Medicine and Health Sciences Commons^™

Development Of Holographic Optical Elements For Use In Wound Monitoring, Pamela Stoeva, Tatsiana Mikulchyk, Brian Rogers, M. Oubaha, Suzanne Martin, Dervil Cody, M.A. Ferrara, G. Coppola, Izabela Naydenova

Conference Papers

Wounds that fail to heal impact the quality of life of 2.5 % of the total population. The costs of chronic wound care will reach $15–22 billion by 2024. These alarming statistics reveal the financial strain for both the medical industry and society. A solution can be found in compact and accessible sensors that offer real-time analysis of the wound site, facilitating continuous monitoring and immediate treatment, if required. Benefits of these sensors include reduction of cost and can extend the reach of healthcare to remote areas. The progression of a wound site can be closely monitored with holographic optical …

Eyecare Practitioner Reluctance To Fit Children With Contact Lenses, Claire E. Mcdonnell

Conference Papers

Purpose: Myopia control strategies in the form of contact lenses and spectacles have been commercially available to eyecare practitioners in the Republic of Ireland (RoI) since 2017 and 2021 respectively. The aim of this research was to determine the level of adoption of these strategies among independent eyecare practitioners in the RoI.

Methods: In order to establish the number of practices offering myopia control contact lenses, examination of independent practices’ websites was made to see whether or not they mentioned myopia control. Phone calls were made to practices identified in this way, to ascertain if they were actually offering myopia …

Corneal Sensitivity In Normal Subjects As Measured Using The Cochet-Bonnet Aesthesiometer, Claire E. Mcdonnell, Clara Boland, Kayinat Khalid, Muno Osman

Conference Papers

Aim: The aims of this research were; to establish a range of values for corneal sensitivity in normal subjects as measured using the Cochet-Bonnet aesthesiometer; to determine if the measurement of corneal sensitivity in one eye affected subsequent measurements in the fellow eye; and to determine if there is a difference in corneal sensitivity between fellow eyes.

Methods: Thirty four subjects aged between 18 and 30 who did not wear contact lenses had their central corneal sensitivity measured in both eyes. The average of three readings was taken as the measurement for each eye. In 15 subjects, measurement was taken …

In-Vitro Screening Of Immune Response With Ftir Spectroscopy In A Mirna Murine Knock Out Model, Ryan Muddiman, Abigail Keogan, Daniel Cullen, Remsha Afzal, Frances Nally, Claire Mccoy, Aidan Meade

Conference Papers

MicroRNAs are small ~22 nucleotide RNA sequences that are guided to the 3’ untranslated region (UTR) of protein-coding target mRNA sequences. One particular microRNA, miR155, plays a remarkable role in the immune system, where it is essential for mounting appropriate immune responses. However, its dysregulation has been identified in multiple inflammatory disorders such as Multiple Sclerosis (MS), arthritis, psoriasis and colitis. More specifically, miR-155 has been found to be elevated in the serum and brain lesions of MS patients. Importantly, therapeutic inhibition of miR-155 can inhibit progression of the MS disease model. One of us has identified that macrophages are …

Progressive Lenses And Acute Anisomentropia, Alena Lane

Conference Papers

The aim of the poster is to demonstrate that presbyopic patients with acute anisometropia can continue using progressive lenses. Acute or induced anisometropia occurs when a sudden change in the prescription is introduced. A typical example of this occurs following the cataract operation to one eye. The problem arises when the difference in refractive power of both eyes after the operation is 2.00D and more. The difference in lens power can cause the eyes to see different size images and lead to difficulties in fusing them. Additionally, when an image is viewed off axis through the spectacle lens away from …

Nutrition Policy: Developing Scientific Recommendations For Food-Based Dietary Guidelines For Older Adults Living Independently In Ireland, Oonagh C. Lyons, Mary A.T. Flynn, Clare A. Corish, Eileen R. Gibney, Maeve A. Kerr, Malachi J. Mckenna, Helene Mcnulty, Emeir M. Mcsorley, Anne P. Nugent, Claire O'Brien, Mary Ward, Katherine Younger, Ita Saul

