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Full-Text Articles in Medicine and Health Sciences

Comparison Of Auto-Adjusting And Fixed Level Continuous Positive Airway Pressure Therapy In Patients With Mild To Moderate Obstructive Sleep Apnoea Hypopnoea Syndrome, Geraldine Nolan Nov 2004

Comparison Of Auto-Adjusting And Fixed Level Continuous Positive Airway Pressure Therapy In Patients With Mild To Moderate Obstructive Sleep Apnoea Hypopnoea Syndrome, Geraldine Nolan

Masters

Obstructive Sleep Apnoea Hypopnoea syndrome (OSAHS) is a potentially serious medical disorder associated with increased morbidity and mortality. It is estimated to affect 4% of males and 2% of females between the ages of forty and sixty. Nasal continuous positive airway pressure (CPAP) is the first choice treatment for this condition and it is extremely effective at controlling OSAHS. However, not all patients can tolerate this therapy, in particular those within the mild to moderate category, and there are also many others who are unable to comply with the minimum usage requirements of at least four hours every night. A …


A System For Monitoring Pressures And Spinal Curvature In Spinally Injured People Immobilised On A Spinal Raft, Ruairí De Fréin, Eoin Flinn, Ted Burke May 2004

A System For Monitoring Pressures And Spinal Curvature In Spinally Injured People Immobilised On A Spinal Raft, Ruairí De Fréin, Eoin Flinn, Ted Burke

Articles

We present a system designed to study the pressure at various ‘hot spots’ on the back of the body and the deformation of the spine experienced by a patient when strapped to a spinal board, and the potential alleviation of both by the addition of an inflatable “spinal raft” (or other similar device). In measuring pressure we devised a system of air-filled sacks interfaced with a PC. Each sack, placed under a particular key point on the body, is inflated until its faces just begin to separate and a switch thereby opens. The pressure reading is then captured and displayed …


Ionizing Radiation Induces A Stress Response In Primary Cultures Of Rainbow Trout Skin, Fiona Lyng, M. Lyons-Alcantara, P. Owell, Sharon Ni Shuilleabhain, Colin Seymour, D. Cottell, Carmel Mothersill Jan 2004

Ionizing Radiation Induces A Stress Response In Primary Cultures Of Rainbow Trout Skin, Fiona Lyng, M. Lyons-Alcantara, P. Owell, Sharon Ni Shuilleabhain, Colin Seymour, D. Cottell, Carmel Mothersill

Articles

Fish skin is very vulnerable to damage from physical and chemical pollutants because it is in direct contact with the aquatic environment. In this study, the effect of g radiation on primary cultures of rainbow trout skin was investigated. Primary cultures containing two cell types, epidermal cells and goblet mucous cells, were exposed to doses ranging from 0.5–15 Gy 60Co g radiation. Expression of PCNA, c-myc and BCL2 was investigated as well as growth and levels of apoptosis and necrosis. Morphological and functional changes were also studied. The irradiated cultures showed evidence of a dose-dependent increase in necrosis and enhanced …


A Generic Approach To Supporting The Management Of Computerised Clinical Guidelines And Protocols, Kudakwashe Dube Jan 2004

A Generic Approach To Supporting The Management Of Computerised Clinical Guidelines And Protocols, Kudakwashe Dube

Doctoral

Clinical guidelines or protocols (CGPs) are statements that are systematically developed for the purpose of guiding the clinician and the patient in making decisions about appropriate healthcare for specific clinical problems. Using CGPs is one of the most effective and proven ways to attaining improved quality, optimised resource utilisation, cost containment and reduced variation in healthcare practice. CGPs exist mainly as paper-based natural language statements, but are increasingly being computerised. Supporting computerised CGPs in a healthcare environment so that they are incorporated into the routine used daily by clinicians is complex and presents major information management challenges. This thesis contends …