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Articles 1 - 22 of 22
Full-Text Articles in Medicine and Health Sciences
The Effectiveness Of Treatments For Drug-Resistant Epilepsy: A Review Of Literature, Lauren Cummons
The Effectiveness Of Treatments For Drug-Resistant Epilepsy: A Review Of Literature, Lauren Cummons
Williams Honors College, Honors Research Projects
Many studies examine the treatment options for epilepsy; however, there is a lack of reviews compiling and evaluating the current treatments for drug-resistant epilepsy (DRE). This project aims to explore the existing body of research studies completed on treating DRE, evaluate the effectiveness of each treatment option, and assess what areas of research need more attention for future studies. Six primary DRE treatments from current research were thoroughly examined for this review. The quality of each treatment was evaluated based on the number of patients who had seizure freedom, had a seizure reduction, had adverse events, and had changes in …
Benefits And Drawbacks Of Pre-Licensure Clinical Jobs In Undergraduate Nursing Students, Rachael Muhlenkamp, Rebecca Trzecki, Jason Grassie
Benefits And Drawbacks Of Pre-Licensure Clinical Jobs In Undergraduate Nursing Students, Rachael Muhlenkamp, Rebecca Trzecki, Jason Grassie
Williams Honors College, Honors Research Projects
This research study aims to identify the benefits and drawbacks of pre-licensure clinical jobs in undergraduate nursing students. Many nursing students are encouraged to have a job in clinical settings in order to gain more experience. Many undergraduate nursing students here at the University of Akron currently have jobs in the clinical setting and these are the student's who we plan to use as our sample for this study. This study will be completed by spring of 2023, before graduation.
The Effects Of Exercise On Adolescents With Autism Spectrum Disorder, Julia Hofacker
The Effects Of Exercise On Adolescents With Autism Spectrum Disorder, Julia Hofacker
Williams Honors College, Honors Research Projects
This Honors Research Project will look at the impact of various types of exercise on the speech, language, and behavior of adolescents with autism spectrum disorder. The goal of this research project is to determine how exercise can be implemented into speech and therapy programs in order to better improve the communication skills of adolescents with autism spectrum disorder. To accomplish this, recent studies and publications will be analyzed to compare traditional therapy methods and therapy methods that include exercise. These studies will provide data on how various types of exercise impacted adolescents with autism spectrum disorder speech, language, behavior, …
Effectiveness Of Speech Intervention Methods In Children With Speech Delays, Andrea Noel, Rachel Windemuth, Brett Porter
Effectiveness Of Speech Intervention Methods In Children With Speech Delays, Andrea Noel, Rachel Windemuth, Brett Porter
Williams Honors College, Honors Research Projects
Speech delays in children is a common issue that can be treated by a wide variety of interventions. Our PICOT question is, in children, ages six months to thirteen years, with speech/language delays, how does the addition of innovative and supplemental interventions, compared with standard interventions alone, effect improvements in the delays. All three group members have known someone who has suffered from a speech delay, and we want to research the best possible methods to overcome that obstacle to answer our questions, we will begin to take on the task of creating and writing a systematic review. This review …
Amphisbaenian Head Movement And Burrowing Forces In Damp Granular Media, Jacob Newell
Amphisbaenian Head Movement And Burrowing Forces In Damp Granular Media, Jacob Newell
Williams Honors College, Honors Research Projects
Damp granular media is a difficult environment to study because it is both practically complex and it lacks equations which fully describe its behavior. In this study, an oscillatory lateral head movement and its effects while penetrating damp granular media were tested using a robophysical model. This experimental research was inspired by the burrowing behavior of the clade Amphisbaenia, a group of usually limbless squamates that employ a variety of different burrowing behaviors, but it can apply to a wide range of burrowers. This research could help with both human burrowing technologies and the further investigation of animal behaviors.
