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Associations Between Low Back Pain, Disability, Functional Status, And Serum Interleukin-1 \Beta Level, Ali̇ Aydeni̇z, Teki̇n Karsligi̇l, Savaş Gürsoy

Turkish Journal of Medical Sciences

Aim: In the past the role of biochemical mediators of inflammation in back pain received little attention. The purpose of the present study was to examine the association between serum IL-1 \beta level in patients with low back pain (LBP) and its effect on their functional status. Methods: This cross-sectional study included 88 LBP patients with symptom duration of 6 months or longer and 65 healthy controls. Serum analysis was performed using ELISA. The LBP group completed the Roland-Morris Disability Questionnaire and Oswestry Disability Index in order to evaluate their functional status. Results: Mean IL-1 \beta level was significantly higher …