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Touro College and University System

Theses/Dissertations

Autophagy

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The Effects Of Autophagy On The Replication Of Zika Virus, Mohammed Marghani May 2019

The Effects Of Autophagy On The Replication Of Zika Virus, Mohammed Marghani

NYMC Student Theses and Dissertations

Zika virus is an enveloped virus with a single-stranded positive-sense RNA genome. The Zika virus is a member of the Flaviviridae family of viruses that was discovered to infect humans in 1952. The Flavivirus envelope is decorated by many copies of two membrane proteins that facilitate viral entry. The virus is primarily transmitted through mosquito bites. Another method by which Zika virus could be transmitted is through sexual contact with Zika infected partners or from an infected pregnant woman to fetus known as congenital transmission. Infected patients suffer from self-limiting febrile illness including headaches, skin rash myalgia, and conjunctivitis. Zika …