Conference Papers

Older adults (≥65 years) are the fastest growing population group. Thus, ensuring nutritional well-being of the ‘over-65s’ to optimise health is critically important. Older adults represent a diverse population – some are fit and healthy, others are frail and many live with chronic conditions. Up to 78% of older Irish adults living independently are overweight or obese. The present paper describes how these issues were accommodated into the development of food-based dietary guidelines for older adults living independently in Ireland. Food-based dietary guidelines previously established for the general adult population served as the basis for developing more specific recommendations appropriate …

Precision Medicine And Novel Therapeutic Strategies In Detection And Treatment Of Cancer: Highlights From The 58th Iacr Annual Conference, Sean Kennedy

Conference Papers

Innovation in both detection and treatment of cancer is necessary for the constant improvement in therapeutic strategies, especially in patients with novel or resistant variants of cancer. Cancer mortality rates have declined by almost 30% since 1991, however, depending on the cancer type, acquired resistance can occur to varying degrees. To combat this, researchers are looking towards advancing our understanding of cancer biology, in order to inform early detection, and guide novel therapeutic approaches. Through combination of these approaches, it is believed that a more complete and thorough intervention on cancer can be achieved. Here, we will discuss the advances …

What Type Of Soft Contact Lens Works Best For Reverse Piggyback?, Claire E. Mcdonnell, Emma Chaney, Tara Kennedy, Aoife Farrell

Conference Papers

Aim

To determine which type of soft contact lens works best in a reverse piggyback lens system.

Background

A reverse piggyback lens system comprises of a soft contact lens worn over a rigid gas permeable lens. Several uses of this system include prevention of rigid gas permeable lens decentration during sporting activities and reduction of rigid gas permeable lens intolerance due to lid sensitivity.

Methods

Four different types of soft contact lenses; Senofilcon A, Omafilcon A, Etafilcon A and Delefilcon A, were assessed in a reverse piggyback system, in both eyes of twelve subjects (n=24). Over refraction, best corrected visual …

Direct Multiplexing Of Low Order Aberration Modes In A Photopolymerbased Holographic Element For Analog Holographic Wavefront Sensing, Emma Branigan, Suzanne Martin, Matthew Sheehan, Kevin Murphy

Conference Papers

The fabrication of an analog holographic wavefront sensor, capable of detecting the low order defocus aberration, was achieved in an acrylamide-based photopolymer. While other implementations of holographic wavefront sensors have been carried out digitally, this process utilises a recording setup consisting only of conventional refractive elements so the cost and complexity of holographic optical element (HOE) production could be much reduced. A pair of diffraction spots, corresponding to a maximum and minimum amount of defocus, were spatially separated in the detector plane by multiplexing two HOEs with different carrier spatial frequencies. For each wavefront with a known aberration that was …

Myopia Control In The Republic Of Ireland, Claire E. Mcdonnell, Adebola Obadare, Muno Osman, Sinead Redmond

Conference Papers

Purpose: to estimate how many independent optical practices in the Republic of Ireland (ROI) are offering myopia control options to patients and parents.

Methods: 346 independent optical practices were identified in the ROI using a listing provided on the Association of Optometrists Ireland website. All practices identified were emailed to ask if they practised any myopia control. Practice websites (where available) were examined to see if myopia control was mentioned as a service offered. Some practices believed to be offering myopia control were phoned directly to ascertain if they were practising myopia control. This research was carried out between Feb …

Optimisation Of The Performance Of Holographic Beam-Shaping Diffractive Diffusers Through Refinement Of The Recording Process, Cara Jones, Suzanne Martin, Sanjay Keshri, Dervil Cody, Kevin Murphy

Conference Papers

Optical diffusers have uses in laser applications and machine vision. Typical fabrication at a commercial level requires master production and the stamping/copying of individual elements at scale. This expensive, indirect process inhibits custom diffusers at reasonable cost. Previously the authors published a novel, direct, single beam method of recording customizable and controllable volume holographic diffusers by manipulating laser speckle and recording the pattern in photopolymer. This method allows for beam-shaping to produce diffusion patterns of various sizes and shapes. In this work, the direct method of recording controllable holographic diffusers is refined to improve diffuser performance (i.e., a decrease in …

