvin-Surpris
All ETDs from UAB
Introduction African-Americans experience more years of life lost as a result of complications from type 2 diabetes mellitus (T2DM) than any other racial or ethnic group. Evidence suggests that serum 25(OH)D (serum vitamin D), generally low in African-Americans, may play a role in glucose control. In addition, elevated levels of chronic low-grade inflammation, measured by C-reactive protein (CRP), may also relate to glucose control. The purposes of this study were to determine whether serum 25(OH)D and CRP are independent predictors of glucose control in adult African-Americans with T2DM, after controlling for other factors associated with glucose control, and to examine …