Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 12 of 12
Full-Text Articles in Medicine and Health Sciences
Evidence-Based Information About Intermittent Fasting In Diabetes Patients: Useful Or Harmful?, Mustafa Altay
Evidence-Based Information About Intermittent Fasting In Diabetes Patients: Useful Or Harmful?, Mustafa Altay
Turkish Journal of Medical Sciences
Background/aim: One of the most important components of treatment for diabetic patients is diet and healthy nutrition therapy. Calorie restriction is effective and without cost increases its appeal for both patients and physicians. Unfortunately, continuous calorie restriction is a difficult method. For this reason, alternative calorie restriction methods, such as intermittent fasting (IF), have been investigated by some researchers. Materials and methods: IF refers to a wide range of diet programmes covering periods of eating and fasting, which vary according to the different regimens. In this article, first, some general information will enable us to understand the concept of IF, …
Are Disease-Related Symptoms Important To Predicting Developing Diabetes From Prediabetes?, Si̇bel Engi̇n, Tolga Akkan, Murat Dağdevi̇ren, Ti̇jen Şengezer, Mustafa Altay
Are Disease-Related Symptoms Important To Predicting Developing Diabetes From Prediabetes?, Si̇bel Engi̇n, Tolga Akkan, Murat Dağdevi̇ren, Ti̇jen Şengezer, Mustafa Altay
Turkish Journal of Medical Sciences
Background/aim: There are not many studies conducted to detect and recognize the symptoms during the prediabetes period. In our study, we aimed to determine the symptoms that can be seen in prediabetes and diabetes and their prevalence and to determine the similarities and differences between the two groups. Materials and methods: Individuals who were diagnosed with prediabetes or diabetes, over the age of 18, literate, and accepted to collaborate were included in our study. The "Diabetes Symptoms Checklist Scale" was used by interviewing 321 participants, 161 prediabetic and 160 diabetic, face-to-face. Results: It has been found that the most common …
Correlations Between Glycosylated Hemoglobin And Glucose Levels In Chinese Older Adults With Newly Diagnosed Type 2 Diabetes Mellitus, Yun Yu, Jun Yang, Wei Tang
Correlations Between Glycosylated Hemoglobin And Glucose Levels In Chinese Older Adults With Newly Diagnosed Type 2 Diabetes Mellitus, Yun Yu, Jun Yang, Wei Tang
Turkish Journal of Medical Sciences
Background/aim: To explore the correlations between glycosylated hemoglobin (HbA1c) and glucose levels in older adults with newly diagnosed type 2 diabetes mellitus (T2DM). Materials and methods: A total of 783 participants aged ≥60 years were enrolled. The 75-g oral glucose tolerance test (OGTT) was conducted and HbA1c was measured. The participants were divided into normal glucose tolerance (NGT)HbA1c, Pre-DMHbA1c, and T2DMHbA1c groups based on the HbA1c diagnostic criteria. The correlations between HbA1c and glucose levels of the OGTT were analyzed. Results: When HbA1c ≥ 6.5% in older people, HbA1c was positively correlated with Glucose 0 min and 120 min of …
The Survival Outcomes And Prognostic Factors Of Hepatocellular Carcinoma Among Type 2 Diabetes Patients: A Two-Centre Retrospective Cohort Study, Noor Atika Azit, Shahnorbanun Sahran, Voon Meng Leow, Manisekar K. Subramaniam, Suryati Mokhtar, Azmawati Mohammed Nawi
The Survival Outcomes And Prognostic Factors Of Hepatocellular Carcinoma Among Type 2 Diabetes Patients: A Two-Centre Retrospective Cohort Study, Noor Atika Azit, Shahnorbanun Sahran, Voon Meng Leow, Manisekar K. Subramaniam, Suryati Mokhtar, Azmawati Mohammed Nawi
Turkish Journal of Medical Sciences
Background/aim: To determine the survival outcomes and prognostic factors associated with hepatocellular carcinoma (HCC) survival in type 2 diabetes (T2D) patients. Materials and methods: This was a retrospective cohort study involving two hepatobiliary centres from January 1, 2012, to June 30, 2018. Medical records were analysed for sociodemographic, clinical characteristics, laboratory testing, and HCC treatment information. Survival outcomes were examined using the Kaplan?Meier and log-rank test. Prognostic factors were determined using multivariate Cox regression. Results: A total of 212 patients were included in the study. The median survival time was 22 months. The 1-, 3-, and 5-year survival rates were …