A Comparison Of Dietary Intake Of Children/Adolescents With And Without Myopia, Niamh Burke, John Butler, Daniel Ian Flitcroft, James Loughman

Conference Papers

Myopia is caused by an eye which has grown too long. The prevalence of myopia has increased drastically in recent years and half of the world’s population is expected to be myopic by 2050.(1) Consequently, a significant increase in sight threatening diseases will follow.(1) Myopia most commonly develops in youth, and we now know that environmental factors affect its development. Nutritional status strongly influences growth and development, including that of the eye. It has been hypothesised, therefore, that nutrition may play a role in this excessive eye growth. Current findings are conflicted, with a clear gap in the evidence.(2,3) Therefore, …

An Investigation Of Therapeutic Rapport Through Prosody In Brief Psychodynamic Psychotherapy, Carolina De Pasquale, Charlie Cullen, Brian Vaughan

Conference Papers

Therapeutic alliance, a concept closely related to rapport, is one of the most important variables in psychotherapy. High degrees of synchrony/coordination in the therapeutic session are considered to contribute to rapport, and have received attention in the psychotherapy literature. Coordinative behaviours are observable in speech, and they manifest in phenomena such as prosodic accommodation, a dynamic phenomenon closely related to conversational success. A preliminary investigation of interpersonal prosodic dynamics in psychotherapy was performed on a database obtained in collaboration with the University of Padua, consisting of 16 recordings making up the entire course of a brief psychodynamic psychotherapy intervention for …

Investigating Prosodic Accommodation In Clinical Interviews With Depressed Patients, Brian Vaughan, Carolina De Pasquale, Lorna Wilson, Charlie Cullen, Brian Lawlor

Conference Papers

Six in-depth clinical interviews, involving six elderly female patients (aged 60+) and one female psychiatrist, were recorded and analysed for a number of prosodic accommodation variables.

Our analysis focused on pitch, speaking time, and vowel-space ratio. Findings indicate that there is a dynamic manifestation of prosodic accommodation over the course of the interactions. There is clear adaptation on the part of the psychiatrist, even going so far as to have a reduced vowel-space ratio, mirroring a reduced vowel-space ratio in the depressed patients. Previous research has found a reduced vowel-space ratio to be associated with psychological distress; however, we suggest …

A Multi-Method Scheduling Framework For Medical Staff, Wael Rashwan, John Fowler, Amr Arisha

Conference Papers

Hospital planning teams are always concerned with optimizing staffing and scheduling decisions in order to improve hospital performance, patient experience, and staff satisfaction. A multi-method approach including data analytics, modeling and simulation, machine learning, and optimization is proposed to provide a framework for smart and applicable solutions for staffing and shift scheduling. Factors regarding patients, staff, and hospitals are considered in the decision. This framework is piloted using the Emergency Department(ED) of a leading university hospital in Dublin. The optimized base staffing patterns and shift schedules actively contributed to solving ED overcrowding problem and reduced the average waiting time for …

Comparison Of Two Methods Of Determining Central Corneal Vault Under A Scleral Lens: Estimation By Slit Lamp Biomicroscope And Anterior Segment Oct, Claire E. Mcdonnell, Darragh O'Donnell, Lynn O'Mara, Shannon Power

Conference Papers

Purpose: The aim of this study was to ascertain if there is agreement in the measurement of central corneal vault (CCV) under a scleral lens, between estimations made using a slit lamp biomicroscope (SLB) and measurements made using anterior segment optical coherence tomography (AS-OCT).

Method: 30 images were taken of CCV under various scleral lenses using a SLB and an AS-OCT. Estimations of CCV from SLB photographs were made using known thicknesses of the scleral lenses used and imagej software. The in-built measurement callipers was used to measure CCV on the AS-OCT. Right eyes were imaged on the AS-OCT first …

Development Of Sensitive Holographic Devices For Physiological Metal Ion Detection, Sabad-E- Gul, Suzanne Martin, John Cassidy, Izabela Naydenova

