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Full-Text Articles in Medicine and Health Sciences
Trust And Glycemic Control In Black Patients With Diabetic Retinopathy: A Pilot Study, Barry W. Rovner, Robin J. Casten
Trust And Glycemic Control In Black Patients With Diabetic Retinopathy: A Pilot Study, Barry W. Rovner, Robin J. Casten
Department of Psychiatry and Human Behavior Faculty Papers
Diabetic retinopathy (DR) is more prevalent in blacks than whites because, compared to whites, blacks on average have worse glycemic control. Both of these racial disparities reflect differences in sociocultural determinants of health, including physician mistrust. This randomized, controlled 6-month pilot trial compared the efficacy of a culturally tailored behavioral health/ophthalmologic intervention called Collaborative Care for Depression and Diabetic Retinopathy (CC-DDR) to enhanced usual care (EUC) for improving glycemic control in black patients with DR (n = 33). The mean age of participants was 68 years (SD 6.1 years), 76% were women, and the mean A1C was 8.7% (SD 1.5%). …
Medical Marijuana-Induced Tacrolimus Toxicity., Daniel Moadel, Keira Chism
Medical Marijuana-Induced Tacrolimus Toxicity., Daniel Moadel, Keira Chism
Department of Psychiatry and Human Behavior Faculty Papers
As both recreational and therapeutic marijuana use increases in the US, more attention is being paid to its direct medical and psychoactive effects. One crucial dimension is the potential for marijuana or marijuana-derived therapies to interact with other prescribed medications. Tacrolimus is an immunosuppressant medication prescribed to prevent rejection in patients receiving solid organ and bone marrow transplants. Clinically, it is characterized by a narrow therapeutic index and multiple drug-drug interactions. Constituents in marijuana are known to inhibit cytochrome P-450 3A, which is normally responsible for metabolizing tacrolimus, leading to the potential for a dangerous interaction. Though this phenomenon has …
Depressive Symptoms In People With Vision Impairment: A Cross-Sectional Study To Identify Who Is Most At Risk, Claire Nollett, Barbara Ryan, Nathan Bray, Catey Bunce, Robin J. Casten, Rhiannon Tudor Edwards, David Gillespie, Daniel J. Smith, Miles Stanford, Tom H. Margrain
Depressive Symptoms In People With Vision Impairment: A Cross-Sectional Study To Identify Who Is Most At Risk, Claire Nollett, Barbara Ryan, Nathan Bray, Catey Bunce, Robin J. Casten, Rhiannon Tudor Edwards, David Gillespie, Daniel J. Smith, Miles Stanford, Tom H. Margrain
Department of Psychiatry and Human Behavior Faculty Papers
Objective To identify the risk factors for significant depressive symptoms in people with visual impairment in England and Wales to provide information on who is most at risk and to whom support services could be targeted in future. Design A cross-sectional study using baseline data from a pragmatic randomised controlled trial. Setting and participants 990 participants aged 18 or over attending 1 of 14 low-vision rehabilitation primary care optometry-based clinics in South Wales or two hospital clinics in London. Outcome measure A score of ≥6 on the Geriatric Depression Scale-15 was classed as clinically significant depressive symptoms. Results In a …