The Evaluation Of Intracellular Energy Metabolism In Prediabetic Patients And Patientsnewly Diagnosed With Type 2 Diabetes Mellitus, Erkan Dulkadi̇roğlu, Hüseyi̇n Özden, Hüseyi̇n Demi̇rci̇
The Evaluation Of Intracellular Energy Metabolism In Prediabetic Patients And Patientsnewly Diagnosed With Type 2 Diabetes Mellitus, Erkan Dulkadi̇roğlu, Hüseyi̇n Özden, Hüseyi̇n Demi̇rci̇
Turkish Journal of Medical Sciences
Background/aim: Increased susceptibility to infections is a serious problem in diabetics. Impairment in the energy metabolism of the immune system is the main source of the problem. Early diagnosis of the impairment in energy metabolism is crucial. Our study aimed to investigate the energy metabolism in leukocytes in patient groups such as prediabetics and patients newly diagnosed with type 2 diabetes mellitus. Materials and methods: Our study included 21 newly diagnosed type 2 diabetic patients (NDDP), 30 prediabetic patients, and 22 adult volunteers. 75 g oral glucose tolerance test (OGTT) was applied to all patients included in the study. Blood …
Effect Of Treatment Of Iron Deficiency Anemia Onhemoglobin A1c In Type 2 Diabetic Patients, Ensieh Nasli-Esfahani, Bagher Larijani, Peyvand Amini, Robabeh Ghodsi Ghasemabadi, Rezvan Razmandeh
Effect Of Treatment Of Iron Deficiency Anemia Onhemoglobin A1c In Type 2 Diabetic Patients, Ensieh Nasli-Esfahani, Bagher Larijani, Peyvand Amini, Robabeh Ghodsi Ghasemabadi, Rezvan Razmandeh
Turkish Journal of Medical Sciences
Background/aim: Iron deficiency anemia (IDA) affects hemoglobin A1c (HbA1c) levels. This study aimed to evaluate the effect of treatment of iron deficiency anemia on hemoglobin A1c in type 2 diabetic patients.Materials and methods: Ninety type 2 diabetes mellitus (T2DM) patients with IDA were included in a randomized, placebo-controlled, single-blind clinical trial. The intervention group (n = 45) received 200 mg/day oral iron for 3 months and the control group (n = 45) received an oral placebo for the same period. Fasting blood sugar, complete blood count, and HbA1c were measured for all subjects at the beginning and the end of …
Transcription Factor 7-Like 2 (Tcf7l2) Gene Polymorphisms Are Strong Predictorsof Type 2 Diabetes Among Nonobese Diabetics In The Turkish Population, Dudu Erkoç Kaya, Hi̇lal Arikoğlu, Seyi̇t Ali̇ Kayiş, Onur Öztürk, Mustafa Sai̇t Gönen
Transcription Factor 7-Like 2 (Tcf7l2) Gene Polymorphisms Are Strong Predictorsof Type 2 Diabetes Among Nonobese Diabetics In The Turkish Population, Dudu Erkoç Kaya, Hi̇lal Arikoğlu, Seyi̇t Ali̇ Kayiş, Onur Öztürk, Mustafa Sai̇t Gönen
Turkish Journal of Medical Sciences
Background/aim: Type 2 diabetes (T2D) is a multifactorial disease, determined by environmental and genetic factors. Currently, the transcription factor 7-like 2 (TCF7L2) gene shows the strongest association with T2D. In this study, we investigated whether TCF7L2 gene polymorphisms are associated with T2D in a Turkish population. Materials and methods: Using PCR-RFLP and PCR-SSCP, we genotyped six intronic polymorphisms in the TCF7L2 gene, commonly associated with T2D, in 169 individuals with diabetes and 119 healthy controls. Results: We found that rs7903146 C -> T substitution in intron 3 (OR: 1.9, P = 0.005) and rs12255372 G -> T substitution in intron …
The Relationship Of Mean Platelet Volume With Retinopathy In Type 2 Diabetes Mellitus, Asli Araz Güngör, Gül Gürsoy, Fati̇h Güngör, Seyi̇t Murat Bayram, Eray Atalay
The Relationship Of Mean Platelet Volume With Retinopathy In Type 2 Diabetes Mellitus, Asli Araz Güngör, Gül Gürsoy, Fati̇h Güngör, Seyi̇t Murat Bayram, Eray Atalay
Turkish Journal of Medical Sciences
Background/aim: Patients with diabetes mellitus have an increased risk of developing micro- and macrovascular complications. Retinopathy is one of the most important complications of diabetes whose pathophysiological cause has not yet been determined. One candidate may be platelet volume. In this study we aimed to investigate the association between mean platelet volume and diabetic retinopathy. Materials and methods: Mean platelet volume levels were investigated in type 2 diabetic patients with and without retinopathy, and in healthy participants. After reclassifying our diabetics in terms of the presence or absence of hypertension and hyperlipidemia, we compared their mean platelet volumes. We then …