The Accuracy Of Recreational Athletes In Self Detecting Ventilation Threshold During A Maximal Exercise Test, Andrew Biegner
The Accuracy Of Recreational Athletes In Self Detecting Ventilation Threshold During A Maximal Exercise Test, Andrew Biegner
Williams Honors College, Honors Research Projects
INTRODUCTION: Ventilatory threshold (VT) is where minute ventilation (VE) increases nonlinearly with increasing exercise intensity. Prior studies have shown that subjects can recognize VT by changes in breathing during exercise. Teaching recreational athletes to use VT as a training method could result in better quality training. PURPOSE: Determine if recreational athletes can accurately perceive changes in ventilation associated with VT during maximal exercise testing. METHODS: Subjects were recruited (n=20, age= 20.5 ± 1.7 yrs.) to participate in the study. Subjects performed a modified maximal treadmill protocol with gas analysis. Subjects indicated when they noticed a considerable change …
Knockout Of Endospanin 1 Via Crispr In Zebrafish, Danio Rerio, Jared Kittinger
Knockout Of Endospanin 1 Via Crispr In Zebrafish, Danio Rerio, Jared Kittinger
Williams Honors College, Honors Research Projects
I made endospanin 1 knockout (KO) zebrafish to examine its effects on lipid and bone metabolism. Endospanin 1, or leptin receptor overlapping transcript (leprot), is a cytosolic protein linked to the protein hormone leptin that influences the trafficking of leptin receptors to the plasma membrane of cells. Genes for endospanin and tyrosinase (a pigmentation enzyme) were targeted via a microinjection of guide RNAs and CRISPR Cas9 into zebrafish embryos at 2-4 cell stages. I was able to disrupt the endospanin 1 gene (based upon the disruption of tyrosinase), but very few mutant zebrafish fully developed into adults. Only low KO …
Speech-Language Pathology Students' Perspective Of Working With Older Adults, Anna Hamill
Speech-Language Pathology Students' Perspective Of Working With Older Adults, Anna Hamill
Williams Honors College, Honors Research Projects
There is an increasing demand for speech language pathologists (SLPs) willing to work with older adults. Demographic trends warn that the number of people over 65 will double by 2050 (Vincent, 2010). Studies reveal that only 37.3% of SLP students prefer to work with older adults after graduation (Leonard et al., 2016). Ageism is affecting speech-language pathology and related health care professions. Research within the last five years has shown that ageism towards older adults exists across multiple medical professions in all fields and settings (Heape et al., 2020). Interdisciplinary fields report negative feelings towards older adults (Ortiz-Rubio et al., …
The Impact Of Bowl Feeding On Infant Muscle Activity And Kinematics - An Executive Summary, Kendall Steer
The Impact Of Bowl Feeding On Infant Muscle Activity And Kinematics - An Executive Summary, Kendall Steer
Williams Honors College, Honors Research Projects
Addressing difficulties with swallowing is a small, yet critical portion of a speech-language pathologist’s role. Infants often experience challenges associated with swallowing safely, yet the ability of SLPs to prescribe effective interventions is limited by the lack of knowledge on how anatomy and physiology interact to drive these challenges. The goal of my Honors Research Project is to address this lack of knowledge by determining how the infant pig tongue moves during feeding from a bottle versus drinking from a bowl, as well as how the muscles controlling the tongue differ in these behaviors. I used infant pigs for this …
Effects That The Methylenetetrahydrofolate Gene Mutation (Both The C677t And A1298c Polymorphisms) Have On Both Men And Women’S Fertility Abilities And Subsequent Fetal Development, As Well As What Nutritional Changes Can Possibly Do To Aid In Reversing These Supposed Negative Effects., Elizabeth Simkanin
Williams Honors College, Honors Research Projects
This study discusses the perceived negative effects of variants (C677T and A1298C) of the methylenetetrahydrofolate (MTHFR) gene on male and female fertility and fetal development, as well as the potential for nutrition changes to aid in reversing these negative effects. This research project was completed in order to discuss the possible association with and connection between nutrition and fertility in both male and female individuals who have either of the two most common MTHFR gene polymorphisms, 677C>T and 1298A>C. These two polymorphisms are of particular interest because they are associated with the most decreased activity of the MTHFR …
The Effects Of Sex On Zebrafish Bone Metabolism, Simon Bagatto
The Effects Of Sex On Zebrafish Bone Metabolism, Simon Bagatto
Williams Honors College, Honors Research Projects