Conference Papers

The development of selective alkali metal ions sensors in particular is a subject of significant interest. In this respect, the level of blood electrolytes, particularly H+, Na+, K+ and Cl- , is widely used to monitor aberrant physiologies associated with pulmonary emphysema, acute and chronic renal failure, heart failure, diabetes. The sensors reported in this paper are created by holographic recording of surface relief structures in a self-processing photopolymer material. The structures are functionalized by ionophores dibenzo-18-crown-6 (DC) and tetraethyl 4-tert-butylcalix[4]arene (TBC) in plasticised polyvinyl chloride (PVC) matrix. Interrogation of these structures by light allows indirect measurements of chemical analytes’ …

Strain Distribution In The Porcine Lumbar Laminae Under Asymmetric Loading, Colin Bright, Stephen Tiernan, Fiona Mcevoy, Patrick Kiely

Conference Papers

If the articular facets of the vertebra grow in an asymmetric manner, the developed geometry causes an asymmetry of loading. When the loading environment is altered by way of increased activity, the likelihood of acquiring a stress fracture may be increased. The combination of geometric asymmetry and increased activity is hypothesised to be the precursor to the stress fracture under investigation in this study, spondylolysis. This vertebral defect is an acquired fracture with 7% prevalence in the paediatric population. This value increases to 21% among athletes who participate in hyperextension sports. Tests were carried out on porcine lumbar vertebrae, on …

A Pilot Study Of Comparison Gesture Analysis In Motion Driven Video Games, Fabrizio Valerio Covone, Brian Vaughan, Charlie Cullen

Conference Papers

This study investigates whether there are significant differences in the gestures made by gamers and non-gamers whilst playing commercial games that employ gesture inputs. Specifically, the study focuses on testing a prototype of multimodal capture tool that we used to obtain real-time audio, video and skeletal gesture data. Additionally, we developed an experimental design framework for the acquisition of spatio-temporal gesture data and analysed the vector magnitude of a gesture to compare the relative displacement of each participant whilst playing a game.

A Collagen‐Glycosaminoglycan‐Fibrin Scaffold For Heart Valve Tissue Engineering Applications, Claire Brougham, Stefan Jockenhoevel, Thomas Flanagan, Fergal O'Brien

Conference Papers

The field of heart valve biology and tissue engineering a heart valve continue to expand. The presentatio ns at this meeting reflect the advances made in both areas due to the multi-disciplinary approach taken by many laboratories.

A New Reinforced Fibrin Collagen Glycosaminoglycan Material To Resist Tissue Contraction In Heart Valves, Claire Brougham, Gerard Cooney, Stefan Jockenhoevel, Thomas Flanagan, Fergal O'Brien

Conference Papers

A crosslinked, multicomponent scaffold of collagen, GAG and fibrin has been characterised for heart valve applications. Fibrin gels reinforced with a 0.75% collagen, 0.044% GAG scaffolds can resist VSMC induced contraction significantly more than fibrin-only gels, while allowing cell proliferation and maintaining excellent cell viability. This improvement in structural integrity may facilitate the use of fibrin based materials for heart valve tissue engineering.

An Economic Analysis Of The Impact Of Refractive Error In Mozambique, Stephen Thompson

Conference Papers

Mozambique eyecare project carried out in June 2013 to estimate the socio-economic benefit of an Optometry Programme by calculating the benefits of addressing refractive error in terms of productivity gained as a result of the intervention.

Considerations In The Design Of An Eye Health Programme For Nampula, Mozambique, Aoife Phelan, Lisa O'Donoghue, Kovin Naidoo, Kathryn Saunders, James Loughman

Conference Papers

Introduction/Purpose:

There are almost twelve million children (<18 >years) in Mozambique with minimal access to eye care. [1] Annual screening of school children by teachers for uncorrected refractive error is one of the most cost effective health interventions in Sub Saharan Africa.[2] The International Agency for the Prevention of Blindness (IAPB) has recommended that child eye health interventions be incorporated into National School Health Initiatives.[3]

In view of the IAPB position this presentation sets out to identify and discuss the main considerations in the design of a child eye health strategy, for the province of Nampula, Mozambique, which aligns itself …

Evaluations Of Exit Competencies Of Optometrists In Mozambique, Kajal Shah, James Loughman

Conference Papers

Introduction: The appropriate education for eye health workers is a key determinant of sustainable eye health care systems, and the solution to avoidable blindness and visual impairment. The Mozambique Eye care Project (MEP), is developing the country's first indigenously trained optometrists using a competency-based education curriculum.

