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Articles 1 - 3 of 3
Full-Text Articles in Medicine and Health Sciences
The Effects Of Traumatic Stress & Role Of The Neuropeptide Y System As A Therapeutic In Females, Roxanna J. Nahvi
The Effects Of Traumatic Stress & Role Of The Neuropeptide Y System As A Therapeutic In Females, Roxanna J. Nahvi
NYMC Student Theses and Dissertations
The incidence of many stress-elicited disorders is markedly influenced by sex. Women are twice as likely as men to develop posttraumatic stress disorder (PTSD), depression, anxiety disorders, and social impairments following exposure to traumatic stress. However, most of the studies in animal models examining putative therapeutics for stress-triggered impairments, including single prolonged stress (SPS), were performed predominantly with males. Previous studies in males demonstrated that intranasal neuropeptide Y (NPY) can provide therapeutic relief of many SPS-triggered symptoms. Nevertheless, the overwhelming majority of studies found that NPY levels in females in many brain regions are lower than in male rodents. NPY …
“High Spending, Poor Productivity Gains!” Assessing Public Health System (In)Efficiency And Hospital Performance In The State Of Kuwait: Would More Private Delivery Improve Healthcare?, Aljawhara Alsabah
NYMC Student Theses and Dissertations
The healthcare sector in the State of Kuwait has been nurtured for many decades by the government, where the majority of health services in the country are controlled by the Ministry of Health (MoH). Although healthcare services in public sector hospitals are at highly subsidized rates, causing private sector involvement in healthcare to be considerably low, the growing demands for private delivery of care burgeoned participation of private hospitals in Kuwait, and improving hospital efficiency and productivity is more critical and timelier than ever. This dissertation aims to analyze public health system efficiency and hospital performance in the State of …
The Role Of G-Protein Coupled Receptor 75 In Pulmonary Hypertension, Catherine D'Addario
The Role Of G-Protein Coupled Receptor 75 In Pulmonary Hypertension, Catherine D'Addario
NYMC Student Theses and Dissertations
Pulmonary Hypertension (PH) is a cardiopulmonary disease estimated to affect between 20 million to 70 million individuals globally, with poor prognosis and inadequate treatment. Recent studies show the orphan G Protein Coupled Receptor 75 (GPR75) is upregulated in the pulmonary vessels of PH patients, especially in females. Therefore, we hypothesized that Gpr75 knock down (Gpr75-/-) mice will be protected from developing PH. To test our hypothesis, we challenged isolated intra-lobar pulmonary artery (IPA) from wild-type (WT; N=40) and Gpr75-/- (N=19) mice with hypoxia to examine their hypoxic vasoconstrictive (HPV) response, which is a physiological response of …