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Timely Diagnosis And Staging Of Non-Alcoholic Fatty Liver Disease Using Transient Elastography And Clinical Parameters., Christine Shieh, Dina L. Halegoua-De Marzio, Matthew L. Hung, Jonathan M. Fenkel, Steven K. Herrine
Timely Diagnosis And Staging Of Non-Alcoholic Fatty Liver Disease Using Transient Elastography And Clinical Parameters., Christine Shieh, Dina L. Halegoua-De Marzio, Matthew L. Hung, Jonathan M. Fenkel, Steven K. Herrine
Division of Gastroenterology and Hepatology Faculty Papers
Background and Aim: There is no standardized guideline to screen, image, or refer patients with non-alcoholic fatty liver disease (NAFLD) to a specialist. In this study, we used transient elastography (TE) to examine the fibrosis stages at which patients are first diagnosed with NAFLD. Subsequently, we analyzed metabolic markers to establish cut-offs beyond which noninvasive imaging should be considered to confirm NAFLD/non-alcoholic steatohepatitis fibrosis in patients.
Methods: Charts spanning July 2015-April 2018 for 116 NAFLD patients who had TE performed were reviewed. Univariate and multivariate analysis of metabolic markers was conducted.
Results: At the first hepatology visit, TE showed 73% …