I investigated the effects of diet and sex on zebrafish bone metabolism. Zebrafish were subjected to either a high-calorie or low-calorie diet over a five-week period. After this diet, zebrafish scales were used to measure alkaline phosphatase (ALP) and tartrate-resistant acid phosphatase (TRAP) enzyme activity with a fluorescent substrate. The enzyme activities were markers of the osteoblasts (ALP) and the osteoclasts (TRAP). These data were compared among sex and diet of the zebrafish using a repeated measures ANOVA statistical test. I also measured the number of resorption lacunae per scale (another indicator of osteoclast activity). The results showed higher TRAP …
Mouthpiece For Patients With Neuromuscular Disorders, Rebekah Starkey, Carissa Thompson, Michael Dickens, Andrew Pero
Mouthpiece For Patients With Neuromuscular Disorders, Rebekah Starkey, Carissa Thompson, Michael Dickens, Andrew Pero
Williams Honors College, Honors Research Projects
Neuromuscular Disorders (NMDs) impact people throughout the world. An early hallmark of these disorders includes some degree of facial muscle weakness. Respiratory testing is important to evaluate the progression of these patients’ NMDs. However, these tests require that the patient purses their lips around a mouthpiece to create a tight seal. This is a difficult task for one with facial muscle degeneration. This often leads to results that fail to reflect the patient’s true respiratory ability and prevents their physician from providing the appropriate degree of care. The objective of this project was to develop a face mask or mouthpiece …
Repeat Recall Test Literature Review, Carson Wolfe
Repeat Recall Test Literature Review, Carson Wolfe
Williams Honors College, Honors Research Projects
The Repeat Recall Test was created to assess a patient’s repeat, recall, tolerance, and effortfulness in communicating in different noise environments. This is important to audiology because there has never been a test that claims to assess these attributes all at once in a way that is realistic and efficient. For my project, I will be researching and writing a literature review on the Repeat Recall Test. Additionally, I will obtain a copy of the test and administer it to myself.
Access To Prenatal Care And Mental Health In Pregnant Women During Covid-19: A Systematic Review, Chloe Feezel, Marin Kahoun, Kaija Kunttu
Access To Prenatal Care And Mental Health In Pregnant Women During Covid-19: A Systematic Review, Chloe Feezel, Marin Kahoun, Kaija Kunttu
Williams Honors College, Honors Research Projects
COVID-19 affected the world in many ways. Pregnant women were greatly impacted by a change in their access to prenatal care, from in-person care to telehealth methods, and social support being limited by social isolation. Compared with prevalence of anxiety and depression in pregnant women pre-COVID-19, pregnant women during COVID-19 reported higher levels of anxiety and depression symptoms due to the stress of circumstantial changes. The purpose of this systematic review is to review and critically appraise the evidence about access to prenatal care and mental health in pregnant women during the COVID-19 pandemic. The following PICOT formatted question will …
Nicotine And E-Cigarette Effect On Maximal Metabolic Rate (Mmr) In Procambarus Clarkii, Nathan Cuttica
Nicotine And E-Cigarette Effect On Maximal Metabolic Rate (Mmr) In Procambarus Clarkii, Nathan Cuttica
Williams Honors College, Honors Research Projects
The use of electronic cigarettes, commonly referred to as e-cigarettes or vapes, has increased exponentially in recent years despite the lack of research into potentially negative physiological effects. The rise in e-cigarette use is likely due to the overwhelming evidence regarding the addictive properties of nicotine and the damage caused by traditional tobacco cigarettes. Most e-cigarettes, however, still contain nicotine and are associated with a rise in nicotine-related intoxications (Belkoniene et al., 2019). There are nicotine-free e-cigarette options, which are gaining popularity, but it is unknown if they carry similar or other negative physiological effects. Studies involving e-cigarettes containing nicotine …
The Passing Board, John Fitzgerald
The Passing Board, John Fitzgerald
Williams Honors College, Honors Research Projects
For my Honors Research Project I am taking a more personal route and looking to solve a childhood question/issue by designing a board that is small and easy to transport while also giving the best bounce pass possible. My proposed project would be a board that a soccer player can play a bounce pass onto and receive the ball from. The base of this design sounds simple enough, however, I would like to implement a way that the board can be adjusted to alter the angle of return of the soccer ball after the bounce. I also want to design …
Effects Of Electronic Cigarettes On The Standard Metabolic Rate Of Crayfish, Frank Shaffer
Effects Of Electronic Cigarettes On The Standard Metabolic Rate Of Crayfish, Frank Shaffer