Aims: The principal aim is to evaluate the exit clinical competencies of the first optometry graduates in Mozambique and to inform the evaluation of the competency curriculum.

Methods: Using UK based competencies as a benchmark; nine final year students were examined to assess competences in six core subjects.Further information about factors relating to their …

The Development Of A Public Optometry System In Mozambique: A Cost Benefit Analysis, Stephen Thompson, James Loughman

Conference Papers

No abstract provided.

Towards Leaner Healthcare Facility: Application Of Simulation Modelling And Value Stream Mapping, Waleed Abo Hamad, John Crowe, Amr Arisha

Conference Papers

Recently, the application of lean thinking in healthcare has grown significantly in response to rising demand caused by population growth, ageing and high expectations of service quality. However, insufficient justifications and lack of quantifiable evidence are the main obstacles to convince healthcare executives to adopt lean. Therefore, this paper presents a methodology that integrates lean tools with simulation to enhance the quality of patient care in healthcare facilities. This enables healthcare organisations to dedicate more time and effort to patient care without extra cost to the organisation or to the patient. Value stream mapping is used to identify value-added and …

Student Experience In Optometry Education In Mozambique: Initial Challenges In An International Collaborative Program, Kajal Shah

Conference Papers

Purpose:

One of the solutions to creating sustainable eye care structures is education of personnel. Mozambique currently has only 17 ophthalmologists for a population of 21 million and 34 trained Ophthalmic Technicians, the only two providers of refraction services within the local health system. There are no optometrists. The Mozambique Eyecare Project is funding the training of the country’s first optometrists at the University of Lurio in Nampula, Mozambique. Their core competencies will be evaluated with a view to creating best practise in education in a developing world environment.

Method:

This is a longitudinal evaluation of the refraction competencies …

Faculty Requirement For A Portuguese Language Optometry Program: Experience And Challenges Of The Mozambique Eye Care Project, Diane Wallace

Conference Papers

Faculty recruitment for a Portuguese-language optometry program: experiences and challenges of The Mozambique Eye Care Project

Ms Diane Wallace BOptom, MPA

University of KawZulu Natal, South Africa

Purpose

The Mozambique Eyecare Project (MEP) is a unique institutional collaboration in a programme for the development, implementation and evaluation of a regional optometry training model for Portuguese-speaking Africa. The Project was initiated in February 2009 with the first cohort of undergraduate students beginning classes at Lúrio University in Northern Mozambique. This is the first Portuguese-language optometry program in Africa, and with no professionally qualified optometrists locally, faculty had to be recruited from …

Primary School Vision Screening Involving Teachers In Nampula, Mozambique., Aoife Phelan

Conference Papers

Purpose

There is no plan for a national child eye care programme or existing human resource infrastructure to address the immediate challenge of child eye health in Mozambique. Furthermore, the prevalence and incidence of refractive error, visual impairment (VI) and child blindness (CB) in Mozambique is unknown. VI and CB have devastating personal, developmental, economic and other implications for the child, the family, the community and indeed, the nation. This study aims to design, implement and evaluate a school based paediatric vision screening service, to identify those in need of eye health services, among Mozambique’s 11,561,000 children.

Methods

Primary School …

Evaluation Of Refraction Skills And Competencies Of Ophthalmic Technicians:Providers Of Refractive Services In Mozambique, Kajal Shah, James Loughman

Conference Papers

Purpose

Approximately 314 million people worldwide live with low vision and blindness.145 million people's low vision is due to uncorrected refractive errors¹.One of the solutions to creating sustainable eye care structures is education of personnel².

The Technological University Dublin (DIT) with ICEE (International Centre of Eyecare Education) is developing and implementing a sustainable model for optometric education and eye care service delivery in Unilurio in Mozambique.The Mozambique Eyecare Project aims to train Mozambique’s first professional optometrists who will provide a sustainable and comprehensive eye-care system as an integral part of the national health system³. …