The Relationship Of Mean Platelet Volume With Microalbuminuriain Type 2 Diabetic Patients, Seyi̇t Murat Bayram, Gül Gürsoy, Asli Araz Güngör, Fati̇h Güngör, Eray Atalay
The Relationship Of Mean Platelet Volume With Microalbuminuriain Type 2 Diabetic Patients, Seyi̇t Murat Bayram, Gül Gürsoy, Asli Araz Güngör, Fati̇h Güngör, Eray Atalay
Turkish Journal of Medical Sciences
Background/aim: Activation and size of platelets have been suggested to be involved in the pathogenesis of vascular complications in diabetes mellitus. The purpose of the present study was to investigate the association of mean platelet volume with microalbuminuria in type 2 diabetic patients. Materials and methods: Mean platelet volume levels were investigated in healthy participants and type 2 diabetic patients with and without microalbuminuria. After their mean platelet volume values were compared, correlation of mean platelet volume with sex, duration of diabetes, microalbuminuria, fasting blood glucose, hemoglobin A1c, creatinine clearance, and body mass index was examined. Results: Mean platelet volume …
The Effects Of Short-Acting Analogue Insulins On Body Weight In Patients With Type 2 Diabetes Mellitus, Cumali̇ Karatoprak, Servet Yolbaş, Muharrem Kiskaç, Mehmet Zorlu, Adnan Yay, Mustafa Çakirca, Mehmetali̇ Çikrikçioğlu, Reha Erkoç, Ertuğrul Taşan
The Effects Of Short-Acting Analogue Insulins On Body Weight In Patients With Type 2 Diabetes Mellitus, Cumali̇ Karatoprak, Servet Yolbaş, Muharrem Kiskaç, Mehmet Zorlu, Adnan Yay, Mustafa Çakirca, Mehmetali̇ Çikrikçioğlu, Reha Erkoç, Ertuğrul Taşan
Turkish Journal of Medical Sciences
To investigate the effects of short-acting analogue insulins on weight, and to demonstrate the difference between analogues. Materials and methods: Our study included patients who have used only intensive insulin therapy with metformin. Those who took other oral antidiabetics, other insulin derivatives, or different insulin combinations were excluded from the study because of the adverse effects on patients' weights. Results: Our study included 118 patients who used insulin glargine with short-acting analogue insulins, i.e. insulin aspart (38 patients), insulin lispro (28 patients), and insulin glulisine (52 patients). After 3 to 6 months of treatment, significant weight gain was observed in …
Serum Lipoprotein(A) And High Sensitivity C Reactive Protein Levels In Saudi Patients With Type 2 Diabetes Mellitus And Their Relationship With Glycemic Control, Syed Shahid Habib
Serum Lipoprotein(A) And High Sensitivity C Reactive Protein Levels In Saudi Patients With Type 2 Diabetes Mellitus And Their Relationship With Glycemic Control, Syed Shahid Habib
Turkish Journal of Medical Sciences
To study serum lipoprotein(a) [Lp(a)] and high sensitivity C reactive protein (hsCRP) levels in Saudi patients with type 2 diabetes mellitus (DM) and their relationship with glycemic control. Materials and methods: A total of 201 subjects were selected for the study. The final selection included 103 patients with type 2 DM (64 males and 39 females) and 98 healthy control subjects (58 males and 40 females). Fasting venous blood samples were analyzed for glucose, glycosylated hemoglobin (HbA1c), lipids, Lp(a), and hsCRP levels. Results: Subjects with poor glycemic control showed significantly higher levels of fasting blood glucose levels (10.29 ± 3.56 …
Effect Of Telmisartan On Vascular Endothelium In Hypertensive And Type 2 Diabetic Hypertensive Patients, Burcu Barutçuoğlu, Zuhal Parildar, M. Işil Mutaf, Di̇lek Özmen, Emi̇n Ali̇oğlu, Sara Habi̇f, Oya Bayindir
Effect Of Telmisartan On Vascular Endothelium In Hypertensive And Type 2 Diabetic Hypertensive Patients, Burcu Barutçuoğlu, Zuhal Parildar, M. Işil Mutaf, Di̇lek Özmen, Emi̇n Ali̇oğlu, Sara Habi̇f, Oya Bayindir
Turkish Journal of Medical Sciences
Hypertension and type 2 diabetes mellitus (DM) cause endothelial dysfunction and may result in cardiovascular disease. The aim of this study was to assess endothelial dysfunction in essential hypertensives, and normotensive and hypertensive type 2 diabetics and to evaluate the effect of telmisartan on endothelium in hypertensives. Materials and methods: Eighteen essential hypertensives (group 1), 16 type 2 diabetic hypertensives (group 2), 10 type 2 diabetic normotensives (group 3), and 10 control subjects (group 4) were included in this study. Groups 1 and 2 received 40 mg/day telmisartan for 12 weeks and were evaluated at the beginning and end. Groups …