Williams Honors College, Honors Research Projects
This study aims to examine the relationship between e-cigarettes (both with nicotine and without) and the effects on the standard metabolic rates of crayfish. In this experiment, 42 crayfish were divided into three treatment groups and exposed to a designated solution of either a control solution or a solution containing e-cigarette (nicotine or non-nicotine) vapor. Their standard metabolic rates were then measured by using oxygen uptake as a proxy. The results of this experiment indicate that there is no statistically significant relationship between the use of electronic cigarettes and the standard metabolic rate of crayfish. However, this study can be …
Cost-Benefit Analysis Of Increased Water Treatment Plant Service Goals On Reducing Water Quality Risk, Briton Polen, Kendra Sanner
Cost-Benefit Analysis Of Increased Water Treatment Plant Service Goals On Reducing Water Quality Risk, Briton Polen, Kendra Sanner
Williams Honors College, Honors Research Projects
To treat water to make it safe to drink, disinfection processes are used in water treatment plants. These disinfection processes produce disinfection byproducts (DBPs) through the reaction of organic matter and the disinfectant, such as chlorine. DBPs have been shown to pose a cancer risk to consumers. In this report, the focus is on two types of DBPs, trihalomethanes (THMs) and haloacetic acids (HAAs). The cancer risks associated with DBPs are analyzed through ingestion and inhalation pathways. Ingestion and inhalation consist of common water uses like drinking, cooking, or bathing. In addition to this, DBPs have been shown to increase …
Traumatic Brain Injury In Pediatrics, Natalie Deibel
Traumatic Brain Injury In Pediatrics, Natalie Deibel
Williams Honors College, Honors Research Projects
Traumatic Brain Injury (TBI) is an acquired brain injury as a result of an external force to the head. Common causes for these injuries include falls, motor vehicle accidents, sports, and abuse. The affected location of the brain, severity, and age at the time of injury affect what deficits are present. Resulting deficits can be in speech, language, behavior, motor, and cognition/executive functions (Manasco, 2020). Traumatic brain injuries can affect all ages. No parent wants to experience their child going through this. TBIs do not just affect the patient but also loved ones. During this difficult time, parents or caregivers …
Health Misinformation During Epidemiological Crises, Bethany Stefan, Alexis L. Emich, Katrina R. Lamp
Health Misinformation During Epidemiological Crises, Bethany Stefan, Alexis L. Emich, Katrina R. Lamp
Williams Honors College, Honors Research Projects
Health misinformation is more prevalent than ever in the modern age and poses serious risks for those who believe it. Medical fallacies can become especially harmful during periods of widespread disease when the misinformed respond in ways that increase threats to public health. The purpose of this systematic review is to describe and critically appraise the evidence about how health misinformation during endemics and pandemics can influence behaviors and responses, as well as the implications of interventions affecting these behaviors. A systematic search of the literature with inclusion/exclusion criteria using CINAHL Plus with Full Text, MEDLINE, and PsychINFO resulted in …
Enhancing Dental Aligners With Direct 3d Printing Manufacturing, Erin Clark, Lauren Ickes, Tyler Madison
Enhancing Dental Aligners With Direct 3d Printing Manufacturing, Erin Clark, Lauren Ickes, Tyler Madison
Williams Honors College, Honors Research Projects
Replacement of thermoforming with direct 3d printed aligners, molding appliances for dental and alveolar movement. Currently the process involved requires 3d printing models and plastic thermoforming, trimming and polishing to fabricate the end product. If possible a product that could be 3d printed that had stress retention, crack resistance, and stain resistance properties delivered in thickness between .030 and .040 inches.
Reducing Placental Oxidative Stress In A Rat Model Preeclampsia Using Vegfr2 Nanoparticles, Sophia Ganios
Reducing Placental Oxidative Stress In A Rat Model Preeclampsia Using Vegfr2 Nanoparticles, Sophia Ganios
Williams Honors College, Honors Research Projects
Preeclampsia is a complication of pregnancy, where the placenta lacks sufficient blood flow due to abnormal formation of the vascular endothelial cells. This results in hypertension and increased reactive oxygen species, causing oxidative stress. The VEGF (vascular endothelial growth factor) helps develop new growth, so by increasing the receptors VEGFR2 by injection of LTP nanoparticles into the uterine wall of RUPP rats, one can see if there would be improvement in the otherwise reduced uterine pressure pregnant rat. This would be confirmed by the 8-isoprostane test, which measures oxidative stress.