Medicine and Health Sciences Commons^™

The Molecular Basis Of Diabetic Cardiomyopath, Ahmed Salaheldin Mustafa Ali Sultan

Dissertations

Diabetes mellitus (DM) is a major and worsening global health problem. Type 2 diabetes mellitus (T2DM) accounts for more than 90% of DM and the global epidemic of obesity largely explains the dramatic increase in the incidence and prevalence of T2DM over the past 20 years. Cardiovascular complications are the major cause of morbidity and mortality in diabetic patients. The electrocardiogram (ECG) of diabetic and obese patients is frequently disturbed. The aim of this project was to characterize and clarify the molecular basis of electro-mechanical dysfunction in the hearts of type 2 diabetic and type 2 diabetic/obese rats. Experiments were …

The Epidemiology And Burden Of Cardiometabolic Risk Factors In A Young Emirati Population, Fatima Abobakr Hussein Mezhal

Dissertations

The United Arab Emirates (UAE) has experienced rapid economic growth that was paralleled by a drastic rise in non-communicable diseases (NCDs); primarily cardiovascular diseases (CVDs), which account for 40% of mortality in UAE. CVDs have complex etiology, interplay, and accumulation of many risk factors. Understanding the clustering and interrelationships between common risk factors like obesity, deglycation, dyslipidemia, hypertension and central obesity, and the associations with social and lifestyle determinants are warranted. The study aimed to estimate the burden of cardiometabolic risk factors (CRFs), their interrelationship, and their associations with other social and lifestyle determinants in a young Emirati population. Data …

Prevalence, Characteristics And Correlates Of Prediabetes In Al Ain And Dubai, The Uae: Cross Sectional Study, Layla Mohamed Hassan Ali Al Marzooqi

Health and Physical Education Dissertations

The United Arab Emirates (UAE) has one of the highest rates of type 2 diabetes mellitus in the world. Prior to the onset of type 2 diabetes mellitus, a period of moderate hyperglycemia is often present, referred to as prediabetes. This is associated with a significant loss of pancreatic beta cells, an increased risk of cardiovascular disease and other serious health issues. There are gaps in the literature concerning the prevalence of prediabetes and its associated correlates, as well as correlations between the conversion rates from prediabetes to type 2 diabetes mellitus. The primary objective of this study was to …

Vitamin D Deficiency In Early Pregnancy, Diet And Physical Activity And Development Of Gestational Diabetes In Emirati Women, Sharifa Ali Abdulrahman Al Belooshi

Medical Education Dissertations

Vitamin D deficiency and Gestational Diabetes Mellitus (GDM) are common health problems among pregnant women in the Middle East region including the United Arab Emirates. However, a few prospective studies have investigated the association between vitamin D deficiency and the risk of GDM.

We estimated the incidence of GDM and examined the association of vitamin D status in early pregnancy and the development of GDM in Emirati pregnant women. In addition, we studied the association of diet, low physical activity and other covariates with the risk of GDM.

We conducted a prospective cohort study on Emirati pregnant women who visited …